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20641
Drug-Free Mesoporous Silica Nanoparticles Enable Suppression of Cancer Metastasis and Confer Survival Advantages to Mice with Tumor Xenografts
Published 2024“…In vivo studies showed that overall tumor metastasis decreased in 4T1 xenografts mice treated with MSN-PEG/TA 25 with a notable reduction in lung tumor metastasis. …”
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20642
Data Sheet 1_Identification of a multiple DAMP scavenger mimicking the DAMP-binding site of TLR4 to ameliorate lethal sepsis.pdf
Published 2025“…Additionally, OP18-treated septic mice demonstrated reduced blood organ injury markers, decreased proinflammatory cytokine levels, attenuated ALI, and improved survival. …”
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20643
Data Sheet 2_Aurantii Fructus extract alleviates DSS-induced colitis in mice via regulating NF-κB and Nrf2/HO-1 signaling pathways and modulating intestinal microbiota.zip
Published 2025“…Concurrently, AFE enhanced antioxidant capacity by increasing glutathione (GSH) levels, decreasing malondialdehyde (MDA), and activating the Nrf2/HO-1 signaling pathway. …”
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20644
Data Sheet 1_Identification of novel gut microbiota-related biomarkers in cerebral hemorrhagic stroke.zip
Published 2025“…Machine learning identified four hub genes—LEF1, ITGAX, BLVRB, and ATF4. All were significantly upregulated in ICH tissues and plasma, correlating with immune cell infiltration. …”
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20645
Migration and attacking prey.
Published 2025“…<div><p>Recent research has concentrated on emphasizing the significance of incorporating renewable distributed generations (RDGs), like photovoltaic (PV) and wind turbines (WTs), into the distribution system to address issues related to distributed generation (DG) allocation. …”
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20646
Image 3_StACS3-mediated drought stress adaptation in potato involves interactions with StPP2C2 and St14-3-3 proteins.tiff
Published 2025“…In contrast, silencing StACS3 significantly reduces stress-induced ethylene accumulation and enhances drought resilience, including decreased cell death and increased antioxidant activity. …”
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20647
Data Sheet 1_Differential concentrations of NaCl and K2Cr2O7 stress conditions: biophoton characteristics and quality prediction feasibility analysis of fresh Nepeta cataria L. lea...
Published 2025“…For instance, in the 120 mmol/L NaCl group, the CPS decreased by 54.27%, while I<sub>0</sub> dropped by 54.12%. …”
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20648
Data Sheet 1_Trends in adolescent pertussis burden: a systematic analysis from 1990 to 2021 in global, regional, and national within the global burden of disease study 2021, with f...
Published 2025“…However, in Central Sub-Saharan Africa, the number of prevalence cases, incidence cases, deaths, and DALYs have increased, while these values have significantly decreased among adolescents in the other 20 GBD regions. …”
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20649
Table 9_Integrative bulk and single-cell transcriptome analyses reveal integrated stress response-related biomarkers in periodontitis with experimental validation.xlsx
Published 2025“…RT-qPCR results confirmed that the expression levels of BTG2, DERL3, FOS, and HSPA13 were significantly upregulated, while YOD1 expression was downregulated in the PD group (P < 0.05), which was consistent with the database-predicted patterns.…”
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20650
Data Sheet 1_Biological mechanisms of sodium nitroprusside in enhancing quality of Radix Paeoniae Rubra and Radix Paeoniae Alba.docx
Published 2025“…Moreover, experiments involving combined treatment with SNP and ROS scavengers demonstrated that ROS act as the key mediator linking exogenous NO to the secondary metabolism of P. lactiflora: scavenging ROS significantly attenuated the SNP-induced accumulation of target secondary metabolites.…”
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20651
Image 11_Potential marker genes for psoriasis revealed based on single-cell sequencing and Mendelian randomization analysis.tif
Published 2025“…</p>Results<p>Seven genetically informed candidate genes were identified as being significantly associated with psoriasis susceptibility. …”
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20652
Table 6_Integrative bulk and single-cell transcriptome analyses reveal integrated stress response-related biomarkers in periodontitis with experimental validation.xlsx
Published 2025“…RT-qPCR results confirmed that the expression levels of BTG2, DERL3, FOS, and HSPA13 were significantly upregulated, while YOD1 expression was downregulated in the PD group (P < 0.05), which was consistent with the database-predicted patterns.…”
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20653
Description of the behaviour of GWO.
Published 2025“…<div><p>Recent research has concentrated on emphasizing the significance of incorporating renewable distributed generations (RDGs), like photovoltaic (PV) and wind turbines (WTs), into the distribution system to address issues related to distributed generation (DG) allocation. …”
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20654
Data Sheet 5_StACS3-mediated drought stress adaptation in potato involves interactions with StPP2C2 and St14-3-3 proteins.pdf
Published 2025“…In contrast, silencing StACS3 significantly reduces stress-induced ethylene accumulation and enhances drought resilience, including decreased cell death and increased antioxidant activity. …”
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20655
Image 3_Potential marker genes for psoriasis revealed based on single-cell sequencing and Mendelian randomization analysis.tif
Published 2025“…</p>Results<p>Seven genetically informed candidate genes were identified as being significantly associated with psoriasis susceptibility. …”
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20656
Image 2_Immunological reference intervals in pregnancy: longitudinal analysis of adaptive lymphocyte subsets.tif
Published 2025“…</p>Results<p>Pregnancy was associated with decreased total B cell counts, particularly within transitional and anergic naïve subsets, and increased activated naïve and memory B cells. …”
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20657
Characteristics of specialists at day centers.
Published 2025“…The intervention group showed significantly reduced weight (median; baseline 1, post-intervention 0.975, follow-up 0.983, p < 0.001), and slightly reduced waist circumference (median; baseline 1, post-intervention 0.975, follow-up 0.975, p = 0.226); however, the control group showed no change. …”
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20658
Table 2_Association between DASH diet and metabolic syndrome in US adults: a cross-sectional study.xlsx
Published 2025“…The proportion of women, younger individuals, non-Hispanic Blacks, low-income individuals, smokers, and those with MetS gradually decreased from Q1 to Q5 quintile groups. After adjusting for all variables, the odds ratio of MetS risk in the highest DASH quintile (Q5) compared with the lowest (Q1) was 0.60 (0.48, 0.77). …”
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20659
Increased COX6A2 promotes pancreatic β-cell apoptosis and is suppressed in diabetic GK rats after Roux-en-Y gastric bypass
Published 2024“…We found that RYGB significantly reduced β-cell apoptosis, accompanied by decreased COX6A2 expression in islets from diabetic Goto-Kakizaki (GK) rats. …”
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20660
Table 1_Characteristics and trends of unintentional injuries among children and adolescents in Kunshan, China: a hospital-based retrospective study, 2018–2023.docx
Published 2025“…Unintentional injury cases decreased significantly during COVID-19 (2020–2022). …”