Data Sheet 1_Global burden and trend of stroke attributable to metabolic risks among young adults (20–39 years old) from 1990 to 2021.docx حسب Qingguo Liu (9620123)

"…From 1990 to 2021, the absolute number of stroke-related DALYs attributable to metabolic-risks increased by 22.23%, while the ASDR decreased by 0.78% annually. Regional disparities were evident, with East Asia reporting the largest number of stroke-DALYs attributable to metabolic-risks and Southeast Asia exhibiting the highest ASDR. …"

Table 6_Identification and validation for biomarkers associated with mitochondrial metabolism in chronic obstructive pulmonary disease.xlsx حسب Wenjun Wang (314231)

"…The mRNA and protein expression of APRT and LCAT were significantly decreased in COPD patients’ lung tissues.…"

Evaluation results. حسب Briya Tariq (19666901)

"…It focuses on identifying and quantifying clinically significant materials in the presence of metal objects. …"

Data Sheet 1_Lung microbiome alterations correlate with immune imbalance in non-small cell lung cancer.docx حسب Jiuling Cheng (16890546)

"…Furthermore, patients with higher abundance of Prevotella and Veillonella exhibited a significantly elevated systemic immune-inflammation index (SII) compared to the lower-abundance group (P = 0.0329), while their CD8⁺ T cell levels were significantly decreased in the higher abundance group (P = 0.0027).…"

Data Sheet 1_Based on bioinformatics, SESN2 negatively regulates ferroptosis induced by ischemia reperfusion via the System Xc−/GPX4 pathway.csv حسب Jiejie Hu (6190622)

"…Spearman’s correlation analysis revealed a significant correlation between the hub genes and ferroptosis-related DEGs. …"

Table 1_Associations of urinary enterolignans and risk of overall and cause-specific mortality with or without serum albumin adjustment: a prospective cohort study.docx حسب Zisuo Sun (22310437)

"…Meanwhile, urinary ENL concentrations were associated with decreased all-cause mortality risk (HR = 0.74, 95% CI: 0.59–0.93, P_trend = 0.020) only in the group with higher HSA levels.…"

Table 6_Analyze agricultural efficiency and influencing factors base on the three-stage DEA model and Malmquist index.xlsx حسب Lin-Feng Wang (10944843)

"…TFP peaks at 1.157 (increased by 15.7%) in 2019 and declines to 0.978 (decreased by 2.2%) from 2020 to 2021 due to global economic slowdowns. …"

Data Sheet 1_In silico molecular studies of Phosphinogold(I) thiocarbohydrate complexes: insights into multi-target anticancer mechanisms.docx حسب Alkhair Adam Khalil Mohamed (21529289)

"…While acetylation decreased binding affinity; it enhanced cellular activity as reported in in vitro studies indicative of the need to balance lipophilicity and binding strength in future ligand design.…"

Image 4_Global burden of varicella and herpes zoster across 204 countries, 1990–2021: a temporal trend analysis in the era of the COVID-19 pandemic and projections to 2036.tiff حسب Zilun Wu (18696883)

"…Mortality and DALYs declined significantly, with age-standardized mortality rates (ASMR) and DALYs rates (ASDR) decreasing by 50.0 and 36.3%, respectively. …"

Supplementary Material for: Angiopausin® and Angiopoietin: Unveiling New Mechanisms in Rosacea Treatment through Kinetic Erythema Analysis with the AAREA® Algorithm حسب figshare admin karger (2628495)

"…Reductions in total IEA scores were observed at week 4 (W4; p<0.05) and through W8 to W64 (p<0.001). Decreases in individual scores were also observed for flushing, NTE and edema (W4 to W64: p<0.001), and telangiectasia (W8 to W32; p<0.001). …"

Supplementary file 1_Proof-of-concept of a prior validated LC-MS/MS method for detection of N-lactoyl-phenylalanine in dried blood spots before, during and after a performance diag... حسب H. Bauhaus (22335913)

"…No statistically significant correlations were identified between lac-phe and lactate, glucose as well as anthropometric and respiratory parameters.…"

Table 2_Brown adipocyte exosome - derived C22:6 inhibits the IL-1β signaling pathway to alleviate rheumatoid arthritis.docx حسب Rui Jiang (264894)

"…Introduction<p>Rheumatoid arthritis (RA) is an autoimmune disorder characterized by significant disability and teratogenic effects, for which there are few effective curative therapies. …"

Table 1_Probabilistic human health risk assessment of commercially supplied jar water in Gopalganj municipal area, Bangladesh.docx حسب Partha Pratim Brahma (19696279)

"…<p>Every day, the amount of quality fresh water decreases notably due to contamination of drinking water. …"

Table 4_Antifungal mechanism and transcriptome analysis of Bacillomycin D-C16 against Fusarium oxysporum.xlsx حسب Fuxing Lin (7418234)

"…Furthermore, nearly all DEGs related to DNA replication were significantly suppressed. Biochemical assays confirmed these observations: Reduced activities of mitochondrial enzymes [malate dehydrogenase (MDH), isocitrate dehydrogenase (IDH), pyruvate dehydrogenase (PDH), and complexes I–V], decreased mitochondrial membrane potential, and diminished ATP content collectively indicated mitochondrial dysfunction. …"

Image 2_A unique polygenic mouse model of obesity exhibits a distinct immunological profile that may offer protection against systemic inflammation, diabetes, and behavioral impair... حسب Ulrike Gimsa (9730208)

"…Unlike other mouse lines, DU6 mice do not develop diabetes despite significant obesity. We performed a series of behavioral tests on male mice because obesity is often associated with cognitive and emotional impairment. …"

Table 7_Analyze agricultural efficiency and influencing factors base on the three-stage DEA model and Malmquist index.xlsx حسب Lin-Feng Wang (10944843)

"…TFP peaks at 1.157 (increased by 15.7%) in 2019 and declines to 0.978 (decreased by 2.2%) from 2020 to 2021 due to global economic slowdowns. …"

Impact of COVID-19 on early intervention referrals (Zellner et al., 2025) حسب Matthew A. Zellner (12043395)

"…</p><p dir="ltr"><b>Conclusions: </b>The onset of the pandemic was associated with significant disruption to EI service provision, the magnitude of which varied across states. …"

Figure 3 from Acetalax (Oxyphenisatin Acetate, NSC 59687) and Bisacodyl Cause Oncosis in Triple-Negative Breast Cancer Cell Lines by Poisoning the Ion Exchange Membrane Protein TRP... حسب Makito Mizunuma (18950775)

"…The left shifts of the peaks seen in the sensitive cell lines indicate decreased mitochondrial membrane potential. Carbonyl cyanide-<i>p</i>-trifluoromethoxyphenylhydrazone, an uncoupler of oxidative phosphorylation, was used as the positive control. …"

<b>Mass, Residency Duration, and Previous Experience Shape Post-Escalation but Not Pre-Escalation Outcomes in Experimental Territorial Contests of Atlantic Mudskippers (</b><b><i>P... حسب Michael Smith (21714377)

"…Recent contest experience had significant, role-specific effects only in the post-escalation phase: stronger winner and loser effects in intruders, and a weaker winner effect in residents. …"

Data Sheet 1_EURAD state-of-the-art report: thermo-hydro-mechanical behaviour of clay buffers at high temperatures.pdf حسب María Victoria Villar (20955281)

"…The clay mineralogy was significantly preserved. The slight changes observed in the other properties were opposite depending on the heating conditions: in the case of evaporation, the cation exchange capacity, specific surface area, sorption coefficients, and sometimes swelling pressure decreased. …"