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significantly impaired » significantly impairs (Expand Search), significantly improved (Expand Search), significantly improve (Expand Search)
significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
impaired decrease » marked decrease (Expand Search)
significantly impaired » significantly impairs (Expand Search), significantly improved (Expand Search), significantly improve (Expand Search)
significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
impaired decrease » marked decrease (Expand Search)
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1241
Table 1_Mechanism of Huaiqihuang (HQH) against cyclophosphamide (CYP)-induced hippocampal neurotoxicity based on network pharmacology, molecular docking and experimental verificati...
Published 2025“…Experimental validation using Western blot confirmed that HQH significantly decreased the protein expression of TNF, HSP90AA1, TP53, and MAPK1 in hippocampal tissues.…”
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1242
Table 2_Mechanism of Huaiqihuang (HQH) against cyclophosphamide (CYP)-induced hippocampal neurotoxicity based on network pharmacology, molecular docking and experimental verificati...
Published 2025“…Experimental validation using Western blot confirmed that HQH significantly decreased the protein expression of TNF, HSP90AA1, TP53, and MAPK1 in hippocampal tissues.…”
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1243
Table 4_Mechanism of Huaiqihuang (HQH) against cyclophosphamide (CYP)-induced hippocampal neurotoxicity based on network pharmacology, molecular docking and experimental verificati...
Published 2025“…Experimental validation using Western blot confirmed that HQH significantly decreased the protein expression of TNF, HSP90AA1, TP53, and MAPK1 in hippocampal tissues.…”
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1244
Data Sheet 1_Curcumin promotes spermatogenesis in mice with cryptorchidism by regulating testicular protein O-GlcNAcylation.docx
Published 2025“…Curcumin treatment mitigated these abnormalities, with the most significant improvement observed at a dosage of 100 mg/kg, without substantial adverse effects on other organs. …”
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1245
Data Sheet 1_Integrated transcriptome and co-expression network analysis revealed the molecular mechanism of cold tolerance in japonica rice at booting stage.zip
Published 2025“…</p>Results<p>The results demonstrated that cold stress significantly decreased yield traits, particularly seed-setting rate—a reliable cold tolerance indicator. …”
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1246
Table 1_Abnormal eye movements: relationship with clinical symptoms and predictive value for Alzheimer’s disease.docx
Published 2024“…Abnormal eye movements are significantly correlated with global cognition, multiple cognitive domains, and activities of daily living. …”
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1247
The effect of G83R mutation on transthyretin protein structural stability
Published 2024“…In the thermodynamic stability, the quaternary and tertiary structural stability of TTR G83R is lower than wild-type TTR but significantly higher than TTR V30M. The fibril formation rate of TTR G83R under acidic conditions was between that of wild-type TTR and V30M variants. …”
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1248
Data Sheet 1_The relationship between hearing loss and frailty in older adults at risk of cognitive decline: a cross-sectional study.pdf
Published 2025“…Objectives<p>To investigate the association between hearing loss and frailty among a group of older community volunteers with mild cognitive impairment.</p>Design<p>This study recruited 162 older community volunteers who have mild cognitive impairment and symmetric age-related hearing loss. …”
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1249
Table 1_Exogenous myo-inositol enhances drought tolerance in maize seedlings by antioxidant defense, and photosynthetic efficiency.docx
Published 2025“…Introduction<p>Drought stress severely impairs maize (Zea mays L.) production, particularly during the seedling stage.…”
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1250
Table 1_Evaluation of mesenchymal stem cells as an in vitro model for inherited retinal diseases.docx
Published 2024“…Compared to the popular iPSCs, for example, MSC-based models are significantly cheaper and faster to obtain, making them more feasible for large-scale drug screening. …”
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1251
Supplementary file 2_Immune indicators as predictors of cancer-related fatigue: a risk prediction model in pan-cancer patients.docx
Published 2025“…Background<p>Cancer‐related fatigue (CRF) is a prevalent and multifactorial symptom that significantly impairs the quality of life in cancer patients. …”
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1252
Supplementary file 1_Immune indicators as predictors of cancer-related fatigue: a risk prediction model in pan-cancer patients.docx
Published 2025“…Background<p>Cancer‐related fatigue (CRF) is a prevalent and multifactorial symptom that significantly impairs the quality of life in cancer patients. …”
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1253
Table 1_Alterations in gut–kidney axis indicators and TMAO-related biomarkers in elderly patients with hypertensive nephropathy.xlsx
Published 2025“…</p>Results<p>The chronic kidney disease group exhibited elevated serum urea and creatinine and reduced eGFR, along with increased levels of KIM-1, NGAL, IL-18, TNF-α, IL-6, NF-κB, and FMO3. Urinary TMAO was significantly decreased in both hypertensive groups, while serum TMAO remained unchanged. …”
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1254
Data Sheet 1_Lipopolysaccharide affects metabolic processes and energy homeostasis in the corpus luteum.xlsx
Published 2025“…Introduction<p>Chronic inflammation caused by Escherichia coli infections has a significant negative impact on the reproductive system and impairs fertility. …”
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1255
Image 1_Cerebellar microstructural and functional connectivity changes in patients with neuromyelitis optica spectrum disorders and their correlation with cognitive function: a fem...
Published 2025“…</p>Results<p>Patients exhibited significant cerebellar alterations, including GMV reduction in bilateral lobules VI/VIII and the vermis, decreased fractional anisotropy in Crus I, and altered FC between Crus I and occipital/frontal regions. …”
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1256
Table 2_Analysis of risk factors in breast cancer patients with hand-foot syndrome and oral mucositis caused by pegylated liposomal doxorubicin.doc
Published 2025“…However, PLD is associated with adverse reactions (ADRs) such as hand-foot syndrome (HFS) and oral mucositis (OM), which have garnered significant attention. Although not life-threatening, HFS and OM can cause severe discomfort and functional impairment. …”
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1257
Data Sheet 2_Metabolomics reveals key biomarkers for ischemic stroke: a systematic review of emerging evidence.pdf
Published 2025“…Glycine-serine-threonine and valine-leucine-isoleucine pathways were significant in diagnosing IS and AIS, and in differentiating ischemic and hemorrhagic strokes, as well as identifying post-stroke depression and cognitive impairment.…”
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1258
Data Sheet 1_Metabolomics reveals key biomarkers for ischemic stroke: a systematic review of emerging evidence.pdf
Published 2025“…Glycine-serine-threonine and valine-leucine-isoleucine pathways were significant in diagnosing IS and AIS, and in differentiating ischemic and hemorrhagic strokes, as well as identifying post-stroke depression and cognitive impairment.…”
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1259
Table_3_Combinatorial protection of cochlear hair cells: not too little but not too much.docx
Published 2024“…They also suggest that inhibiting too many biological processes impairs functions critical to HC survival, resulting in decreased protection.…”
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1260
Data Sheet 3_Metabolomics reveals key biomarkers for ischemic stroke: a systematic review of emerging evidence.pdf
Published 2025“…Glycine-serine-threonine and valine-leucine-isoleucine pathways were significant in diagnosing IS and AIS, and in differentiating ischemic and hemorrhagic strokes, as well as identifying post-stroke depression and cognitive impairment.…”