Data Sheet 1_A novel short-course, low-intensity blood-flow-restricted exercise (BFRE) regimen to study satellite cell function in critical illness survivors with sustained muscle... by Sunita Mathur (759075)

“…Introduction<p>ICU-acquired weakness (ICUAW) develops in critically ill patients and can persist after hospital discharge, resulting in physical disability. Decreased satellite cell content is reported in the atrophic muscle of critical illness survivors, suggesting that the sustained muscle wasting results from satellite cell dysfunction and impaired muscle regeneration. …”

Data Sheet 1_Curcumin promotes spermatogenesis in mice with cryptorchidism by regulating testicular protein O-GlcNAcylation.docx by Zhen Wang (72451)

“…Curcumin treatment mitigated these abnormalities, with the most significant improvement observed at a dosage of 100 mg/kg, without substantial adverse effects on other organs. …”

Glutamate dehydrogenase 2 is required for virulence by facilitating fungal growth in the host hemocoel by Yuzhen Lu (4402591)

“…Deletion of <i>MrGDH2</i> failed to alkalize amino acid-containing media under carbon deprivation, leading to impaired mycelia growth and conidiation. Hemolymph carbohydrates were decreased during <i>M. robertsii</i> infection, and the Δ<i>Mrgdh2</i> mutant exhibited delayed fungal growth and impaired alkalization in hemolymph cultures. …”

Data Sheet 1_Physical activity of moderate-intensity optimizes myocardial citrate cycle in a murine model of heart failure.pdf by Lucyna Widacha (20981330)

“…Interestingly, 8-sWR significantly decreased myocardial citrate content in the presence of unchanged myocardial [BCAAs], ETC proteins content and mtDNA copy number.…”

Impact of moderate-to-severe ulcerative colitis and Crohn’s disease on sexual activity: United States and European patient perspectives from the communicating needs and features of... by Marla C. Dubinsky (10978320)

“…Of these, most US (UC: 63%, CD: 69%) and European (UC: 53%, CD: 56%) patients reported avoiding or decreasing sexual activity due to UC or CD in the past 3 months; however, the proportion was significantly greater among US patients (<i>p</i> <.05). …”

PPFIA4 Knockdown Suppresses Expression, Proliferation, and Migration in Colorectal Cancer Cells. by Wenliang Yuan (7842908)

“…<p>(A) qPCR analysis showing a significant reduction in PPFIA4 mRNA expression in the si-PPFIA4 group.…”

Data Sheet 1_Integrated transcriptome and co-expression network analysis revealed the molecular mechanism of cold tolerance in japonica rice at booting stage.zip by Jiaqi Wang (369548)

“…</p>Results<p>The results demonstrated that cold stress significantly decreased yield traits, particularly seed-setting rate—a reliable cold tolerance indicator. …”

Table 1_Abnormal eye movements: relationship with clinical symptoms and predictive value for Alzheimer’s disease.docx by Jing Qi (235750)

“…Abnormal eye movements are significantly correlated with global cognition, multiple cognitive domains, and activities of daily living. …”

The effect of G83R mutation on transthyretin protein structural stability by Xingwang Chen (11225802)

“…In the thermodynamic stability, the quaternary and tertiary structural stability of TTR G83R is lower than wild-type TTR but significantly higher than TTR V30M. The fibril formation rate of TTR G83R under acidic conditions was between that of wild-type TTR and V30M variants. …”

Supplemental Materials by Ying Wang (15199117)

“…Compared to lean male mice, obese male mice had significantly increased accumulation of fluorescein-conjugated dextran in multiple organs, higher levels of soluble VE-cadherin, impaired systolic function with decreased ejection fraction post-AP and lipolysis. …”

Data Sheet 1_Endothelial Zmiz1 modulates developmental angiogenesis in the retina.pdf by Nehal R. Patel (18522672)

“…Inducible endothelial cell-specific ablation of Zmiz1 postnatally resulted in impaired retinal vascular outgrowth, decreased vascular density, and increased vessel regression. …”

<b><i>Escherichia coli α-hemolysin induces red blood cell retention in a microfluidic spleen-like device</i></b> by Nicolas Saffioti (9965939)

“…</p><p dir="ltr">In the first device, which mimics the mechanical deformation of RBCs in narrow capillaries, HlyA sublytic concentrations were found to significantly impair RBC deformability. These changes were accompanied by an increase in cytosolic Ca²⁺ and volume expansion. …”

Image 1_The role of E2F1 in promoting EIF4EBP1 transcription in cryptorchid mice: association with autophagy in germ cells.tif by Jianguo Zhang (6482)

“…E2F1 was identified as an upstream regulator of EIF4EBP1, with knockdown of E2F1 significantly decreasing EIF4EBP1 promoter activity and binding. …”

<b>Role of the Chaperone ClpB in</b><b> </b><b>Mycoplasma bovis</b><b> Virulence: Implications for </b><b>stress response, a</b><b>dhesion, </b><b>b</b><b>iofilm </b><b>d</b><b>eve... by Hui zhang (22187170)

“…Phenotypic characterization revealed that ClpB disruption attenuated key virulence attributes, including: impaired host cell adhesion capacity, significant reduction in biofilm formation (p<0.01), diminished induction of proinflammatory cytokines (IL-1β, IL-6, TNF-α) in infected BoMac cells, decreased extracellular nuclease activity. …”

Data Sheet 1_The relationship between hearing loss and frailty in older adults at risk of cognitive decline: a cross-sectional study.pdf by Rong Tian (397491)

“…Objectives<p>To investigate the association between hearing loss and frailty among a group of older community volunteers with mild cognitive impairment.</p>Design<p>This study recruited 162 older community volunteers who have mild cognitive impairment and symmetric age-related hearing loss. …”

Table 1_Evaluation of mesenchymal stem cells as an in vitro model for inherited retinal diseases.docx by Maria Dodina (20223012)

“…Compared to the popular iPSCs, for example, MSC-based models are significantly cheaper and faster to obtain, making them more feasible for large-scale drug screening. …”

Raw data WB.pdf by Grazia Serino (21164993)

“…Moreover, miR-369-3p significantly decreased the release of pro-inflammatory cytokine IL-8. …”

Table 2_The gut commensal Faecalibacterium hominis attenuates indole—AhR signaling and restores ASD—like behaviors with BTBR mice.xlsx by You Yu (2102071)

“…Oral administration of 4P-15 significantly reduced the intestinal levels of indole, indole-3-propionic acid (IPA), and indole-3-acetic acid (IAA), as well as the level of IPA in brain. …”

Table 1_The gut commensal Faecalibacterium hominis attenuates indole—AhR signaling and restores ASD—like behaviors with BTBR mice.xlsx by You Yu (2102071)

“…Oral administration of 4P-15 significantly reduced the intestinal levels of indole, indole-3-propionic acid (IPA), and indole-3-acetic acid (IAA), as well as the level of IPA in brain. …”

Table 1_Alterations in gut–kidney axis indicators and TMAO-related biomarkers in elderly patients with hypertensive nephropathy.xlsx by Ziyi Li (349831)

“…</p>Results<p>The chronic kidney disease group exhibited elevated serum urea and creatinine and reduced eGFR, along with increased levels of KIM-1, NGAL, IL-18, TNF-α, IL-6, NF-κB, and FMO3. Urinary TMAO was significantly decreased in both hypertensive groups, while serum TMAO remained unchanged. …”