Table 2_Cardiac energy metabolic disorder and gut microbiota imbalance: a study on the therapeutic potential of Shenfu Injection in rats with heart failure.xlsx حسب Zhenyu Zhao (737165)

"…</p>Results<p>Myocardial energy metabolism in HF rats was disordered, characterized by reduced fatty acid oxidation, enhanced anaerobic glycolysis of glucose, mitochondrial damage, and decreased ATP content; The gut microbiota of HF rats was imbalanced, with a reduction in beneficial bacteria, an increase in conditional pathogenic bacteria, and impaired intestinal barrier function; Both Shenfu Injection and trimetazidine improved myocardial energy metabolism and cardiac function, but Shenfu Injection was more significant in regulating gut microbiota and improving intestinal health; The production of SCFAs from the gut microbiota of HF rats increased, which may be closely related to myocardial energy metabolism; SCFAs-producing bacteria Akkermansia and Blautia played a key role in the development of HF, and their abundance was positively correlated with SCFAs content.…"

Assessment of soil erosion risks and prioritizing nature-based conservation practices using RUSLE, geospatial techniques and household surveys in central Ethiopia حسب Gamachu Yadata Nugusa (22683061)

"…Mann‒Kendall tests (<i>τ</i> = 1.0, <i>p</i> < 0.0001) and Sen's slope confirm significant upward trends in SLR and SY. Sub-catchments 5, 7, and 8 experienced severe erosion; sub-catchments 9, 10, and 12 experienced very high erosion. …"

Table 3_Cardiac energy metabolic disorder and gut microbiota imbalance: a study on the therapeutic potential of Shenfu Injection in rats with heart failure.xlsx حسب Zhenyu Zhao (737165)

"…</p>Results<p>Myocardial energy metabolism in HF rats was disordered, characterized by reduced fatty acid oxidation, enhanced anaerobic glycolysis of glucose, mitochondrial damage, and decreased ATP content; The gut microbiota of HF rats was imbalanced, with a reduction in beneficial bacteria, an increase in conditional pathogenic bacteria, and impaired intestinal barrier function; Both Shenfu Injection and trimetazidine improved myocardial energy metabolism and cardiac function, but Shenfu Injection was more significant in regulating gut microbiota and improving intestinal health; The production of SCFAs from the gut microbiota of HF rats increased, which may be closely related to myocardial energy metabolism; SCFAs-producing bacteria Akkermansia and Blautia played a key role in the development of HF, and their abundance was positively correlated with SCFAs content.…"

Table 1_Cardiac energy metabolic disorder and gut microbiota imbalance: a study on the therapeutic potential of Shenfu Injection in rats with heart failure.xlsx حسب Zhenyu Zhao (737165)

"…</p>Results<p>Myocardial energy metabolism in HF rats was disordered, characterized by reduced fatty acid oxidation, enhanced anaerobic glycolysis of glucose, mitochondrial damage, and decreased ATP content; The gut microbiota of HF rats was imbalanced, with a reduction in beneficial bacteria, an increase in conditional pathogenic bacteria, and impaired intestinal barrier function; Both Shenfu Injection and trimetazidine improved myocardial energy metabolism and cardiac function, but Shenfu Injection was more significant in regulating gut microbiota and improving intestinal health; The production of SCFAs from the gut microbiota of HF rats increased, which may be closely related to myocardial energy metabolism; SCFAs-producing bacteria Akkermansia and Blautia played a key role in the development of HF, and their abundance was positively correlated with SCFAs content.…"

Multi-omics revealed GOT1/ALDH3A1 pathway attenuated head and neck squamous cell carcinoma and increased cisplatin sensitivity through ROS induced by mitochondrial dysfunction حسب Zhihui Liu (95891)

"…Given that mitochondria are the primary source of reactive oxygen species (ROS), we assessed cellular ROS and mitochondrial superoxide levels by flow cytometry and found a significant increase. GOT1 knockdown increased the sensitivity of cells to cisplatin and decreased the volume of tumors in vivo. …"

Table 6_Cardiac energy metabolic disorder and gut microbiota imbalance: a study on the therapeutic potential of Shenfu Injection in rats with heart failure.csv حسب Zhenyu Zhao (737165)

"…</p>Results<p>Myocardial energy metabolism in HF rats was disordered, characterized by reduced fatty acid oxidation, enhanced anaerobic glycolysis of glucose, mitochondrial damage, and decreased ATP content; The gut microbiota of HF rats was imbalanced, with a reduction in beneficial bacteria, an increase in conditional pathogenic bacteria, and impaired intestinal barrier function; Both Shenfu Injection and trimetazidine improved myocardial energy metabolism and cardiac function, but Shenfu Injection was more significant in regulating gut microbiota and improving intestinal health; The production of SCFAs from the gut microbiota of HF rats increased, which may be closely related to myocardial energy metabolism; SCFAs-producing bacteria Akkermansia and Blautia played a key role in the development of HF, and their abundance was positively correlated with SCFAs content.…"

Table 5_Cardiac energy metabolic disorder and gut microbiota imbalance: a study on the therapeutic potential of Shenfu Injection in rats with heart failure.csv حسب Zhenyu Zhao (737165)

"…</p>Results<p>Myocardial energy metabolism in HF rats was disordered, characterized by reduced fatty acid oxidation, enhanced anaerobic glycolysis of glucose, mitochondrial damage, and decreased ATP content; The gut microbiota of HF rats was imbalanced, with a reduction in beneficial bacteria, an increase in conditional pathogenic bacteria, and impaired intestinal barrier function; Both Shenfu Injection and trimetazidine improved myocardial energy metabolism and cardiac function, but Shenfu Injection was more significant in regulating gut microbiota and improving intestinal health; The production of SCFAs from the gut microbiota of HF rats increased, which may be closely related to myocardial energy metabolism; SCFAs-producing bacteria Akkermansia and Blautia played a key role in the development of HF, and their abundance was positively correlated with SCFAs content.…"

Table 8_Cardiac energy metabolic disorder and gut microbiota imbalance: a study on the therapeutic potential of Shenfu Injection in rats with heart failure.csv حسب Zhenyu Zhao (737165)

"…</p>Results<p>Myocardial energy metabolism in HF rats was disordered, characterized by reduced fatty acid oxidation, enhanced anaerobic glycolysis of glucose, mitochondrial damage, and decreased ATP content; The gut microbiota of HF rats was imbalanced, with a reduction in beneficial bacteria, an increase in conditional pathogenic bacteria, and impaired intestinal barrier function; Both Shenfu Injection and trimetazidine improved myocardial energy metabolism and cardiac function, but Shenfu Injection was more significant in regulating gut microbiota and improving intestinal health; The production of SCFAs from the gut microbiota of HF rats increased, which may be closely related to myocardial energy metabolism; SCFAs-producing bacteria Akkermansia and Blautia played a key role in the development of HF, and their abundance was positively correlated with SCFAs content.…"

Table 1_Safety and efficacy of canine recombinant IL-15 in mammary gland tumors.docx حسب Min-Hee Kang (811734)

"…Dogs in the rcIL-15 group showed significantly improved QoL, particularly in pain, appetite, and activity. …"

Data Sheet 1_Decoding population PM2.5 exposure in China: interplay of emissions, meteorology, and inequality (2013–2020).docx حسب Sujing Li (564578)

"…<p>Over the past decade, China has significantly improved air quality by integrating environmental policies with economic growth. …"

Data Sheet 1_Microbial network-driven remediation of saline-alkali soils by salt-tolerant plants.docx حسب Yushuang Cui (2265055)

"…The results indicated that the planting of TC, TA, and HM effectively reduced soil electrical conductivity (EC) by 82.9, 88.3, and 86.2%, respectively. TC and TA significantly decreased the pH from 8.79 to 8.35 and 8.06, respectively, (p < 0.05). …"

Data Sheet 1_From psychological wellbeing to distress: the role of psychological counseling interventions in university students.pdf حسب Francesco Craig (8214780)

"…Post-intervention, psychological distress decreased significantly (p < 0.001), with 56.7% of students falling over the clinical distress cut-off at T1 compared to 84.4% at T0. …"

DataSheet2_Chitinase 1: a novel therapeutic target in metabolic dysfunction-associated steatohepatitis.docx حسب Jung Hoon Cha (19723588)

"…Although the population of F4/80⁺CD11b⁺ intrahepatic mononuclear phagocytes remained unchanged, their infiltration and activation (CHIT1⁺MerTK⁺) significantly decreased in OATD-01-treated mice, compared with that observed in vehicle-treated mice.…"

DataSheet1_Chitinase 1: a novel therapeutic target in metabolic dysfunction-associated steatohepatitis.zip حسب Jung Hoon Cha (19723588)

"…Although the population of F4/80⁺CD11b⁺ intrahepatic mononuclear phagocytes remained unchanged, their infiltration and activation (CHIT1⁺MerTK⁺) significantly decreased in OATD-01-treated mice, compared with that observed in vehicle-treated mice.…"

Data Sheet 1_Age-related trajectories of quality of life in community dwelling older adults: findings from the Survey of Health, Aging and Retirement in Europe (SHARE).docx حسب Sarah Mendorf (11632098)

"…The influence of age was less significant compared to ID and decreased significantly after the addition of covariates.…"

Table 3_Age-related trajectories of quality of life in community dwelling older adults: findings from the Survey of Health, Aging and Retirement in Europe (SHARE).docx حسب Sarah Mendorf (11632098)

"…The influence of age was less significant compared to ID and decreased significantly after the addition of covariates.…"

Table 4_Age-related trajectories of quality of life in community dwelling older adults: findings from the Survey of Health, Aging and Retirement in Europe (SHARE).docx حسب Sarah Mendorf (11632098)

"…The influence of age was less significant compared to ID and decreased significantly after the addition of covariates.…"

Data Sheet 2_Age-related trajectories of quality of life in community dwelling older adults: findings from the Survey of Health, Aging and Retirement in Europe (SHARE).docx حسب Sarah Mendorf (11632098)

"…The influence of age was less significant compared to ID and decreased significantly after the addition of covariates.…"

Table 2_Age-related trajectories of quality of life in community dwelling older adults: findings from the Survey of Health, Aging and Retirement in Europe (SHARE).docx حسب Sarah Mendorf (11632098)

"…The influence of age was less significant compared to ID and decreased significantly after the addition of covariates.…"

Data Sheet 3_Age-related trajectories of quality of life in community dwelling older adults: findings from the Survey of Health, Aging and Retirement in Europe (SHARE).docx حسب Sarah Mendorf (11632098)

"…The influence of age was less significant compared to ID and decreased significantly after the addition of covariates.…"