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significantly impair » significantly impairs (Expand Search), significantly impaired (Expand Search), significantly impact (Expand Search)
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921
Table_1_Outcomes of retroperitoneal fibrosis-related hydronephrosis and its risk factors for poor prognosis: a multi-center retrospective cohort study in Chinese patients.DOCX
Published 2024“…After 60.43 ± 34.53 months of follow-up, 36 patients had poor prognosis, which was associated with severe kidney impairment, bilateral hydronephrosis and inflammation status (elevated ESR and IgG) at diagnosis by case–control study. eGFR and creatinine were independent risk factors after adjusting for all other significant associations (p = 0.002 and p = 0.067, respectively). …”
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922
Data Sheet 1_The effects of sleep deprivation on cognitive flexibility: a scoping review of outcomes and biological mechanisms.docx
Published 2025“…The primary biological mechanisms involve decreased cerebral oxygen supply, impaired cerebrovascular reactivity, and alterations in gene expression and hormone levels. …”
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923
Image 1_Boys born with hypospadias and fetal growth restriction exhibit shorter anogenital distances: a retrospective cross-sectional study.tif
Published 2025“…Patients with hypospadias exhibited significantly shorter AGDs compared to the control group (P < 0.05). …”
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924
Image 3_Efficacy and safety of tocilizumab in managing cytokine release syndrome after CD19 CAR-T therapy for relapsed or refractory B-cell acute lymphoblastic leukemia.tiff
Published 2025“…Additionally, 10 patients showed decreased cytokine levels.Importantly, tocilizumab did not impair CAR-T cell expansion or efficacy, nor did it increase the incidence of adverse events.…”
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925
Table 1_Efficacy and safety of tocilizumab in managing cytokine release syndrome after CD19 CAR-T therapy for relapsed or refractory B-cell acute lymphoblastic leukemia.docx
Published 2025“…Additionally, 10 patients showed decreased cytokine levels.Importantly, tocilizumab did not impair CAR-T cell expansion or efficacy, nor did it increase the incidence of adverse events.…”
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926
Image 2_Efficacy and safety of tocilizumab in managing cytokine release syndrome after CD19 CAR-T therapy for relapsed or refractory B-cell acute lymphoblastic leukemia.tiff
Published 2025“…Additionally, 10 patients showed decreased cytokine levels.Importantly, tocilizumab did not impair CAR-T cell expansion or efficacy, nor did it increase the incidence of adverse events.…”
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927
Table 2_Efficacy and safety of tocilizumab in managing cytokine release syndrome after CD19 CAR-T therapy for relapsed or refractory B-cell acute lymphoblastic leukemia.doc
Published 2025“…Additionally, 10 patients showed decreased cytokine levels.Importantly, tocilizumab did not impair CAR-T cell expansion or efficacy, nor did it increase the incidence of adverse events.…”
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928
Image 1_Efficacy and safety of tocilizumab in managing cytokine release syndrome after CD19 CAR-T therapy for relapsed or refractory B-cell acute lymphoblastic leukemia.tiff
Published 2025“…Additionally, 10 patients showed decreased cytokine levels.Importantly, tocilizumab did not impair CAR-T cell expansion or efficacy, nor did it increase the incidence of adverse events.…”
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929
The effect of G83R mutation on transthyretin protein structural stability
Published 2024“…<p dir="ltr"><a href="" target="_blank">Transthyretin (TTR</a>) G83R mutation can cause vitreous amyloidosis and severely impair vision. Further understanding of the effect of G83R mutation on TTR structure and stability will help to understand its pathogenesis. …”
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930
Data Sheet 1_Integrated physiological, transcriptomic, and metabolomic analyses of Chrysanthemum ‘Boju’ under excessive indole-3-acetic acid stress.pdf
Published 2025“…Exogenous IAA treatment also led to a significant reduction in endogenous hormone levels, including gibberellins (GA<sub>3</sub> and GA<sub>4</sub>), abscisic acid (ABA), and IAA, with decreases of 93%, 45%, 99%, and 99%, respectively.Transcriptomic and metabolomic analyses identified 263 differentially expressed metabolites and 144 differentially expressed genes.…”
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931
Supplementary file 1_Haptic feedback as affective amplifier: enhanced fear perception affects cognitive performance and avoidance actions in VR height exposure.docx
Published 2025“…We have multimodal assessed of physiological (EEG, peripheral physiological arousal), behavioral (movement distance, eye movement), and cognitive performance (nine-light task accuracy rates and reaction time) during fear induction. Results revealed significant declines in task accuracy and prolonged reaction times during the shaking condition, indicating resource competition where threat processing impaired goal-directed motor execution. …”
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932
Effects of efgartigimod treatment on humoral and cellular immune responses: analysis of T-cell-dependent antibody response in cynomolgus monkeys
Published 2025“…KLH challenges occurred during both the dosing phase and the recovery phase. No statistically significant differences emerged in anti-KLH IgM levels between the efgartigimod and control groups. …”
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933
Data Sheet 1_Finite-element analysis-based design and efficacy assessment of a three-dimensional anisotropic heel cushioning pad for diabetic foot management.xlsx
Published 2025“…Background<p>Diabetic foot ulcer (DFU) is a common complication observed in diabetic patients, which can lead to lower limb amputation in severe cases and seriously impair the patient’s mobility and even endanger life. …”
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934
Image 1_Finite-element analysis-based design and efficacy assessment of a three-dimensional anisotropic heel cushioning pad for diabetic foot management.jpeg
Published 2025“…Background<p>Diabetic foot ulcer (DFU) is a common complication observed in diabetic patients, which can lead to lower limb amputation in severe cases and seriously impair the patient’s mobility and even endanger life. …”
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935
Table 1_Finite-element analysis-based design and efficacy assessment of a three-dimensional anisotropic heel cushioning pad for diabetic foot management.docx
Published 2025“…Background<p>Diabetic foot ulcer (DFU) is a common complication observed in diabetic patients, which can lead to lower limb amputation in severe cases and seriously impair the patient’s mobility and even endanger life. …”
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936
Data Sheet 3_The power of GM-CSF: immune regulation in the defense against Phialophora verrucosa infection.pdf
Published 2025“…</p>Results<p>Compared to WT mice, GM-CSF deficiency significantly delayed fungal clearance and prolonged disease progression, accompanied by reduced inflammatory responses and decreased neutrophil infiltration. …”
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937
Data Sheet 1_The power of GM-CSF: immune regulation in the defense against Phialophora verrucosa infection.pdf
Published 2025“…</p>Results<p>Compared to WT mice, GM-CSF deficiency significantly delayed fungal clearance and prolonged disease progression, accompanied by reduced inflammatory responses and decreased neutrophil infiltration. …”
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938
<b><i>Escherichia coli α-hemolysin induces red blood cell retention in a microfluidic spleen-like device</i></b>
Published 2025“…</p><p dir="ltr">In the first device, which mimics the mechanical deformation of RBCs in narrow capillaries, HlyA sublytic concentrations were found to significantly impair RBC deformability. These changes were accompanied by an increase in cytosolic Ca<sup>2+</sup> and volume expansion. …”
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939
Data Sheet 4_The power of GM-CSF: immune regulation in the defense against Phialophora verrucosa infection.pdf
Published 2025“…</p>Results<p>Compared to WT mice, GM-CSF deficiency significantly delayed fungal clearance and prolonged disease progression, accompanied by reduced inflammatory responses and decreased neutrophil infiltration. …”
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940
Data Sheet 5_The power of GM-CSF: immune regulation in the defense against Phialophora verrucosa infection.pdf
Published 2025“…</p>Results<p>Compared to WT mice, GM-CSF deficiency significantly delayed fungal clearance and prolonged disease progression, accompanied by reduced inflammatory responses and decreased neutrophil infiltration. …”