يعرض 1,261 - 1,280 نتائج من 1,354 نتيجة بحث عن '(( significant decrease decrease ) OR ( significantly impairs decrease ))~', وقت الاستعلام: 0.32s تنقيح النتائج
  1. 1261

    Table 5_Interaction with IGF1 overrides ANXA2-mediated anti-inflammatory functions of IGFBP5 in vivo.docx حسب Yan Fan (575147)

    منشور في 2025
    "…Monocytes of adjuvant-induced arthritis rats and RA patients expressed less IGFBP5 than normal controls, but its blood levels increased significantly. Adipocytes secreted large amounts of IGFBP5. …"
  2. 1262

    Table 3_Interaction with IGF1 overrides ANXA2-mediated anti-inflammatory functions of IGFBP5 in vivo.xlsx حسب Yan Fan (575147)

    منشور في 2025
    "…Monocytes of adjuvant-induced arthritis rats and RA patients expressed less IGFBP5 than normal controls, but its blood levels increased significantly. Adipocytes secreted large amounts of IGFBP5. …"
  3. 1263

    Table 3_Elevated miR-17-5p facilitates mycobacterial immune evasion by targeting MAP3K2 in macrophages.doc حسب Md Shoykot Jahan (22776341)

    منشور في 2025
    "…Increased miR-17-5p suppressed MAP3K2 expression and attenuated MAPK signaling, reducing phosphorylation of ERK, JNK, and p38. This resulted in decreased production of inflammatory mediators (TNF-α, IL-6, IL-1β), reduced iNOS and ROS levels, and impaired bacterial clearance.…"
  4. 1264

    Image4_Neuroprotective effects of a novel peptide through the Rho-integrin-Tie2 and PI3K/Akt pathways in experimental autoimmune encephalomyelitis model.JPEG حسب Wen Zhou (49050)

    منشور في 2025
    "…</p>Results<p>The results showed that C16 significantly improved the clinical score and cortical somatosensory/motor evoked potential. …"
  5. 1265

    Image1_Neuroprotective effects of a novel peptide through the Rho-integrin-Tie2 and PI3K/Akt pathways in experimental autoimmune encephalomyelitis model.JPEG حسب Wen Zhou (49050)

    منشور في 2025
    "…</p>Results<p>The results showed that C16 significantly improved the clinical score and cortical somatosensory/motor evoked potential. …"
  6. 1266

    Table 2_Elevated miR-17-5p facilitates mycobacterial immune evasion by targeting MAP3K2 in macrophages.doc حسب Md Shoykot Jahan (22776341)

    منشور في 2025
    "…Increased miR-17-5p suppressed MAP3K2 expression and attenuated MAPK signaling, reducing phosphorylation of ERK, JNK, and p38. This resulted in decreased production of inflammatory mediators (TNF-α, IL-6, IL-1β), reduced iNOS and ROS levels, and impaired bacterial clearance.…"
  7. 1267

    Table 1_Interaction with IGF1 overrides ANXA2-mediated anti-inflammatory functions of IGFBP5 in vivo.docx حسب Yan Fan (575147)

    منشور في 2025
    "…Monocytes of adjuvant-induced arthritis rats and RA patients expressed less IGFBP5 than normal controls, but its blood levels increased significantly. Adipocytes secreted large amounts of IGFBP5. …"
  8. 1268

    Data Sheet 1_Wooden breast myopathy is characterized by satellite cell dysfunction and syndecan-4 shedding.pdf حسب Lucie Pejšková (20467025)

    منشور في 2024
    "…Syndecans (SDCs) act as communication bridges within the muscle microenvironment, regulating interactions with extracellular matrix components and contributing significantly to tissue repair and inflammation. Specifically, syndecan-4 (SDC4) is involved in muscle regeneration at multiple stages.…"
  9. 1269

    Table 2_Interaction with IGF1 overrides ANXA2-mediated anti-inflammatory functions of IGFBP5 in vivo.xlsx حسب Yan Fan (575147)

    منشور في 2025
    "…Monocytes of adjuvant-induced arthritis rats and RA patients expressed less IGFBP5 than normal controls, but its blood levels increased significantly. Adipocytes secreted large amounts of IGFBP5. …"
  10. 1270

    Image2_Neuroprotective effects of a novel peptide through the Rho-integrin-Tie2 and PI3K/Akt pathways in experimental autoimmune encephalomyelitis model.JPEG حسب Wen Zhou (49050)

    منشور في 2025
    "…</p>Results<p>The results showed that C16 significantly improved the clinical score and cortical somatosensory/motor evoked potential. …"
  11. 1271

    Image6_Neuroprotective effects of a novel peptide through the Rho-integrin-Tie2 and PI3K/Akt pathways in experimental autoimmune encephalomyelitis model.JPEG حسب Wen Zhou (49050)

    منشور في 2025
    "…</p>Results<p>The results showed that C16 significantly improved the clinical score and cortical somatosensory/motor evoked potential. …"
  12. 1272

    <b>Liraglutide treatment reverses unconventional cellular defects in induced pluripotent stem cell-derived β cells harboring a partially functional </b><b><i>WFS1</i></b><b> varian... حسب Silvia Torchio (611349)

    منشور في 2025
    "…Pancreatic β cells obtained from patient-derived induced Pluripotent Stem Cells (iPSCs) carrying this <i>WFS1 </i>variant exhibited reduced insulin processing and impaired secretory granule maturation, as evidenced by proinsulin accumulation and decreased prohormone convertase PC1/3. …"
  13. 1273

    Image 1_Elevated miR-17-5p facilitates mycobacterial immune evasion by targeting MAP3K2 in macrophages.jpeg حسب Md Shoykot Jahan (22776341)

    منشور في 2025
    "…Increased miR-17-5p suppressed MAP3K2 expression and attenuated MAPK signaling, reducing phosphorylation of ERK, JNK, and p38. This resulted in decreased production of inflammatory mediators (TNF-α, IL-6, IL-1β), reduced iNOS and ROS levels, and impaired bacterial clearance.…"
  14. 1274

    Supplementary file 1_ZnO nanoparticles induce acute arrhythmia and heart failure in mice by disturbing cardiac ion channels.pdf حسب Xuexue Liu (3271641)

    منشور في 2025
    "…Mechanistically, exposure to ZnO NPs did not significantly affect the IK1, but it markedly decreased I<sub>Na</sub> and I<sub>Ca−L</sub> currents, resulting in a reduced amplitude and shortened duration of the action potential in cardiomyocytes. …"
  15. 1275

    Image3_Neuroprotective effects of a novel peptide through the Rho-integrin-Tie2 and PI3K/Akt pathways in experimental autoimmune encephalomyelitis model.TIF حسب Wen Zhou (49050)

    منشور في 2025
    "…</p>Results<p>The results showed that C16 significantly improved the clinical score and cortical somatosensory/motor evoked potential. …"
  16. 1276

    Image7_Neuroprotective effects of a novel peptide through the Rho-integrin-Tie2 and PI3K/Akt pathways in experimental autoimmune encephalomyelitis model.JPEG حسب Wen Zhou (49050)

    منشور في 2025
    "…</p>Results<p>The results showed that C16 significantly improved the clinical score and cortical somatosensory/motor evoked potential. …"
  17. 1277

    Image9_Neuroprotective effects of a novel peptide through the Rho-integrin-Tie2 and PI3K/Akt pathways in experimental autoimmune encephalomyelitis model.JPEG حسب Wen Zhou (49050)

    منشور في 2025
    "…</p>Results<p>The results showed that C16 significantly improved the clinical score and cortical somatosensory/motor evoked potential. …"
  18. 1278

    Mass spectrometry of Pparα-En4 pulldown proteins. حسب Tingting Jiang (169999)

    منشور في 2025
    "…Functional assays demonstrated that targeted repression of Pparα-En4 region significantly decreased <i><i>Ppar</i>α</i> expression and impaired brown adipocyte differentiation and thermogenesis. …"
  19. 1279

    <i>Irresistible</i><sup><i>p173</i></sup> is an allele of the Cadherin-encoding gene <i>cdh16.</i> حسب Susannah S. Schloss (21238775)

    منشور في 2025
    "…<b>(D)</b> <i>cdh16</i><sup><i>co79</i></sup> mutants (<i>n</i> = 39) have significantly impaired habituation (****<i>p</i> < 0.0001, Mann–Whitney test) compared to siblings (<i>n</i> = 32). …"
  20. 1280

    Table 1_Integrated physiological and transcriptomic analyses elucidate the molecular mechanisms of exogenous melatonin-mediated salt tolerance in pomegranate (Punica granatum L.).x... حسب Yuanling Yang (22524785)

    منشور في 2025
    "…Concurrently, salt stress severely impaired photosynthetic performance: PSII maximum photochemical efficiency (F<sub>V</sub>/F<sub>M</sub>) decreased by 44.5%, actual photochemical efficiency (Y<sub>II</sub>) and photochemical quenching (qP) were reduced, and non-photochemical quenching (NPQ) increased, indicating serious photoinhibition and energy wastage. …"