Outcomes of Corticosteroids Combined with 15 Mg/Week Methotrexate as Initial Treatment for Acute Vogt-Koyanagi-Harada Disease by Yao Lu (185912)

“…All the eyes had retinal reattachment and the choroidal thickness significantly decreased. Sun-set glow fundus was identified in 18 eyes (23.1%). …”

Data Sheet 1_KAE ameliorates LPS-mediated acute lung injury by inhibiting PANoptosis through the intracellular DNA-cGAS-STING axis.zip by Yonghu Chen (2040136)

“…</p>Results<p>KAE significantly alleviated lipopolysaccharide-induced pulmonary injury by reducing inflammatory cell infiltration, alleviating pulmonary edema, enhancing antioxidant capacity, and decreasing levels of inflammatory cytokines in mouse lung tissues. …”

Supplementary file 2_Scorpion-Centipede extracts mitigate ovariectomy-induced osteoporosis in mice through facilitating Cx3cr1 expression.docx by Jinghuai Ni (21023477)

“…</p>Results<p>The results showed that SC treatment significantly improved bone mineral density (BMD), trabecular separation (Tb.Sp), trabecular thickness (Tb.Th), trabecular number (Tb.N), bone volume fraction (BV/TV), and trabecular pattern factor (Tb.Pf) in OVX mice. …”

Supplementary file 1_Restoration of antibiotic associated diarrhea induced gut microbiota disorder by using Dictyophora indusiata water-insoluble polysaccharides in C57BL/6J mice.d... by Yong Lai (4104235)

“…</p>Results<p>Our results showed that DIPY effectively ameliorated AAD in mice by modulating the intestinal flora, increasing microbial diversity, the Shannon and Ace index was significantly higher in the DIPY group than in the NR group after the DIPY intervention (p < 0.001). …”

DataSheet1_Association between amoxicillin administration and outcomes in critically ill patients with acute kidney injury.PDF by Xinyao Luo (12084194)

“…The results indicated significantly lower mortality rates at 30 days (hazard ratio [HR] 0.54, 95% confidence interval [CI] 0.42–0.69) and 90 days (HR 0.64, 95% CI 0.52–0.77) in the amoxicillin group compared to non-recipients. …”

Supplementary file 1_Scorpion-Centipede extracts mitigate ovariectomy-induced osteoporosis in mice through facilitating Cx3cr1 expression.docx by Jinghuai Ni (21023477)

“…</p>Results<p>The results showed that SC treatment significantly improved bone mineral density (BMD), trabecular separation (Tb.Sp), trabecular thickness (Tb.Th), trabecular number (Tb.N), bone volume fraction (BV/TV), and trabecular pattern factor (Tb.Pf) in OVX mice. …”

Data Sheet 1_Exploring the effects of exercise on T cell function and metabolism in cancer: a scoping review protocol.pdf by J. L. Low (22141795)

“…Immunotherapy strategies that leverage the anti-cancer T cell response have significantly advanced therapeutic approaches to cancer treatment. …”

Molecular basis for phenotype observed in <i>Cgulp2</i>Δ and STUbLs in <i>C</i>. <i>glabrata</i>. by Dipika Gupta (204889)

“…Following MG132 treatment, degradation of proteins was prevented and SUMOylated proteins appeared in <i>Cgulp2Δ</i> and <i>Cgulp2ΔCgslx8Δ</i> mutants and so did the improved growth. Based on the experimental validation of quantitative mass spectrometry data, ubiquitin-proteosome pathway, purine nucleotide biosynthesis pathway, and mitochondrial function were found to be significantly impacted in <i>Cgulp2ΔCgslx8Δ</i> double mutant. …”

Data Sheet 1_SNP rs10748643 determines CD39 expression in T and NK cells through altering NFIC binding affinity rather than interfering with RNA splicing.docx by Chenxin Gan (22750214)

“…We found that the amount of each variant is barely affected by SNP mutation in B cells, whereas almost all variants are significantly impacted by SNP mutation in T cells. Such discrepancy in T and B cells does not support the hypothesis that SNP rs10748643 interferes with the splicing efficiency of CD39 mRNA. …”

Supplementary Material for: Global, regional, and national burden of motor neuron disease: a systematic analysis of prevalence, incidence, deaths, and DALYs with projections to 203... by figshare admin karger (2628495)

“…Results: From 1990 to 2021, the global number of MND cases, deaths, and DALYs increased significantly, while the age - standardized prevalence and incidence rates decreased. …”

Image 1_MFN2-a multifaceted guardian against Parkinson’s pathophysiology: mitochondria, ferroptosis, inflammation and oxidative stress.tif by Yan Cheng (149222)

“…</p>Results<p>In PD models, the expressions of DHODH, MFN1, MFN2, GPX4, and FSP1 were significantly down-regulated, and their motor coordination, self-cognitive behavior, and exploration ability were decreased. …”

<b>Increasing ECM tree dominance enhances </b><b>soil </b><b>lignin </b><b>phenols </b><b>but suppresses microbial necromass contribution to soil organic carbon in a subtropical </... by Lu Mengzhen (20146224)

“…Our results indicated that ECM% did not affect SOC content but significantly altered SOC composition. Specifically, a higher ECM% promoted accumulation of plant-derived C and reduced microbial-derived C. …”

Supplementary file 2_Akkermansia muciniphila alleviates cognitive impairment and neuroinflammation induced by blunt chest trauma.docx by Lin Liu (74495)

“…</p>Results<p>Mice subjected to blunt chest trauma displayed emotional abnormalities and cognitive deficits. AKK treatment significantly alleviated anxiety-like behaviors and improved cognitive function, reduced pro-inflammatory cytokine levels in the hippocampus, and reshaped gut microbiota composition. …”

Data Sheet 1_Identification of a multiple DAMP scavenger mimicking the DAMP-binding site of TLR4 to ameliorate lethal sepsis.pdf by Takuya Murao (114383)

“…Additionally, OP18-treated septic mice demonstrated reduced blood organ injury markers, decreased proinflammatory cytokine levels, attenuated ALI, and improved survival. …”

Data Sheet 1_Biological mechanisms of sodium nitroprusside in enhancing quality of Radix Paeoniae Rubra and Radix Paeoniae Alba.docx by Kai Zhao (53042)

“…Due to overwhelming market demand, the cultivated varieties have become the primary source to compensate for insufficient wild resources, which have led to decreased medicinal quality. This study aimed to address this quality decline and put forward a hypothesis that exogenous nitric oxide (NO) induces the reactive oxygen species (ROS)-mediated enhancement of secondary metabolism in fresh roots of P. lactiflora, thereby improving medicinal quality.…”

Data Sheet 1_Intercropping grapevine with Solanum nigrum enhances their cadmium tolerance through changing rhizosphere soil microbial diversity.xlsx by Changbing Pu (14338416)

“…Intercropping with the hyperaccumulator plant Solanum nigrum has emerged as a promising strategy to improve soil health and increase plant resilience to the Cd-contaminated soil.…”

Table1_Inhibition of CISD2 enhances sensitivity to doxorubicin in diffuse large B-cell lymphoma by regulating ferroptosis and ferritinophagy.docx by Chaofeng Zhang (845343)

“…Silencing CISD2 significantly reduced cell proliferation, increased iron accumulation, depleted glutathione (GSH), and elevated malondialdehyde (MDA) levels, alongside the accumulation of ROS and increased MMP. …”

Data_Sheet_1_Guanxin Danshen Formulation Protects against Myocardial Ischemia Reperfusion Injury-Induced Left Ventricular Remodeling by Upregulating Estrogen Receptor β.DOC by Xuehong Deng (13924952)

“…</p><p>Results: We found that +dp/dt and LVSP were significantly elevated in the GXDSF-treated groups compared with the MIRI-LVR model group. …”

Image1_Inhibition of CISD2 enhances sensitivity to doxorubicin in diffuse large B-cell lymphoma by regulating ferroptosis and ferritinophagy.JPEG by Chaofeng Zhang (845343)

“…Silencing CISD2 significantly reduced cell proliferation, increased iron accumulation, depleted glutathione (GSH), and elevated malondialdehyde (MDA) levels, alongside the accumulation of ROS and increased MMP. …”

Image2_Inhibition of CISD2 enhances sensitivity to doxorubicin in diffuse large B-cell lymphoma by regulating ferroptosis and ferritinophagy.JPEG by Chaofeng Zhang (845343)

“…Silencing CISD2 significantly reduced cell proliferation, increased iron accumulation, depleted glutathione (GSH), and elevated malondialdehyde (MDA) levels, alongside the accumulation of ROS and increased MMP. …”