Supplementary Material for: Impairment of Renal Function in Hermansky-Pudlak Syndrome by Yokoyama T. (4606381)

“…Calculated eGFR of adult patients with different HPS types differed significantly, and calculated eGFR of pediatric and adult patients with BLOC-3 disorders was significantly lower than that of patients with BLOC-2 disorders. …”

Flowchart of the study population. by Gábor Szaló (22615130)

“…Among those 803 individuals who did not take antihypertensive medication, there was a significant association in linear regression between increase in PSS-10 and decrease in C2 (B: −0.2, 95% CI: −0.4- −0.02; p = 0.03) that was lost after adjustment for physical activity (B: −0.16, 95% CI: −0.35–0.03; p = 0.1). …”

Characteristics of study population. by Gábor Szaló (22615130)

“…Among those 803 individuals who did not take antihypertensive medication, there was a significant association in linear regression between increase in PSS-10 and decrease in C2 (B: −0.2, 95% CI: −0.4- −0.02; p = 0.03) that was lost after adjustment for physical activity (B: −0.16, 95% CI: −0.35–0.03; p = 0.1). …”

Image 2_PLK1 inhibition impairs erythroid differentiation.jpeg by Peijun Jia (11334594)

“…More specifically, PLK1 inhibition impaired the differentiation and erythroid commitment of hematopoietic stem cells in the bone marrow, resulting in abnormal accumulation of BFU-E cells and reduced proliferation and differentiation of CFU-E, and a decrease in the number of terminal erythrocytes. …”

Image 1_PLK1 inhibition impairs erythroid differentiation.jpeg by Peijun Jia (11334594)

“…More specifically, PLK1 inhibition impaired the differentiation and erythroid commitment of hematopoietic stem cells in the bone marrow, resulting in abnormal accumulation of BFU-E cells and reduced proliferation and differentiation of CFU-E, and a decrease in the number of terminal erythrocytes. …”

MiRNA primer sequences. by Hang Wu (5072618)

“…Knockdown of miR-145a-3p in MC3T3-E1 cells after dexamethasone action significantly improved the expression of their impaired osteogenic indicators. …”

Osteogenesis-related primer sequences. by Hang Wu (5072618)

“…Knockdown of miR-145a-3p in MC3T3-E1 cells after dexamethasone action significantly improved the expression of their impaired osteogenic indicators. …”

Strains used in this study. by Zhongjiao Liu (11877464)

“…Under glucose signal, PoFbx23 absence (Δ<i>fbx23</i>) results in decreased transcription levels of the <i>brlA</i> gene which encodes the master regulator for asexual development and six spore pigmentation genes (<i>abrB</i>→<i>abrA</i>→<i>aygB</i>→<i>arpA</i>→<i>arpB</i>→<i>albA</i>) which encode the proteins in the dihydroxynaphthalene-melanin pathway, along with impaired conidiation. …”

Data that underlies the ChIP-qPCR in this paper. by Zhongjiao Liu (11877464)

“…Under glucose signal, PoFbx23 absence (Δ<i>fbx23</i>) results in decreased transcription levels of the <i>brlA</i> gene which encodes the master regulator for asexual development and six spore pigmentation genes (<i>abrB</i>→<i>abrA</i>→<i>aygB</i>→<i>arpA</i>→<i>arpB</i>→<i>albA</i>) which encode the proteins in the dihydroxynaphthalene-melanin pathway, along with impaired conidiation. …”

Data that underlies the RT-qPCR in this paper. by Zhongjiao Liu (11877464)

“…Under glucose signal, PoFbx23 absence (Δ<i>fbx23</i>) results in decreased transcription levels of the <i>brlA</i> gene which encodes the master regulator for asexual development and six spore pigmentation genes (<i>abrB</i>→<i>abrA</i>→<i>aygB</i>→<i>arpA</i>→<i>arpB</i>→<i>albA</i>) which encode the proteins in the dihydroxynaphthalene-melanin pathway, along with impaired conidiation. …”

Interoceptive Awareness Is Associated With Impaired Awareness of Hypoglycemia in Adults With Type 1 Diabetes by Austin M. Matus (19933218)

“…</p><p dir="ltr">Results</p><p dir="ltr">Significant relationships were observed between IAH and two MAIA-2 scales. …”

Inhibition of AurA or HDAC6 by inhibitors preserves ciliary structure during porcine CoVs infection. by Tenghan Zhuang (22238809)

Unraveling the Mechanism of 1‑Deoxynojirimycin (DNJ) Accumulation: The Role of SWEET3 in Mulberry Chloroplasts by Zhen Yang (107412)

“…Molecular docking revealed that acidic residues E68 and D126 are key DNJ-binding sites and their mutation impaired transport activity. Transient overexpression or RNA interference of <i>SWEET3</i> in mulberry leaves significantly increased or decreased DNJ levels, respectively, while stable overexpression in hairy roots enhanced DNJ accumulation. …”

Effect of inhibitors on the growth of <i>P. falciparum</i> and <i>P. berghei</i> blood stage parasites. by Aastha Varshney (22601181)

Alp5a and Alp5b are not individually required for asexual blood stage propagation, but simultaneously, they are indispensable for parasite viability. by Aastha Varshney (22601181)

Scatterplots of respiratory rate and age by sex. by Ina-Maria Rückert-Eheberg (2824901)

“…In an adjusted logistic regression model, age, abdominal obesity, diabetes, COPD, smoking, and low education were significantly associated with elevated respiratory rate. …”

Flow chart of the study population. by Ina-Maria Rückert-Eheberg (2824901)

“…In an adjusted logistic regression model, age, abdominal obesity, diabetes, COPD, smoking, and low education were significantly associated with elevated respiratory rate. …”

Image 2_Impaired K48-polyubiquitination downmodulates mouse norovirus propagation.tiff by Emmrich Wakeford (21249104)

“…Consequently, the number of viral genome copies or viral titers were also significantly decreased in the YFP-Ubiquitin_K48R cells compared to the YFP-Ubiquitin_WT cells. …”

Image 1_Impaired K48-polyubiquitination downmodulates mouse norovirus propagation.tiff by Emmrich Wakeford (21249104)

“…Consequently, the number of viral genome copies or viral titers were also significantly decreased in the YFP-Ubiquitin_K48R cells compared to the YFP-Ubiquitin_WT cells. …”

Investigating the effects of ankle foot orthoses on electromyography in impaired populations: a systematic review by Sally Kenworthy (20873172)

“…</p> <p></p><p>Ankle foot Orthosis (AFO) intervention demonstrates diverse effects on the timing and amplitude of electromyography (EMG) measures, with significant variability in direction, magnitude, and interpretation across studies, necessitating personalized approaches.…”