Showing 1,041 - 1,060 results of 1,354 for search '(( significant decrease decrease ) OR ( significantly impaired decrease ))~', query time: 0.34s Refine Results
  1. 1041

    Data Sheet 1_The effects of sleep deprivation on cognitive flexibility: a scoping review of outcomes and biological mechanisms.docx by Xuefeng Sun (408801)

    Published 2025
    “…The primary biological mechanisms involve decreased cerebral oxygen supply, impaired cerebrovascular reactivity, and alterations in gene expression and hormone levels. …”
  2. 1042

    Table 1_Identification of two KPC variants, KPC-204 and KPC-227, in ST11-K64 Klebsiella pneumoniae during prolonged hospitalization of a single patient.docx by Shijun Sun (9287651)

    Published 2025
    “…Molecular docking analyses revealed that the D179Y mutation impaired meropenem hydrolysis by decreasing binding affinity. …”
  3. 1043

    Table 1_Exploring the role of LOX family in glioma progression and immune modulation.docx by Chen Liu (75209)

    Published 2025
    “…LOX expression correlated with increased infiltration of macrophages and eosinophils and decreased presence of Treg and CD8+ T cells. Knockdown of LOX genes impaired glioma cell functions, induced apoptosis, and altered immune cell behavior by reducing M2 macrophage polarization and enhancing CD8+ T cell activity.…”
  4. 1044

    Image 1_Exploring the role of LOX family in glioma progression and immune modulation.jpeg by Chen Liu (75209)

    Published 2025
    “…LOX expression correlated with increased infiltration of macrophages and eosinophils and decreased presence of Treg and CD8+ T cells. Knockdown of LOX genes impaired glioma cell functions, induced apoptosis, and altered immune cell behavior by reducing M2 macrophage polarization and enhancing CD8+ T cell activity.…”
  5. 1045

    The quality metrics of 4C-seq data. by Tingting Jiang (169999)

    Published 2025
    “…Functional assays demonstrated that targeted repression of Pparα-En4 region significantly decreased <i><i>Ppar</i>α</i> expression and impaired brown adipocyte differentiation and thermogenesis. …”
  6. 1046

    <i>Edwardsiella piscicida</i> employs C3 derivative to mediate internalization and infection via the teleost-specific receptor by Mo-Fei Li (21624535)

    Published 2025
    “…When PoCD18 was knocked down or blocked, bacterial infection and tissue lesions were significantly decreased. Mechanistically, the intracellular domain of PoCD18 subsequently interacted with PoCytohesin and triggered the phosphorylation of the phosphatidylinositol 3-kinase (PI3K)/serine-threonine protein kinase (Akt) signalling pathway. …”
  7. 1047

    Table 1_Speckle tracking technology and investigation of risk factors for premature ventricular contraction-induced cardiomyopathy.pdf by Qiao Ma (136536)

    Published 2025
    “…Regression analysis revealed that asymptomatic PVCs, paired/interpolated PVCs, wide QRS duration (≥150 ms), and higher PVC burden were significantly associated with decreased GLS and GCS magnitude. …”
  8. 1048

    Uncropped western blot images. by Tingting Jiang (169999)

    Published 2025
    “…Functional assays demonstrated that targeted repression of Pparα-En4 region significantly decreased <i><i>Ppar</i>α</i> expression and impaired brown adipocyte differentiation and thermogenesis. …”
  9. 1049

    <b><i>Escherichia coli α-hemolysin induces red blood cell retention in a microfluidic spleen-like device</i></b> by Nicolas Saffioti (9965939)

    Published 2025
    “…</p><p dir="ltr">In the first device, which mimics the mechanical deformation of RBCs in narrow capillaries, HlyA sublytic concentrations were found to significantly impair RBC deformability. These changes were accompanied by an increase in cytosolic Ca<sup>2+</sup> and volume expansion. …”
  10. 1050

    Table 4_Speckle tracking technology and investigation of risk factors for premature ventricular contraction-induced cardiomyopathy.pdf by Qiao Ma (136536)

    Published 2025
    “…Regression analysis revealed that asymptomatic PVCs, paired/interpolated PVCs, wide QRS duration (≥150 ms), and higher PVC burden were significantly associated with decreased GLS and GCS magnitude. …”
  11. 1051

    Table 3_Speckle tracking technology and investigation of risk factors for premature ventricular contraction-induced cardiomyopathy.pdf by Qiao Ma (136536)

    Published 2025
    “…Regression analysis revealed that asymptomatic PVCs, paired/interpolated PVCs, wide QRS duration (≥150 ms), and higher PVC burden were significantly associated with decreased GLS and GCS magnitude. …”
  12. 1052

    Table 5_Speckle tracking technology and investigation of risk factors for premature ventricular contraction-induced cardiomyopathy.pdf by Qiao Ma (136536)

    Published 2025
    “…Regression analysis revealed that asymptomatic PVCs, paired/interpolated PVCs, wide QRS duration (≥150 ms), and higher PVC burden were significantly associated with decreased GLS and GCS magnitude. …”
  13. 1053

    The values used to build graphs in the paper. by Tingting Jiang (169999)

    Published 2025
    “…Functional assays demonstrated that targeted repression of Pparα-En4 region significantly decreased <i><i>Ppar</i>α</i> expression and impaired brown adipocyte differentiation and thermogenesis. …”
  14. 1054

    Table 1_ADAM8 in macrophages exacerbates sepsis-induced cardiomyopathy by impeding efferocytosis.docx by Zhenjun Ji (11050644)

    Published 2025
    “…</p>Results<p>Here, we demonstrate that ADAM8 expression is significantly upregulated in cardiac macrophages of SICM mice using single-cell transcriptomics and immunofluorescence. …”
  15. 1055

    The PCR primers of constructed vectors. by Tingting Jiang (169999)

    Published 2025
    “…Functional assays demonstrated that targeted repression of Pparα-En4 region significantly decreased <i><i>Ppar</i>α</i> expression and impaired brown adipocyte differentiation and thermogenesis. …”
  16. 1056

    Table 2_Speckle tracking technology and investigation of risk factors for premature ventricular contraction-induced cardiomyopathy.pdf by Qiao Ma (136536)

    Published 2025
    “…Regression analysis revealed that asymptomatic PVCs, paired/interpolated PVCs, wide QRS duration (≥150 ms), and higher PVC burden were significantly associated with decreased GLS and GCS magnitude. …”
  17. 1057

    DataSheet1_Clinical associations of complement-activating collectins, collectin-10, collectin-11 and mannose-binding lectin in preterm neonates.pdf by Gabriela Gajek (4060549)

    Published 2024
    “…</p>Findings<p>Low concentrations of CL-10 in cord sera (<462 ng/ml corresponding to the 10<sup>th</sup> percentile) were significantly associated with births at GA ≤32 weeks. …”
  18. 1058

    <b>Role of the Chaperone ClpB in</b><b> </b><b>Mycoplasma bovis</b><b> Virulence: Implications for </b><b>stress response, a</b><b>dhesion, </b><b>b</b><b>iofilm </b><b>d</b><b>eve... by Hui zhang (22187170)

    Published 2025
    “…Phenotypic characterization revealed that ClpB disruption attenuated key virulence attributes, including: impaired host cell adhesion capacity, significant reduction in biofilm formation (p<0.01), diminished induction of proinflammatory cytokines (IL-1β, IL-6, TNF-α) in infected BoMac cells, decreased extracellular nuclease activity. …”
  19. 1059

    Data Sheet 1_Andrographolide suppresses chondrosarcoma cell migration and invasion by inhibiting the PI3K/Akt/mTOR signaling pathway and activating autophagy.pdf by Chun-Fei Wu (22315444)

    Published 2025
    “…Wound healing and transwell assays demonstrated that Andro (5 and 20 μM) treatment significantly reduced the wound healing rate and impaired the migratory and invasive abilities of chondrosarcoma cells after 24 hours (p<0.05) compared to controls. …”
  20. 1060

    Table 1_Danggui Buxue Decoction attenuates 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone—induced lung cancer growth in A/J mice by suppressing HIF-1α/VEGF-mediated angiogenesis.do... by Wu Chen (569414)

    Published 2025
    “…By week 20, progressive multifocal opacities emerged alongside reduced pulmonary artery flow, impaired lung function, elevated TNF-α/VEGF, and decreased WBC, lymphocytes, and platelets. …”