Data Sheet 1_Tcirg1 deficiency delays osteoarthritis progression by impairing lysosome acidification and peripheral accumulation in osteoclasts.docx by Rui Sun (177521)

“…Tcirg1 deficiency in knockout mice delayed OA progression, as evidenced by reduced cartilage damage, improved subchondral bone mass, and decreased osteoclast activity. In vitro, Tcirg1 expression increased during osteoclast differentiation, and its knockdown inhibited osteoclast fusion and bone resorption by impairing lysosome acidification and peripheral accumulation.…”

DataSheet4_Deficiency of autism susceptibility gene Trio in cerebellar Purkinje cells leads to delayed motor impairments.zip by Jinxin Wang (1696837)

“…Although Trio^{fl/fl; Pcp2-Cre} mice showed significant impairments of spontaneous locomotion activity in both 12-week and 20-week ages, only the 20-week but not 12-week Trio^{fl/fl; Pcp2-Cre} mice showed extra mild abnormal motor, fine motor coordination, and gait. …”

DataSheet5_Deficiency of autism susceptibility gene Trio in cerebellar Purkinje cells leads to delayed motor impairments.zip by Jinxin Wang (1696837)

“…Although Trio^{fl/fl; Pcp2-Cre} mice showed significant impairments of spontaneous locomotion activity in both 12-week and 20-week ages, only the 20-week but not 12-week Trio^{fl/fl; Pcp2-Cre} mice showed extra mild abnormal motor, fine motor coordination, and gait. …”

DataSheet1_Deficiency of autism susceptibility gene Trio in cerebellar Purkinje cells leads to delayed motor impairments.zip by Jinxin Wang (1696837)

“…Although Trio^{fl/fl; Pcp2-Cre} mice showed significant impairments of spontaneous locomotion activity in both 12-week and 20-week ages, only the 20-week but not 12-week Trio^{fl/fl; Pcp2-Cre} mice showed extra mild abnormal motor, fine motor coordination, and gait. …”

DataSheet3_Deficiency of autism susceptibility gene Trio in cerebellar Purkinje cells leads to delayed motor impairments.zip by Jinxin Wang (1696837)

“…Although Trio^{fl/fl; Pcp2-Cre} mice showed significant impairments of spontaneous locomotion activity in both 12-week and 20-week ages, only the 20-week but not 12-week Trio^{fl/fl; Pcp2-Cre} mice showed extra mild abnormal motor, fine motor coordination, and gait. …”

DataSheet2_Deficiency of autism susceptibility gene Trio in cerebellar Purkinje cells leads to delayed motor impairments.zip by Jinxin Wang (1696837)

“…Although Trio^{fl/fl; Pcp2-Cre} mice showed significant impairments of spontaneous locomotion activity in both 12-week and 20-week ages, only the 20-week but not 12-week Trio^{fl/fl; Pcp2-Cre} mice showed extra mild abnormal motor, fine motor coordination, and gait. …”

Data Sheet 1_Electroacupuncture treatment can improve cognitive impairment in spontaneously hypertensive rats: a preliminary DTI study.docx by Ji-peng Liu (14764009)

“…Background<p>Hypertension is a significant risk factor for cognitive impairment. Our group’s previous rs-fMRI study has found that acupuncture can enhance the functional connectivity of brain regions related to cognitive function, thereby protecting the cognitive function of spontaneously hypertensive rats (SHRs).…”

Data Sheet 1_The potential of olfaction loss to induce cognitive impairment and anxiety behavior in mice via the microbiota-gut-brain axis.pdf by Xiangyu Zhao (1497469)

“…</p>Results<p>Olfactory loss not only causes a significant decrease in food intake and body weight and an increase in O₂ consumption but also induces cognitive impairment and anxiety behavior. …”

Movie 1 TRAF7^fl*/fl* vs. WT. by Erdyni N. Tsitsikov (20384719)

“…Transcriptome analysis at P14 and P23 revealed significantly reduced expression of mitochondrial genes in <i>Rik</i>^<i>null</i> brains compared to wild type controls including <i>mt-Nd4</i>, <i>mt-Cytb</i>, <i>mt-Nd2</i>, <i>mt-Co1</i>, <i>mt-Atp6</i>, and others. …”

Images analyzed for Fig 7. by Erdyni N. Tsitsikov (20384719)

“…Transcriptome analysis at P14 and P23 revealed significantly reduced expression of mitochondrial genes in <i>Rik</i>^<i>null</i> brains compared to wild type controls including <i>mt-Nd4</i>, <i>mt-Cytb</i>, <i>mt-Nd2</i>, <i>mt-Co1</i>, <i>mt-Atp6</i>, and others. …”

Movie 2 Rik^null vs. WT. by Erdyni N. Tsitsikov (20384719)

“…Transcriptome analysis at P14 and P23 revealed significantly reduced expression of mitochondrial genes in <i>Rik</i>^<i>null</i> brains compared to wild type controls including <i>mt-Nd4</i>, <i>mt-Cytb</i>, <i>mt-Nd2</i>, <i>mt-Co1</i>, <i>mt-Atp6</i>, and others. …”

Raw data for figures. by Erdyni N. Tsitsikov (20384719)

“…Transcriptome analysis at P14 and P23 revealed significantly reduced expression of mitochondrial genes in <i>Rik</i>^<i>null</i> brains compared to wild type controls including <i>mt-Nd4</i>, <i>mt-Cytb</i>, <i>mt-Nd2</i>, <i>mt-Co1</i>, <i>mt-Atp6</i>, and others. …”

Uncropped DNA gel used for Fig 1B. by Erdyni N. Tsitsikov (20384719)

“…Transcriptome analysis at P14 and P23 revealed significantly reduced expression of mitochondrial genes in <i>Rik</i>^<i>null</i> brains compared to wild type controls including <i>mt-Nd4</i>, <i>mt-Cytb</i>, <i>mt-Nd2</i>, <i>mt-Co1</i>, <i>mt-Atp6</i>, and others. …”

Images analyzed for Table 1. by Erdyni N. Tsitsikov (20384719)

“…Transcriptome analysis at P14 and P23 revealed significantly reduced expression of mitochondrial genes in <i>Rik</i>^<i>null</i> brains compared to wild type controls including <i>mt-Nd4</i>, <i>mt-Cytb</i>, <i>mt-Nd2</i>, <i>mt-Co1</i>, <i>mt-Atp6</i>, and others. …”

Supplementary file 1_Resting-state EEG alterations and cognitive impairment in atrial fibrillation: insights into neural biomarkers and functional connectivity.docx by Min-qiang Bao (21570074)

“…</p>Results<p>AF patients had significantly lower MoCA scores. PSD analysis showed increased δ and θ and decreased α and β activity. …”

E9.5 <i>TRAF7</i>^<i>KO</i>-asterisk vs. WT DEGs. by Erdyni N. Tsitsikov (20384719)

“…Transcriptome analysis at P14 and P23 revealed significantly reduced expression of mitochondrial genes in <i>Rik</i>^<i>null</i> brains compared to wild type controls including <i>mt-Nd4</i>, <i>mt-Cytb</i>, <i>mt-Nd2</i>, <i>mt-Co1</i>, <i>mt-Atp6</i>, and others. …”

P23 <i>Rik</i>^<i>null</i> vs. WT DEGs. by Erdyni N. Tsitsikov (20384719)

“…Transcriptome analysis at P14 and P23 revealed significantly reduced expression of mitochondrial genes in <i>Rik</i>^<i>null</i> brains compared to wild type controls including <i>mt-Nd4</i>, <i>mt-Cytb</i>, <i>mt-Nd2</i>, <i>mt-Co1</i>, <i>mt-Atp6</i>, and others. …”

P14 <i>Rik</i>^<i>null</i> vs. WT DEGs. by Erdyni N. Tsitsikov (20384719)

“…Transcriptome analysis at P14 and P23 revealed significantly reduced expression of mitochondrial genes in <i>Rik</i>^<i>null</i> brains compared to wild type controls including <i>mt-Nd4</i>, <i>mt-Cytb</i>, <i>mt-Nd2</i>, <i>mt-Co1</i>, <i>mt-Atp6</i>, and others. …”

GnRH antagonist impairs the process of embryo implantation by inhibiting motility of endometrial stromal cells through reducing c-kit expression by Jun Tan (46388)

“…</i> 56.1%, <i>p</i> < .001) in the GnRH-ant group were significantly decreased. Contrarily, the rate of early miscarriage in the GnRH-ant group (13.95% <i>vs.…”

Table 1_Association between serum albumin and severe impairment of activities of daily living in patients with stroke: a cross-sectional study.docx by Ranran Bi (20505614)

“…The OR for significant impairment of ADLs was 0.680 (95% CI: 0.568–0.814, p < 0.001) in participants with serum albumin levels <38.0 g/L. …”