Table 1_Specific drugs for rare diseases in a province of eastern China under catalog management: from 2021 to 2023.docx by Ruifang Nie (8200320)

“…The allocation of 19 drugs increased significantly, and 19 drugs were newly developed. The overall procurement cost of drugs increased and then decreased, which may be related to national policies. …”

Table 1_Efficacy of a novel surgical approach: sutureless correction of conjunctivochalasis using new conjunctival forceps combined with high-frequency electrocautery.docx by Tingting Song (575707)

“…OSDI scores showed no difference between preoperative (38.54) and 1-week postoperative (41.67) values (p=0.922), but significantly decreased by 1 month (16.67, p<0.001). …”

Data Sheet 1_Confronting the anxiety of Generation Z: electroacupuncture therapy regulates oxidative stress and microglia activity in amygdala-basolateral of socially isolated mice... by Tong Yin (3576917)

“…</p>Results<p>Our findings reveal that EA treatment significantly mitigates anxiety-like behaviors in mice, correlating with a reduction in NOX2 expression within BLA microglia and decreased levels of reactive oxygen species (ROS). …”

Table 1_Longitudinal relationships between daily activities, depressive symptoms, anxiety, and suicidality during the COVID-19 pandemic: a three-wave cross-lagged study.docx by Juhee Choi (2619733)

“…Background<p>The COVID-19 pandemic has caused significant unprecedented changes in lives. In particular, core daily activities, such as sleep, diet, physical activity, education, and social activities have significantly changed. …”

Data Sheet 1_Regulated the electrokinetic application of different plant growth stages and parameters enhance the economic extraction of soil heavy metals.docx by Hongyan Ma (109276)

“…</p>Results<p>Results shown that electrokinetic promoted heavy metals accumulation of S. plumbizincicola significantly, and it not show positive correlation absolutely with the application time. …”

Video 1_Efficacy of a novel surgical approach: sutureless correction of conjunctivochalasis using new conjunctival forceps combined with high-frequency electrocautery.mp4 by Tingting Song (575707)

“…OSDI scores showed no difference between preoperative (38.54) and 1-week postoperative (41.67) values (p=0.922), but significantly decreased by 1 month (16.67, p<0.001). …”

DataSheet1_Engineered myeloid precursors differentiate into osteoclasts and resorb heterotopic ossification in mice.docx by Cameron Rementer (20310858)

“…Once symptomatic, HO causes pain, limited mobility and decreased quality of life. Current treatments are limited and have significant complications with high recurrence rates, underscoring the need for improved therapeutic interventions. …”

Data Sheet 1_Acupoint catgut embedding alleviates experimental autoimmune encephalomyelitis by modulating neuroinflammation and potentially inhibiting glia activation through JNK a... by Xiaofang Liu (398453)

“…In ACE-treated mice, EAE disease severity was significantly ameliorated, along with improvements in anxiety-like behaviors and reduced inflammation and demyelination. …”

Table 2_Global, regional and national patterns and gender disparity of intraocular foreign bodies from 1990 to 2021.doc by Yi Shan (160293)

“…The age-standardized DALYs rates of males were significantly higher than those of females in all five SDI groups (p < 0.001) in 2021. …”

Table 1_Short-term influence of Immufen™ on mild allergic rhinitis: a randomized, double-blind, placebo-controlled study.docx by Mamatha K (19843110)

“…</p>Results<p>CQAB supplementation demonstrated a significant (P < 0.05) improvement in Total Nasal Symptom Score (TNSS) compared to placebo and CGM. …”

Data Sheet 1_Ibrutinib enhances the bias of T cell responses towards staphylococcal superantigens sustaining inflammation in chronic lymphocytic leukaemia.pdf by Fisal Tantoush (20936264)

“…<p>Chronic lymphocytic leukaemia (CLL) is an uncurable haematological malignancy and is associated with significant infection morbidity. Bruton’s tyrosine-kinase inhibitors (e.g., ibrutinib) have improved disease outcomes, but severe infections and poor immunization responses afflict patients. …”

Image 1_Immunosuppressants in dermatology on vaccine immunogenicity: a prospective cohort study of pemphigus patients in the pandemic.tif by Kun-Lin Lu (7256960)

“…Intriguingly, we found that daily dosages of 100 mg or more of azathioprine were linked to significantly decreased anti-viral T-cell responses induced by the vaccination (mean of fold change [SD]; higher azathioprine dosage = 0.70 [0.61] folds vs. lower azathioprine dosage = 2.11 [1.03] folds; p = 0.044).…”

Table 1_Global, regional and national patterns and gender disparity of intraocular foreign bodies from 1990 to 2021.doc by Yi Shan (160293)

“…The age-standardized DALYs rates of males were significantly higher than those of females in all five SDI groups (p < 0.001) in 2021. …”

Data Sheet 1_Evaluating the therapeutic potential of BSA-reduced mussel-derived selenium nanoparticles to mitigate copper sulfate-induced hepatic damage and neurodegeneration in a... by Suganiya Umapathy (21383339)

“…Stabilized selenium nanoparticles reduced for 30 minutes (25 μg/ml) showed significant in vitro reactive oxygen species scavenging activity and improved in vivo antioxidant enzyme levels by decreasing lipid peroxidation and nitric oxide levels. …”

Image 2_Immunosuppressants in dermatology on vaccine immunogenicity: a prospective cohort study of pemphigus patients in the pandemic.tif by Kun-Lin Lu (7256960)

“…Intriguingly, we found that daily dosages of 100 mg or more of azathioprine were linked to significantly decreased anti-viral T-cell responses induced by the vaccination (mean of fold change [SD]; higher azathioprine dosage = 0.70 [0.61] folds vs. lower azathioprine dosage = 2.11 [1.03] folds; p = 0.044).…”

Fibroblast growth factor 18 stimulates chondrocyte proliferation by modulating FOXN2 to mitigate post-traumatic osteoarthritis in a mouse model by Gao Xi (22574101)

“…Intra-articular delivery of FGF18 in destabilized medial meniscus (DMM)-induced PTOA mice significantly reduced cartilage erosion and markedly decreased synovial thickening compared to saline-treated controls, with improved cartilage matrix integrity. …”

Supplementary file 1_Colonizable probiotic Lactobacillus paracasei R3 enhances ICI therapy via modulating PBMCs differentiation.docx by Wencan Song (21477434)

“…Our results also showed the rapid adherence of L.p R3 to intestinal epithelial cell membrane, and promoted intestinal epithelial cell expression of mucin mRNA, led to the long maintenance of L.p R3 in colon and cecum in mice. L.p R3 significantly elevated the levels of macrophages, CD4⁺T cells and CD8⁺T cells in PBMCs while simultaneously decreasing the level of programmed cell death protein 1 (PD-1) on the surface of CD4⁺T cells and CD8⁺T cells. …”

Genome-wide association analysis provides insights into the genomics and extracellular expression of <i>Staphylococcus aureus</i> proteases by Shuxian Li (20556455)

“…To identify the genetic variation underlying this variation in protease expression, we employed a <i>k</i>-mer-based genome wide association study, identifying 68 genes with polymorphisms significantly associated with proteolytic activity. Population-scale genomic variation was compared with strains from a sequenced- defined transposon library, validating the function of 27 loci that were significantly associated with decreased protease expression. …”

Supplementary Material for: Effect of Amla extract on Body Mass Index, waist circumference, total body fat, visceral fat, skeletal muscle mass, body age and related parameters: A r... by figshare admin karger (2628495)

“…Additionally, it effectively decreased body age and various anthropometric parameters (e.g., waist circumference, waist-to-hip ratio) significantly (p<0.05), along with reducing BMI, body weight, and improving lipid profile (p<0.05). …”

Supplementary file 1_Therapeutic potential of formononetin in cirrhotic portal hypertension: modulating hepatic fibrosis, macrophage polarization, and lymphangiogenesis.doc by Zhenghao Wu (9732511)

“…For in vitro experiments, hepatic stellate cells, macrophages and lymphatic endothelial cells were used to observe the multiple effects of FN.</p>Results<p>FN significantly ameliorated portal pressure in cirrhosis-induced PHT, improved liver function, and reduced liver fibrosis and hepatic stellate cell activation with decreased SMAD3 protein expression. …”