بدائل البحث:
significant decrease » significant increase (توسيع البحث), significantly increased (توسيع البحث)
significantly impair » significantly impairs (توسيع البحث), significantly impaired (توسيع البحث), significantly impact (توسيع البحث)
significant decrease » significant increase (توسيع البحث), significantly increased (توسيع البحث)
significantly impair » significantly impairs (توسيع البحث), significantly impaired (توسيع البحث), significantly impact (توسيع البحث)
-
1341
Data Sheet 1_Top motor and non-motor complaints in patients with Parkinson's disease.docx
منشور في 2025"…Cognitive impairment was a significant predictor of non-motor symptoms in their top three tiers [odds ratio [OR]: 3.88 (95% CI: 1.647 to 9.169)]. …"
-
1342
Image3_Dexamethasone and IFN-γ primed mesenchymal stem cells conditioned media immunomodulates aberrant NETosis in SLE via PGE2 and IDO.tif
منشور في 2024"…Background<p>Systemic Lupus Erythematosus (SLE) is characterized by dysregulated immune responses, with neutrophil extracellular traps (NETs) playing a significant role. NETs are recognized by autoantibodies in SLE patients, exacerbating pathology. …"
-
1343
Image2_Dexamethasone and IFN-γ primed mesenchymal stem cells conditioned media immunomodulates aberrant NETosis in SLE via PGE2 and IDO.tif
منشور في 2024"…Background<p>Systemic Lupus Erythematosus (SLE) is characterized by dysregulated immune responses, with neutrophil extracellular traps (NETs) playing a significant role. NETs are recognized by autoantibodies in SLE patients, exacerbating pathology. …"
-
1344
Image 1_Dysfunctional β-cell autophagy induces β-cell stress and enhances islet immunogenicity.tiff
منشور في 2025"…Previously, we discovered that β-cell autophagy is impaired prior to the onset of T1D, implicating this pathway in T1D pathogenesis.…"
-
1345
Image 3_Dysfunctional β-cell autophagy induces β-cell stress and enhances islet immunogenicity.tiff
منشور في 2025"…Previously, we discovered that β-cell autophagy is impaired prior to the onset of T1D, implicating this pathway in T1D pathogenesis.…"
-
1346
Image 4_Dysfunctional β-cell autophagy induces β-cell stress and enhances islet immunogenicity.tif
منشور في 2025"…Previously, we discovered that β-cell autophagy is impaired prior to the onset of T1D, implicating this pathway in T1D pathogenesis.…"
-
1347
Image 2_Dysfunctional β-cell autophagy induces β-cell stress and enhances islet immunogenicity.tiff
منشور في 2025"…Previously, we discovered that β-cell autophagy is impaired prior to the onset of T1D, implicating this pathway in T1D pathogenesis.…"
-
1348
Data Sheet 1_Improved myocardial mitochondrial energy metabolism in rats with chronic heart failure by modifying fatty acid oxidation using an extract of sand-fired aconite (Jianch...
منشور في 2025"…</p>Results<p>SFAS significantly improved cardiac function in CHF rats. …"
-
1349
Table 1_Dietary quercetagetin attenuates H2O2-induced oxidative damage and preserves meat quality in broilers by modulating redox status and Nrf2/ferroptosis signaling pathway.docx
منشور في 2025"…Meanwhile, the addition of QG to the diet increased the mRNA expressions of Nrf2 and TFR1, showing no significant difference from those of the control group. …"
-
1350
KIF5A-dependent axonal transport deficiency disrupts autophagic flux in trimethyltin chloride-induced neurotoxicity
منشور في 2024"…Further analysis indicated significant impairment of autophagic flux by TMT via suppressed lysosomal function, such as by inhibiting lysosomal proteolysis and changing the lysosomal pH, thereby contributing to defects in autophagic clearance and subsequently leading to nerve cell death. …"
-
1351
Supporting data for “Androgen receptor modulates chemotherapy response in breast cancer”
منشور في 2025"…For palbociclib, a CDK4/6 inhibitor, AR activation induced RB1 polyubiquitination and degradation, diminishing RB1 levels—a key downstream target of CDK4/6—and thus impairing palbociclib efficacy. Chromatin immunoprecipitation (ChIP) sequencing identified 1,209 AR-regulated genes, with gene ontology (GO) analysis highlighting significant enrichment of ubiquitin-related genes. qPCR validation pinpointed TRIM37, an AR-regulated E3 ligase, as a mediator of RB1 degradation. …"
-
1352
Table 1_Impact of recent COVID-19 infection on liver and kidney transplantation – a worldwide meta-analysis and systematic review.docx
منشور في 2025"…</p>Results<p>Transplantation of COVID-19 positive donors did not result in an impaired graft survival for liver or kidney transplantation up to 180-days of follow up. …"
-
1353
Supplementary Material for: Exclusively macular phenotype of non-syndromic MFSD8-related disease: A Case Report
منشور في 2025"…These included decreased central vision, visual distortions, photophobia, poor depth perception, glare, impaired dark/light adaptation, difficulty reading, depressed multifocal ERG responses and central ellipsoid dropout on SD-OCT. …"
-
1354
Data Sheet 1_Metabolic adaptation to acute metabolic stress via PFKFB3 upregulation in rodent beta cells.doc
منشور في 2025"…Knockdown of PFKFB3 or pharmacological inhibition of glycolysis resulted in decreased insulin secretion and impaired glucose tolerance. …"