يعرض 4,541 - 4,560 نتائج من 5,501 نتيجة بحث عن '(( significant decrease decrease ) OR ( significantly improve decrease ))~', وقت الاستعلام: 0.41s تنقيح النتائج
  1. 4541

    Table 1_Bacteroides ovatus-derived N-methylserotonin inhibit colorectal cancer via the HTR1D-mediated cAMP-PKA-NF-κB signaling axis.docx حسب Jikai He (11888466)

    منشور في 2025
    "…</p>Results<p>(1) CRC patients showed significantly increased metabolic pathways including glycolysis, methane metabolism, beneficial amino acid degradation, and linoleic acid degradation, along with significantly decreased B.o abundance and NMS levels, which were positively correlated; (2) NMS significantly inhibited CRC cell proliferation, migration, and invasion, while promoting apoptosis; (3) Combined treatment with B.o and orange fiber or NMS alone reduced tumorigenesis and improved intestinal barrier function; (4) Mechanistic studies revealed that these effects could be mediated through downregulation of 5-hydroxytryptamine receptor 1D (HTR1D) expression and inhibition of the cAMP/PKA/IκBα/NF-κB pathway; (5) The treatments optimized gut microbiota structure and metabolite composition.…"
  2. 4542

    Table 2_Bacteroides ovatus-derived N-methylserotonin inhibit colorectal cancer via the HTR1D-mediated cAMP-PKA-NF-κB signaling axis.xlsx حسب Jikai He (11888466)

    منشور في 2025
    "…</p>Results<p>(1) CRC patients showed significantly increased metabolic pathways including glycolysis, methane metabolism, beneficial amino acid degradation, and linoleic acid degradation, along with significantly decreased B.o abundance and NMS levels, which were positively correlated; (2) NMS significantly inhibited CRC cell proliferation, migration, and invasion, while promoting apoptosis; (3) Combined treatment with B.o and orange fiber or NMS alone reduced tumorigenesis and improved intestinal barrier function; (4) Mechanistic studies revealed that these effects could be mediated through downregulation of 5-hydroxytryptamine receptor 1D (HTR1D) expression and inhibition of the cAMP/PKA/IκBα/NF-κB pathway; (5) The treatments optimized gut microbiota structure and metabolite composition.…"
  3. 4543

    Table 1_Burden of non-CO poisoning in 204 countries and territories, 1990–2021: results from the global burden of disease study 2021.docx حسب Rong Lei (4006232)

    منشور في 2025
    "…Background<p>Non-carbon monoxide (non-CO) poisoning remains a significant global public health issue, contributing to considerable morbidity and mortality. …"
  4. 4544

    Data Sheet 1_Liuweizhiji Gegen-Sangshen beverage protects against alcoholic liver disease in mice through the gut microbiota mediated SCFAs/GPR43/GLP-1 pathway.docx حسب Mingyun Tang (20226342)

    منشور في 2024
    "…LGS significantly improved liver steatosis, enhanced activities of alcohol metabolizing enzymes (ALDH and ADH), and reduced the CYP2E1 activity. …"
  5. 4545

    Table1_Leaf functional traits highlight phenotypic variation of two tree species in the urban environment.xlsx حسب Ahram Cho (20437850)

    منشور في 2024
    "…The urban site had higher daytime and nighttime air, and land surface temperatures compared to the suburban sites with significant fluctuations observed across the sites. …"
  6. 4546

    Datasheet1_Endovascular treatment of aortic coarctation using covered balloon-expandable stents—a systematic review and meta-analysis.pdf حسب Fei He (145896)

    منشور في 2024
    "…The estimated pooled procedural success rate was 100% [95% confidence interval (CI): 98%–100%, I2 = 0, P = 0.78]. Significant decreases in trans-coarctation PGs and SBP were observed. …"
  7. 4547

    Table1_Endovascular treatment of aortic coarctation using covered balloon-expandable stents—a systematic review and meta-analysis.pdf حسب Fei He (145896)

    منشور في 2024
    "…The estimated pooled procedural success rate was 100% [95% confidence interval (CI): 98%–100%, I2 = 0, P = 0.78]. Significant decreases in trans-coarctation PGs and SBP were observed. …"
  8. 4548

    DataSheet1_Leaf functional traits highlight phenotypic variation of two tree species in the urban environment.docx حسب Ahram Cho (20437850)

    منشور في 2024
    "…The urban site had higher daytime and nighttime air, and land surface temperatures compared to the suburban sites with significant fluctuations observed across the sites. …"
  9. 4549

    Analysis of potential targets of 20S-protopanaxadiol on diabetic nephropathy based on network pharmacology, molecular docking, and experimental validation حسب Chenfei Li (5921768)

    منشور في 2025
    "…PPD intragastric administration improved renal function in db/db mice and significantly reduced the expression of TGF-β1, α-SMA, p-Smad3, and Smad4 in renal tissue (<i>p</i> < 0.05). …"
  10. 4550

    Data_Sheet_1_Banxia-Yiyiren alleviates insomnia and anxiety by regulating the gut microbiota and metabolites of PCPA-induced insomnia model rats.zip حسب Liang Wang (23021)

    منشور في 2024
    "…Additionally, there was a significant Pearson correlation between the genus-level differences in the gut microbiota and the differentially abundant metabolites among the G1–G2, G3–G2, and G6–G2 groups.…"
  11. 4551

    Table 1_Efficacy of valgus osteotomy in treating nonunion of femoral neck fractures post-internal fixation.docx حسب Haohao Xu (8909687)

    منشور في 2025
    "…The postoperative follow-up period exceeded one year.</p>Results<p>Significant improvements in biomechanical parameters were observed. …"
  12. 4552

    Supplementary file 1_Dachaihu decoction ameliorates abnormal behavior by regulating gut microbiota in rats with propionic acid-induced autism.docx حسب Yangyang Zhang (608493)

    منشور في 2025
    "…</p>Results<p>DCHD significantly improved autism-like behaviors and increased antioxidant enzyme activity, decreased inflammation and enhanced the intestinal barrier by the animal experiment. …"
  13. 4553

    Data Sheet 1_Dachaihu decoction ameliorates abnormal behavior by regulating gut microbiota in rats with propionic acid-induced autism.zip حسب Yangyang Zhang (608493)

    منشور في 2025
    "…</p>Results<p>DCHD significantly improved autism-like behaviors and increased antioxidant enzyme activity, decreased inflammation and enhanced the intestinal barrier by the animal experiment. …"
  14. 4554

    Table 1_Immediate effects of extracorporeal radial pressure wave therapy on dystonia, static plantar pressure distribution, and balance in patients with Parkinson’s disease.docx حسب Zhiqin Xu (524585)

    منشور في 2025
    "…</p>Results<p>After ERPWT, significant decreases were observed in muscle tone, stiffness, and elasticity of the achilles tendon on the more PD-affected side and the anterior aspect of the planta on both feet (p < 0.05). …"
  15. 4555

    Effects of repeated intravenous esketamine administration on affective biases حسب Christine Reif-Leonhard (20516212)

    منشور في 2025
    "…</p> <p>66.7% participants who received at least five infusions (<i>n</i> = 12) showed significant improvement. Emotion recognition improved for all emotions except sadness, where accuracy decreased, particularly for low-intensity expressions (<i>p</i> = .007, d = −1.09). …"
  16. 4556

    Data Sheet 1_The variation of gut microbiota in captive Sichuan golden snub-nosed monkeys (Rhinopithecus roxellana) from infancy to adulthood.docx حسب Rong Chen (29176)

    منشور في 2025
    "…The relative abundance of Firmicutes positively correlated with increasing age, whereas the abundance of Shigella/Escherichia and Akkermansia was significantly higher in the infants and exhibited a decreasing trend with age. …"
  17. 4557

    Design, synthesis and biological evaluation of non-glucosidal based 1,3,4-thiadiazoles as SGLT-2 inhibitors حسب Shivani Sharma (255210)

    منشور في 2025
    "…SSS 6 and SSS 2 significantly decreased blood glucose levels (137 ± 4.89 mg/dL and 183 ± 15.07 mg/dL) relative to dapagliflozin (158 ± 15.9 mg/dL).…"
  18. 4558

    Image 1_Bright light exposure reduces negative affect and modulates EEG activity in sleep-deprived and well-rested adolescents.tif حسب Jana Kopřivová (14754945)

    منشور في 2025
    "…</p>Results<p>Bright light significantly reduced negative affect and improved Digit Span Forward task performance. …"
  19. 4559

    N-doped TiO<sub>2</sub> with stable surface Ti<sup>3+</sup> for visible light photocatalytic hydrogen production حسب Jieming Chen (386865)

    منشور في 2025
    "…<p>Pure TiO<sub>2</sub> exhibits limited responsiveness to visible light, while the doping of Ti<sup>3+</sup> significantly enhances its absorption efficiency in the visible spectrum, improving the efficiency of photogenerated electron utilization. …"
  20. 4560

    Data Sheet 1_Instructors as communication strategists: using multimodal communication to implement a new course policy on assignment extension due dates.docx حسب Joseph M. Ruesch (18194605)

    منشور في 2025
    "…While the syllabus was the primary source of information, other oral and visual channels were necessary to improve the clarity about the new course policy. Increasing the number of communication channels decreased the confusion about the extension policies. …"