Supplementary data: Assessing healthcare resource utilization burden and unmet treatment needs in patients with Parkinson’s disease: results from a real-world study حسب Malgorzata Ciepielewska (22143499)

"…More effective intervention of patients at intermediate-stage PD may improve symptom control and decrease the PD burden for patients and the healthcare system.…"

The Enzyme Effect: Broadening the Horizon of MS Optimization to Nontryptic Digestion in Proteomics حسب Kinga Nagy (603019)

"…Our results showed a linear <i>m</i>/<i>z</i> dependence for all enzymes, with Glu-C, Asp-N, and chymotrypsin requiring significantly lower energies than trypsin and Arg-C. …"

Data Sheet 1_Therapeutic effects of traditional Chinese medicine Hua-Feng-Dan in a rat model of ischemic stroke involve renormalization of gut microbiota.docx حسب Xiaoxia He (459582)

"…They were also compared in terms of indices of intestinal barrier permeability, inflammation and oxidative stress, brain metabolites as well as composition of the gut microbiota and their metabolites. Hua-Feng-Dan significantly reduced cerebral infarct volume and brain water content and improved neurological score, ischemic brain histopathology, and gut histopathology. …"

DataSheet1_RETRACTED: Ophthalmic Combination of SurR9-C84A and Trichostatin-A Targeting Molecular Pathogenesis of Alkali Burn.DOCX حسب Kislay Roy (3466256)

"…The cytokine array analysis revealed that NaOH induced expressions of IL-1α and MMP-9, which were found to be significantly downregulated (1.8 and 11.5 fold respectively) by the combinatorial treatment of SurR9-C84A and TSA.…"

Table 1_Therapeutic effects of traditional Chinese medicine Hua-Feng-Dan in a rat model of ischemic stroke involve renormalization of gut microbiota.xlsx حسب Xiaoxia He (459582)

"…They were also compared in terms of indices of intestinal barrier permeability, inflammation and oxidative stress, brain metabolites as well as composition of the gut microbiota and their metabolites. Hua-Feng-Dan significantly reduced cerebral infarct volume and brain water content and improved neurological score, ischemic brain histopathology, and gut histopathology. …"

Data Sheet 1_HDL from 36-h fasted participants potently promotes efflux of cholesteryl ester from activated microglia.zip حسب Joanne K. Agus (12889409)

"…HDL from 36-h fasted individuals were significantly more effective in effluxing cholesteryl esters from treated microglia, showing a remarkable 10-fold improvement compared to HDL from the postprandial state. …"

Data Sheet 1_Role of memantine in adult migraine: a systematic review and network meta-analysis to compare memantine with existing migraine preventive medications.docx حسب Guanglu Li (2315128)

"…</p>Conclusion<p>This study provides prioritisation evidence for memantine in migraine prevention, as memantine can significantly decrease the frequency of migraine attacks, improves response rates, and fair acceptability. …"

Table 1_Targeting APE1/Ref-1 to alleviate formalin-induced pain and spinal neuro-inflammation in rats: a promising therapeutic approach.xlsx حسب Eman Elgendy (21811052)

"…Moreover, E3330 administration significantly reduced the expression of key inflammatory mediators including inflammasome markers. …"

Data Sheet 4_Combined treatment with anti-PSMA antibody and human peripheral blood-derived NK cells for castration-resistant prostate cancer.docx حسب Fangming Wang (2810719)

"…CD16 is abundantly expressed in PB-NK cells. The anti-PSMA Ab significantly enhanced the cytotoxicity of NK cells against CRPC cells in vitro, evidenced by increased killing rate, upregulation of the degranulation marker CD107a, increased secretion of interferon-γ, and decreased PSA levels. …"

Data Sheet 1_Effect of levothyroxine on major adverse cardiovascular events in patients with hypothyroidism and cardiovascular disease.docx حسب Lijia Liu (706103)

"…</p>Conclusions<p>Levothyroxine may improve major cardiovascular outcomes and decrease all-cause hospital admissions in patients with hypothyroidism and CVD.…"

Data Sheet 3_Combined treatment with anti-PSMA antibody and human peripheral blood-derived NK cells for castration-resistant prostate cancer.docx حسب Fangming Wang (2810719)

"…CD16 is abundantly expressed in PB-NK cells. The anti-PSMA Ab significantly enhanced the cytotoxicity of NK cells against CRPC cells in vitro, evidenced by increased killing rate, upregulation of the degranulation marker CD107a, increased secretion of interferon-γ, and decreased PSA levels. …"

Data Sheet 2_Combined treatment with anti-PSMA antibody and human peripheral blood-derived NK cells for castration-resistant prostate cancer.docx حسب Fangming Wang (2810719)

"…CD16 is abundantly expressed in PB-NK cells. The anti-PSMA Ab significantly enhanced the cytotoxicity of NK cells against CRPC cells in vitro, evidenced by increased killing rate, upregulation of the degranulation marker CD107a, increased secretion of interferon-γ, and decreased PSA levels. …"

Supplementary file 1_Effects of calcium supplementation on the prevention of preeclampsia: an umbrella review of systematic reviews and meta-analyses.docx حسب Henok Kumsa (8380551)

"…Incorporating calcium supplementation into antenatal care interventions may help to reduce the burden of preeclampsia and improve maternal and fetal outcomes. Further studies are needed to explore the impact of baseline calcium levels, optimal dosage, timing, and routes of supplementation to effectively decrease the incidence of preeclampsia.…"

Data Sheet 1_Combined treatment with anti-PSMA antibody and human peripheral blood-derived NK cells for castration-resistant prostate cancer.xlsx حسب Fangming Wang (2810719)

"…CD16 is abundantly expressed in PB-NK cells. The anti-PSMA Ab significantly enhanced the cytotoxicity of NK cells against CRPC cells in vitro, evidenced by increased killing rate, upregulation of the degranulation marker CD107a, increased secretion of interferon-γ, and decreased PSA levels. …"

Axon Degradation of Dorsal Root Ganglion Cells from Laser Ablation Damage in the Presence of Mdiv Inhibitor حسب Sophia Liu (722004)

"…Results showed that Mdivi-1 treatment significantly reduced cell body degradation, with treated neurons exhibiting a smaller percentage decrease in cell body area compared to untreated controls. …"

Dexmedetomidine pretreatment alleviates brain injury in middle cerebral artery occlusion (MCAO) model rats by activating PI3K/AKT/NF-κB signaling pathway حسب Wei Gao (2085)

"…Neurological function as assessed by the Longa neurological function score test demonstrated significantly reduced neurological scores and increased % infarct size in MCAO group which was blocked by DEX suggesting that DEX might be effective in treating ischemic stroke. …"

research data（Physical and mechanical properties of root reinforced soil-rock mixture based on CT scanning and direct shear methods）.xlsx حسب 家璇 刘 (21578012)

"…The findings indicated a significant correlation between block stone and root shear strength interaction at pressures of 300 kPa to 400 kPa. …"

Data Sheet 1_Aleurone supplementation enhances the metabolic benefits of training in Standardbred mares: impacts on glucose-insulin dynamics and gut microbiome composition.pdf حسب Berit Boshuizen (3747655)

"…</p>Results<p>Training alone: Training significantly improved OGTT parameters by decreasing Maximum_insulin (P = 0.005) and AUC_insulin (P = 0.001), while increasing Time to peak_insulin (P = 0.03), indicating enhanced insulin sensitivity. …"

Image 1_Temporal trends and epidemiological impact of metabolic risk factors on stroke burden in Chinese individuals aged 65 and older, 1992–2021.tif حسب Haiying Wang (6869)

"…High fasting plasma glucose (HFPG), high LDL cholesterol (LDL-C), and high systolic blood pressure (SBP) are significant metabolic risk factors contributing to the increasing stroke burden. …"

Analyzing the effects of integrated care approaches to address co-occurring depression and diabetes: A systematic review and meta-analysis حسب Zach W Cooper (19688646)

"…Of 26 studies reporting HbA1c, IC approaches were associated with a significant between-group difference regarding the percent decrease of HbA1c (d = -0.36, 95% CI: -0.52 to -0.21). …"