Image 1_Efficacy and safety of tocilizumab in managing cytokine release syndrome after CD19 CAR-T therapy for relapsed or refractory B-cell acute lymphoblastic leukemia.tiff by Qianyi Zhou (6196383)

“…Additionally, 10 patients showed decreased cytokine levels.Importantly, tocilizumab did not impair CAR-T cell expansion or efficacy, nor did it increase the incidence of adverse events.…”

Data Sheet 1_Reduction of orexin-expressing neurons and a unique sleep phenotype in the Tg-SwDI mouse model of Alzheimer’s disease.pdf by Yan Wu (70890)

“…The apoptotic cell death marker cleaved caspase-3 immunoreactive (Caspase-3-IR) percentage in orexin-IR neurons was significantly higher in Tg-SwDI mice than in WT controls. …”

Functional assays of neurotoxicity testing of α-terpineol in Wistar rats by Sneha Suma Hegde (19856407)

“…The research found that exposure to α- terpineol led to several adverse effects, such as reduced body weight, impaired motor coordination, and significant declines in sperm parameters and testosterone levels. …”

Supplementary Material for: Fibrillin-1 deficiency perturbs aortic cholinergic relaxation and adrenergic contraction in a mouse model of early onset progressively severe Marfan syn... by Cantalupo A. (20574239)

“…Results: Isometric force measurements of aortic rings from 16-day-old male Fbn1mgR/mgR mice revealed a significant reduction in acetylcholine (ACh)-induced relaxation and increased phenylephrine (PE)-promoted contractility, associated with abnormally low eNOSSer1177 phosphorylation, decreased NO production and augmented superoxide levels. …”

DataSheet1_Clinical associations of complement-activating collectins, collectin-10, collectin-11 and mannose-binding lectin in preterm neonates.pdf by Gabriela Gajek (4060549)

“…</p>Findings<p>Low concentrations of CL-10 in cord sera (<462 ng/ml corresponding to the 10^th percentile) were significantly associated with births at GA ≤32 weeks. …”

Data Sheet 1_Andrographolide suppresses chondrosarcoma cell migration and invasion by inhibiting the PI3K/Akt/mTOR signaling pathway and activating autophagy.pdf by Chun-Fei Wu (22315444)

“…Wound healing and transwell assays demonstrated that Andro (5 and 20 μM) treatment significantly reduced the wound healing rate and impaired the migratory and invasive abilities of chondrosarcoma cells after 24 hours (p<0.05) compared to controls. …”

Table 1_Danggui Buxue Decoction attenuates 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone—induced lung cancer growth in A/J mice by suppressing HIF-1α/VEGF-mediated angiogenesis.do... by Wu Chen (569414)

“…By week 20, progressive multifocal opacities emerged alongside reduced pulmonary artery flow, impaired lung function, elevated TNF-α/VEGF, and decreased WBC, lymphocytes, and platelets. …”

Supplementary file 1_Mechanism of soil microbial community degradation under long-term tomato monoculture in greenhouse.docx by Menglu Li (4458208)

“…<p>Tomato (Solanum lycopersicum L.), an economically significant crop, is frequently cultivated in greenhouses under continuous monoculture systems. …”

Table 1_Unveiling neuroimmunology profile of immunological non-responders in HIV: a multimodal MRI approach.docx by Yang Zhang (30734)

“…Furthermore, INRs exhibited significant alterations in functional connectivity in the temporal and occipital gyrus. …”

qorA associated data by fengning chen (20930834)

“…Notably, the <i>qorA</i> mutant exhibited impaired survival against neutrophil killing as well as reduced viability in human blood, plasma, and during mouse bloodstream infections, along with a significant decline in its anti-phagocytic capability. …”

Development and validation of an ultra-performance liquid chromatography with tandem mass spectrometry method for determination of soluble repulsive guidance molecule A in human se... by Patrick Schreier (19829972)

“…</p> <p>In CSF from patients with MCI and those with AD, total soluble RGMa was significantly decreasing to a median of 22.6 and 21.4 ng/ml, respectively.…”

Low temperature reduces byssus adhesion of highly invasive golden mussels: Influencing mechanisms and antifouling implications by Miaolian Zhang (21974951)

“…Our results showed that low-temperature exposures significantly reduced adhesion rates of golden mussels, primarily by limiting byssus production associated with impaired synthesis and secretion of byssal proteins and decreasing byssus breaking force. …”

Semaglutide ameliorates diabetes-associated cognitive dysfunction in mouse model of type 2 diabetes by Yan Zhu (112437)

“…<p dir="ltr"><b>Background:</b> Type 2 diabetes mellitus (T2DM) is associated with cognitive dysfunction, which significantly impacts the quality of life. Semaglutide, a glucagon-like peptide-1 (GLP-1) receptor agonist, has shown potential neuroprotective effects. …”

Supplementary Material for: Bidirectional Impact of Varying Severity of Acute Kidney Injury on Calcium Oxalate Stone Formation by Yang Y. (3237684)

“…Transcriptomic analysis revealed that genes associated with inflammation and cell adhesion pathways were significantly upregulated after severe AKI, while genes related to energy metabolism pathways were significantly upregulated after mild AKI. …”

Supplementary Material for: Pharmacokinetic Properties of Dapagliflozin in Patients with Stage 4 Chronic Kidney Disease by figshare admin karger (2628495)

“…In conclusion, no clinically significant accumulation of dapagliflozin was observed in patients with stage 4 CKD.…”

Table 1_Evaluation of IVIM and FACT imaging for early detection of rotator cuff muscle degeneration and physiotherapy exercise effects.docx by Ling Teng (317759)

“…Additionally, the change in D* and f correlated with CS, ASES scores and VAS scores respectively. FF showed a decreasing trend but lacking significance (p > 0.05).…”

Table 1_Comparative study of brain activity and functional connectivity in blepharospasm and blepharospasm-oromandibular dystonia.doc by Yanying Wang (1615096)

“…Clinical scores of BSP severity were significantly correlated with dALFF in some of these important regions.…”

Table 1_Multi-omics-based phenotyping of AFG3L2-mutant lymphoblasts determines key factors of a pathophysiological interplay between mitochondrial vulnerability and neurodegenerati... by Menekse Oeztuerk (20756606)

“…Our proteomic analysis revealed AFG3L2 impairment, with significant dysregulation of proteins critical for mitochondrial function, cytoskeletal integrity, and cellular metabolism. …”

Image 1_Multi-omics-based phenotyping of AFG3L2-mutant lymphoblasts determines key factors of a pathophysiological interplay between mitochondrial vulnerability and neurodegenerati... by Menekse Oeztuerk (20756606)

“…Our proteomic analysis revealed AFG3L2 impairment, with significant dysregulation of proteins critical for mitochondrial function, cytoskeletal integrity, and cellular metabolism. …”

<b>Canagliflozin-induced adaptive metabolism in bone</b> by Sher Bahadur Poudel (20686192)

“…Beyond this, these drugs induce various metabolic changes, including weight loss and impaired bone integrity. There is a significant gap in understanding SGLT2i-induced skeletal changes, as SGLT2 is not expressed in osteoblasts or osteocytes, which use glucose to remodel the bone matrix. …”