Data Sheet 1_Adult-onset hypothyroidism induces granulosa cell apoptosis and affects ovarian follicle development in rats.docx by Shuyue Li (14585343)

“…</p>Results<p>Our results showed that, in addition to a decrease in thyroid hormones, the body weight was significantly reduced, while the estrus cycle was prolonged in the hypothyroidism group. …”

Supplementary file 1_Potential antitumoral effects of SRPK1 inhibition through modulation of VEGF splicing in pituitary somatotroph tumoral cells.jpeg by Donatella Treppiedi (10146335)

“…Moreover, SRPIN340 significantly decreased both transcript (-56.3 (38.6)%, p<0.01 vs control cells) and protein levels (-33.5 (3.4)%, p<0.05 vs control cells) of the pro-survival VEGF164a isoform. …”

Image 1_Potential antitumoral effects of SRPK1 inhibition through modulation of VEGF splicing in pituitary somatotroph tumoral cells.jpg by Donatella Treppiedi (10146335)

“…Moreover, SRPIN340 significantly decreased both transcript (-56.3 (38.6)%, p<0.01 vs control cells) and protein levels (-33.5 (3.4)%, p<0.05 vs control cells) of the pro-survival VEGF164a isoform. …”

Table 1_Relationship between nocturia, depression, and cognitive function and the mediating effects of nutritional indexes in older adults: data from NHANES 2011–2014.docx by Yin Xu (159474)

“…Male/female-stratified analysis showed that animal fluency scores (AFS), DSS, and PHQ-9 scores were significantly correlated with the risk of nocturia in females (p < 0.05), and PHQ-9 scores were significantly associated with the risk of nocturia in males (p < 0.05). …”

Table 3_Exploring the effects of dietary methionine supplementation on European seabass mucosal immune responses against Tenacibaculum maritimum.xlsx by Inês Carvalho (59935)

“…These findings, together with the lower mRNA expression of proinflammatory genes in the head kidney and the higher mortality rates observed in this group, suggest a potential impairment of the immune response.`</p>Discussion<p>Overall, these findings indicate that dietary methionine supplementation may significantly influence both systemic and local immune responses in European seabass, highlighting the need for careful consideration when supplementing diets with methionine.…”

Table 2_Exploring the effects of dietary methionine supplementation on European seabass mucosal immune responses against Tenacibaculum maritimum.xlsx by Inês Carvalho (59935)

“…These findings, together with the lower mRNA expression of proinflammatory genes in the head kidney and the higher mortality rates observed in this group, suggest a potential impairment of the immune response.`</p>Discussion<p>Overall, these findings indicate that dietary methionine supplementation may significantly influence both systemic and local immune responses in European seabass, highlighting the need for careful consideration when supplementing diets with methionine.…”

Table 4_Exploring the effects of dietary methionine supplementation on European seabass mucosal immune responses against Tenacibaculum maritimum.xlsx by Inês Carvalho (59935)

“…These findings, together with the lower mRNA expression of proinflammatory genes in the head kidney and the higher mortality rates observed in this group, suggest a potential impairment of the immune response.`</p>Discussion<p>Overall, these findings indicate that dietary methionine supplementation may significantly influence both systemic and local immune responses in European seabass, highlighting the need for careful consideration when supplementing diets with methionine.…”

Table 5_Exploring the effects of dietary methionine supplementation on European seabass mucosal immune responses against Tenacibaculum maritimum.xlsx by Inês Carvalho (59935)

“…These findings, together with the lower mRNA expression of proinflammatory genes in the head kidney and the higher mortality rates observed in this group, suggest a potential impairment of the immune response.`</p>Discussion<p>Overall, these findings indicate that dietary methionine supplementation may significantly influence both systemic and local immune responses in European seabass, highlighting the need for careful consideration when supplementing diets with methionine.…”

Table 1_Exploring the effects of dietary methionine supplementation on European seabass mucosal immune responses against Tenacibaculum maritimum.docx by Inês Carvalho (59935)

“…These findings, together with the lower mRNA expression of proinflammatory genes in the head kidney and the higher mortality rates observed in this group, suggest a potential impairment of the immune response.`</p>Discussion<p>Overall, these findings indicate that dietary methionine supplementation may significantly influence both systemic and local immune responses in European seabass, highlighting the need for careful consideration when supplementing diets with methionine.…”

Effect of the strategy game Mangala on cognitive function, anxiety, depression, and fine motor skills in individuals with Alzheimer’s disease: A randomized controlled trial by Aziz Dengiz (20494793)

“…<p>Cognitive impairment, changes in mood, and decrease in fine motor skills are some of the most common symptoms experienced by individuals with Alzheimer’s Disease (AD). …”

Table 1_Inverse association between triglyceride–glucose index and maximal oxygen uptake in US young and middle-aged population: a cross-sectional study.docx by Bin Zhang (64682)

“…</p>Conclusions<p>In the US young and middle-aged population, the TyG index was significantly adversely associated with VO₂max levels. …”

Data Sheet 1_Mechanism of mTOR/RILP-regulated autophagic flux in increased susceptibility to myocardial ischemia-reperfusion in diabetic mice.zip by Jiyao Zhao (10505867)

“…WB showed that P62 was significantly increased and RILP was significantly decreased in diabetic mice subjected to I/RI compared to healthy mice. …”

Table 1_Multi-omics analyses reveal altered gut microbial thiamine production in obesity.xlsx by Yu Xia (8822)

“…</p>Results<p>Metabolomic analysis identified significantly lower levels of fecal thiamine in individuals with obesity (P_Wilcoxon < 0.001). …”

Data Sheet 1_Multi-omics analyses reveal altered gut microbial thiamine production in obesity.pdf by Yu Xia (8822)

“…</p>Results<p>Metabolomic analysis identified significantly lower levels of fecal thiamine in individuals with obesity (P_Wilcoxon < 0.001). …”

Down-Regulation of Annexin A Proteins in Human Mesangial Cells by TEGDMA and Bis-GMA Treatment Disrupts Proteins Involved in Cellular Function by Ayse Nur Dogan (21015836)

“…Transient knockdown of annexin A2 protein expression using annexin A2 siRNA resulted in a significant decrease in alpha smooth muscle actin and non-muscle myosin protein expression in human mesangial cells when compared to cells transfected with non-targeting control siRNA. …”

Data Sheet 1_Global trends in refractive disorders from 1990 to 2021: insights from the global burden of disease study and predictive modeling.csv by Lihong Huang (1346928)

“…Notably, both the prevalence and DALYs associated with refractive disorders decreased significantly in the 60 to 64 age group. …”

Table 1_Global trends in refractive disorders from 1990 to 2021: insights from the global burden of disease study and predictive modeling.xlsx by Lihong Huang (1346928)

“…Notably, both the prevalence and DALYs associated with refractive disorders decreased significantly in the 60 to 64 age group. …”

Table 2_Global trends in refractive disorders from 1990 to 2021: insights from the global burden of disease study and predictive modeling.xlsx by Lihong Huang (1346928)

“…Notably, both the prevalence and DALYs associated with refractive disorders decreased significantly in the 60 to 64 age group. …”

Data Sheet 2_Global trends in refractive disorders from 1990 to 2021: insights from the global burden of disease study and predictive modeling.csv by Lihong Huang (1346928)

“…Notably, both the prevalence and DALYs associated with refractive disorders decreased significantly in the 60 to 64 age group. …”

Data Sheet 1_Dynamic electrophysiological changes in abnormal brain cavities post-ischemic stroke.docx by Ugur Kilic (9927866)

“…We observed significant decreases in power across different conditions (p < 0.0001), and this decrease varied in different locations. …”