Data Sheet 1_Danqi soft caspule alleviates myocardial ischemia-reperfusion injury induced cardiomyocyte apoptosis by attenuating mitochondrial fission.docx by Ye Yang (297214)

“…Background<p>Myocardial ischemia-reperfusion (I/R) injury which leads to continuously worsening ventricular remodeling and cardiac dysfunction in the chronic stage, is a significant contributor to the global prevalence of heart failure. …”

DPOAE differences (in dB SPL), delayed observation minus baseline, as a function of the F2 frequency. by Eddy Fortier (20577301)

“…For each participant, graphs on the top row are for the left ear, while graphs on the bottom row are for the right ear. Significant amplitude decreases [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0309513#pone.0309513.ref049" target="_blank">49</a>] are highlighted with a red background. …”

Table 2_Human umbilical cord mesenchymal stem cells recover chemotherapy-induced premature ovarian failure.xlsx by Guojie Ji (21518650)

“…</p>Results<p>After hUC-MSCs therapy, the number of follicles recovered significantly and the atretic follicles decreased significantly. …”

Video 4_Ozone promotes macrophage efferocytosis and alleviates neuropathic pain by activating the AMPK/Gas6-MerTK/SOCS3 signaling pathway.mp4 by Shirong Ruan (15414081)

“…</p>Results<p>We found ozone at a concentration of 30μg significantly alleviated mechanical hypersensitivity in CCI mice and ozone significantly upregulates the phagocytic activity of BMDM. …”

<b>Differential Effects of Retinol-Binding Protein 3 and Anti-VEGF Antibodies on Retinal Dysfunctions in Diabetic Retinopathy</b> by Qin Li (36669)

“…<p dir="ltr">Anti-vascular endothelial growth factor (anti-VEGF) therapies are effective treatment of severe diabetic retinopathy (DR) and macular edema, but a significant subset of people showed inadequate response to anti-VEGF intervention. …”

Table 2_Evaluating treatment and care outcomes for neuromuscular diseases in a pediatric intermediate care setting.docx by Giacomo Brisca (10963929)

“…The majority of admissions were due to neurological issues (39.7%) and respiratory complications (22%), with a significant proportion of patients requiring initiation or potentiation of respiratory support (59%). …”

Data Sheet 2_Genome-wide identification of GDPD gene family in foxtail millet (Setaria italica L.) and functional characterization of SiGDPD14 under low phosphorus stress.docx by Chaomin Meng (21496829)

“…Under low phosphorus stress, the expression levels of SiGDPD3 and SiGDPD14 significantly increased, while SiGDPD1, SiGDPD5, SiGDPD6, and SiGDPD11 showed significant decreases.To identify the function of SiGDPD14, an over-expressed transgenic Arabidopsis was generated. …”

Table 4_Circulating growth differentiation factor-15 concentration and hypertension risk: a dose-response meta-analysis.docx by Zhengqing Yu (12641890)

“…Significant heterogeneity was detected in the pooled analysis and meta-regression analysis suggested that participants’ age and the prevalence of diabetes significantly accounted for the heterogeneity.…”

Non-linear associations between serum manganese with chronic kidney disease: results from two nationwide studies in the United States and China by Jiliang Zhang (1500367)

“…</p> <p>The higher Mn concentration was significantly associated with a lower prevalence of CKD through different non-linear patterns.…”

Data_Sheet_1_Effects of stand age and soil microbial communities on soil respiration throughout the growth cycle of poplar plantations in northeastern China.pdf by Xiangrong Liu (380124)

“…As stand age increased, Rs showed a significant decreasing trend. We further identified r-selected microbial communities (copiotrophic species) as key biological factors influencing the decline in Rs with increasing stand age. …”

Supplementary file 1_Assessment of suitability evaluation for Ficus altissima blume ancient trees in different climatic environments in Guangxi, China.docx by Hongliang Gu (21671054)

“…Introduction<p>The Guangxi Zhuang Autonomous Region of China is home to numerous Ficus altissima Blume (F. altissima) ancient trees over 300 years old, which hold significant cultural, ecological, and scientific research value. …”

Table 3_Proteomic profiling of peripheral blood mononuclear cells reveals immune dysregulation and metabolic alterations in kidney transplant recipients with COVID-19.xlsx by Giuseppe G. F. Leite (18186056)

“…<p>The COVID-19 pandemic has significantly impacted global health, especially in vulnerable populations like kidney transplant recipients (KTRs). …”

Data Sheet 3_Duodenal obstruction due to two congenital bands: a case report and literature review.pdf by Shiqiu Xiong (238109)

“…Physical examination revealed abdominal tenderness and decreased bowel sounds. Contrast x-ray showed an obstructed passage of contrast through the third part of the duodenum. …”

Table 1_5-deoxy-rutaecarpine protects against LPS-induced acute lung injury via inhibiting NLRP3 inflammasome-related inflammation.docx by Jinque Luo (9645983)

“…Introduction<p>Acute lung injury (ALI) induced by lipopolysaccharide (LPS) is a significant medical condition characterized by severe pulmonary inflammation and tissue damage. …”

Image 5_Moderate regular physical exercise can help in alleviating the systemic impact of schistosomiasis infection on brain cognitive function.tiff by Inssaf Berkiks (15350248)

“…Remarkably, exercise decreased glial cell production of TNFα, suggesting a shift towards a less pro-inflammatory environment. …”

Image 1_Exercise intolerance in patients with chronic coronary syndrome: insights from exercise stress echocardiography.tiff by Wei-wei Zhu (20349897)

“…An elevated peak EDVi/E/e’ and a decreased ΔSVi are independent risk factors for exercise intolerance in patients with CCS.…”

Data Sheet 8_Global, regional, and national burdens of pancreatitis in children and adolescents aged 0–24 years from 1992 to 2021: a trend analysis based on the global burden of di... by Ying-han Deng (21604157)

“…Background<p>The younger onset of pancreatitis presents a significant public health challenge. This study aims to analyze the global burden of pancreatitis in younger populations based on the Global Burden of Disease 2021.…”

Image 4_The global burden of hypertension and its epidemiological impacts on adolescents and young adults: projections to 2050.jpeg by Chaofeng Niu (17746406)

“…</p>Results<p>From 1990 to 2021, the absolute numbers of hypertension-related deaths, Disability-Adjusted Life Years (DALYs), and Years Lived with Disability (YLDs) increased significantly globally. The age-standardized mortality rate and DALY rate decreased to some extent, while the YLDs rate increased slightly. …”

Supplementary Material for: The role of reactive oxygen species in the pathogenesis of alopecia areata: a systematic review and meta-analysis. by Perlmutter J. (11590717)

“…Background: Alopecia areata (AA) is a T-cell-mediated autoimmune disease that significantly impacts patient quality of life. The breakdown of hair follicle immune privilege underlies AA pathogenesis. …”

Image 2_Exercise intolerance in patients with chronic coronary syndrome: insights from exercise stress echocardiography.tiff by Wei-wei Zhu (20349897)

“…An elevated peak EDVi/E/e’ and a decreased ΔSVi are independent risk factors for exercise intolerance in patients with CCS.…”