Table 1_Association of cardiorespiratory fitness with phenotypic age in younger population: a study based on the NHANES database.docx by Yi Shen (152956)

“…Interestingly, in the population of over 29 years’ old, a significant interaction between obesity and impaired CRF for PAA was observed (p = 0.018; p = 0.026).…”

Data Sheet 2_Association of cardiorespiratory fitness with phenotypic age in younger population: a study based on the NHANES database.pdf by Yi Shen (152956)

“…Interestingly, in the population of over 29 years’ old, a significant interaction between obesity and impaired CRF for PAA was observed (p = 0.018; p = 0.026).…”

Data Sheet 1_Soil microbiome dysbiosis and rhizosphere metabolic dysfunction drive continuous cropping obstacles of Codonopsis tangshen.docx by Dabing Xu (18961138)

“…However, their abundance decreased significantly under continuous cropping, ultimately disrupting soil carbon cycling. …”

Data Sheet 1_Leaf hydraulic decline coordinates stomatal and photosynthetic limitations through anatomical adjustments under drought stress in cotton.docx by Xiuli Li (133764)

“…By day 28 after drought stress, drought stress significantly impaired leaf hydraulics, as demonstrated by decreases in leaf hydraulic conductivity (K_leaf) (9.81% under MD, 12.93% under SD) and leaf water potential (5.79% under MD, 17.54% under SD). …”

Data Sheet 1_Confronting the anxiety of Generation Z: electroacupuncture therapy regulates oxidative stress and microglia activity in amygdala-basolateral of socially isolated mice... by Tong Yin (3576917)

“…Introduction<p>Anxiety disorders are prevalent mental health conditions characterized by significant impairments in daily functioning and social interactions. …”

Supplementary Materials -Table by Shaojie Zhang (20807333)

“…In the present study, we discovered that hypobaric hypoxia exposure not only reduced the number of colonic goblet cells in mice by 27.6% but also impaired their mucus secretion. Transcriptome sequencing analysis of sorted goblet cells from the mice colon revealed significant changes in gene expression profiles, particularly in the expression of canonical goblet cell markers such as calcium-activated chloride channel regulator 1 (Clca1) and Fcγ-binding protein (Fcgbp). …”

Supplementary Material for: Acute interstitial nephritis associated to Pertussis infection: a case report and review of the literature by figshare admin karger (2628495)

“…Despite improvement in respiratory symptoms, renal function remained impaired. Renal biopsy revealed moderate tubulointerstitial nephritis, and the patient was treated with prednisone, leading to gradual recovery of renal function, with serum creatinine decreasing to 2.3 mg/dL at discharge and 1.85 mg/dL three weeks later. …”

Supplementary Materials - Figure by Shaojie Zhang (20807333)

“…In the present study, we discovered that hypobaric hypoxia exposure not only reduced the number of colonic goblet cells in mice by 27.6% but also impaired their mucus secretion. Transcriptome sequencing analysis of sorted goblet cells from the mice colon revealed significant changes in gene expression profiles, particularly in the expression of canonical goblet cell markers such as calcium-activated chloride channel regulator 1 (Clca1) and Fcγ-binding protein (Fcgbp). …”

Data Sheet 1_Ibrutinib enhances the bias of T cell responses towards staphylococcal superantigens sustaining inflammation in chronic lymphocytic leukaemia.pdf by Fisal Tantoush (20936264)

“…Recently, carriage of the endemic Staphylococcus aureus (SA) was associated with lymphocytosis and decreased survival in CLL patients. We then hypothesized that exposure to staphylococcal superantigens (SAgs), known to promote hyper-inflammatory responses, impairs immunity and increases severe infection risk in CLL patients. …”

Investigation of changes in the choice reaction time with levodopa in patients with Parkinson’s disease by Halil Onder (10368032)

“…The comparative analyses between medication-off and -on states revealed that the MDS-UPDRS-3 scores decreased significantly during the medication-on states (<i>p</i> < 0.001, d = 1.09). …”

Deciphering the involvement of norepinephrine and β-adrenergic receptor subtypes in glucose induced insulin secretion: an integrated <i>in silico</i> and <i>in vitro</i> exploratio... by Vijayalakshmi Gangadhara (20481150)

“…The nonselective β-AR antagonist propranolol significantly decreased (<i>p</i> < 0.01)insulin secretion, suggesting alternative interactions with β1-AR and β2-AR despite lacking hydrogen bonds. …”

Data Sheet 1_Psychological Well-Being in Adults Across the COVID-19 Pandemic: A Two-Year Longitudinal Study.docx by Melanie Ehrler (9759152)

“…Decreasing or consistently low well-being was significantly associated with younger age, limited social support, caregiving responsibilities, concerns about COVID-19 infection, and stress due to pandemic-related changes.…”

Image4_Causal association between matrix metalloproteinases and diabetic neuropathy: a two-sample Mendelian randomization study.tif by Chao Bai (4428472)

“…Objective<p>Diabetic neuropathy (DN), a common and debilitating complication of diabetes, significantly impairs the quality of life of affected individuals. …”

Table 1_Integrated analysis of serum metabolomics and fecal microbiome in infants with necrotizing enterocolitis.docx by Zhi-ying Lin (12997350)

“…Correspondingly, KEGG functional gene analysis demonstrated impaired metabolism in NEC-D. Serum metabolomics identified significantly decreased ornithine, DL-arginine, L-threonine, leucine, and D-proline in NEC-D versus non-NEC. …”

Image2_Causal association between matrix metalloproteinases and diabetic neuropathy: a two-sample Mendelian randomization study.tif by Chao Bai (4428472)

“…Objective<p>Diabetic neuropathy (DN), a common and debilitating complication of diabetes, significantly impairs the quality of life of affected individuals. …”

Video 2_Muscle-specific Bet1L knockdown induces neuromuscular denervation, motor neuron degeneration, and motor dysfunction in a rat model of familial ALS.mp4 by Adam Eckardt (20573576)

“…After 3 weeks, intramuscular Bet1L siRNA injection significantly increased the number of denervated NMJs in the injected muscle. …”

Image1_Causal association between matrix metalloproteinases and diabetic neuropathy: a two-sample Mendelian randomization study.tif by Chao Bai (4428472)

“…Objective<p>Diabetic neuropathy (DN), a common and debilitating complication of diabetes, significantly impairs the quality of life of affected individuals. …”

Data Sheet 1_Radiomics reveals the biological basis for non-small cell lung cancer prognostic stratification by reflecting tumor immune microenvironment heterogeneity.docx by Qing Huang (240196)

“…Immune microenvironment profiling showed significantly reduced immune scores and decreased proportions of naive B cells in high-risk patients, indicating impaired immune activity. …”

Video 1_Muscle-specific Bet1L knockdown induces neuromuscular denervation, motor neuron degeneration, and motor dysfunction in a rat model of familial ALS.mp4 by Adam Eckardt (20573576)

“…After 3 weeks, intramuscular Bet1L siRNA injection significantly increased the number of denervated NMJs in the injected muscle. …”

Data Sheet 1_RPL41 inhibits the proliferation and migration of retinoblastoma through the ARL5B-associated lysosomal trafficking.pdf by Ye Li (290115)

“…ARL5B expression was significantly downregulated in treated Y79 and Weri-RB1 cells. …”