Table 3_Impact of chemoradiotherapy for first primary lung cancer on the prognosis and re-chemoradiotherapy sensitivity of second primary lung cancer.docx by Zhe Chen (196097)

“…For SPLC patients with prior FPLC chemoradiotherapy, subsequent SPLC radiotherapy significantly improved prognosis. Notably, this benefit is even more pronounced in patients who have not received prior chemoradiotherapy. …”

Table 1_Impact of chemoradiotherapy for first primary lung cancer on the prognosis and re-chemoradiotherapy sensitivity of second primary lung cancer.docx by Zhe Chen (196097)

“…For SPLC patients with prior FPLC chemoradiotherapy, subsequent SPLC radiotherapy significantly improved prognosis. Notably, this benefit is even more pronounced in patients who have not received prior chemoradiotherapy. …”

TRIM16 mediates secretory autophagy in head and neck cancer-associated fibroblasts by Thuc Ly (12832686)

“…<p>Improving treatment options for head and neck squamous cell carcinoma (HNSCC) requires a deeper understanding of the tumor microenvironment, particularly cancer-associated fibroblasts (CAFs). …”

Effects of liposomal bupivacaine (LB) and provider experience with LB on service utilization, clinical outcomes, and Medicare expenditures among fee-for-service (FFS) beneficiaries by Sarmistha Pal (13348959)

“…Since provider LB use rate can provide better post-surgical outcomes for Medicare patients while reducing overall total Medicare costs, CMS policies could support increased provider LB use by facilitating provider access to LB to have a meaningful impact on reducing opioid consumption and decreasing Medicare expenditures.</p><p></p> <p>Liposomal bupivacaine (LB) represents a significant advancement in postoperative pain management, with studies demonstrating its ability to reduce opioid consumption and improve recovery outcomes. …”

Data Sheet 2_Secreted PD-L1 alleviates inflammatory arthritis in mice through local and systemic AAV gene therapy.docx by Wenjun Li (41954)

“…The levels of pro-inflammatory cytokines in blood were also significantly decreased in shPD-L1 treated mice. Additionally, T cell apoptosis rates in the spleen showed a 2-fold increase in treated mice. …”

Data Sheet 1_Secreted PD-L1 alleviates inflammatory arthritis in mice through local and systemic AAV gene therapy.pdf by Wenjun Li (41954)

“…The levels of pro-inflammatory cytokines in blood were also significantly decreased in shPD-L1 treated mice. Additionally, T cell apoptosis rates in the spleen showed a 2-fold increase in treated mice. …”

Figure 3 from A Cost-Effective Two-Step Approach for Multi-Cancer Early Detection in High-Risk Populations by Shuaipeng Geng (20612220)

“…In the case–control cohort, the two-step MCED approach significantly improved specificity from 91.0% to 99.3%, whereas sensitivity decreased from 49.9% to 39.9%. …”

Data Sheet 1_Hybridization promotes growth performance by altering rumen microbiota and metabolites in sheep.docx by Rui Zhang (13940)

“…Acetate, propionate, and total volatile fatty acid (VFA) concentrations in the DH group were higher than those in the HH group, whereas NH₃-N concentration decreased in the DH and SH groups. Metagenomic analysis revealed that several Prevotella and Fibrobacter species were significantly more abundant in the DH group, contributing to an increased ability to degrade dietary cellulose and enrich their functions in enzymes involved in carbohydrate breakdown. …”

Data Sheet 1_Supplementary far-red light enhances the quality and root development of double-root-cutting grafted watermelon seedlings.docx by Cuinan Wu (650400)

“…Moreover, FR_0.3 light treatment notably decreased reactive oxygen species content and improved antioxidant enzyme activities in roots compared with the control. …”

Table 1_Guiren Runchang granules alleviate slow transit constipation in mice by modulating gut microbiota and short-chain fatty acids.docx by Xinfeng Bai (5049932)

“…The results showed that GRG treatment significantly improved defecation in STC mice and ameliorated intestinal histopathological damage. …”

Knockdown of fatty acid binding protein 3 attenuates cerebral Ischemia-reperfusion injury <i>via</i> inhibiting neuronal apoptosis in mice by Jin-Jin Tian (22046330)

“…FABP3 knockdown markedly reduced infarct volume (20 ± 3.16% <i>vs</i>. 35 ± 2.43% in I/R group, <i>p</i> < 0.001) and improved neurological scores. Histological analysis revealed that FABP3 inhibition significantly attenuated neuronal damage in the penumbra cortex and hippocampal Cornu Ammonis area 1(CA1) region. …”

Table 1_Therapeutic effects of composite probiotics derived from fermented camel milk on metabolic dysregulation and intestinal barrier integrity in type 2 diabetes rats.docx by Tabusi Manaer (10689669)

“…CP levels rose by 21.8% (p < 0.05). Lipid profiles improved: TC decreased by 40.0%, TG by 17.1%, and LDL-C by 30.4% (all p < 0.001). …”

<b>不同辣椒</b><b>chili</b><b>straw on growth performance, rumen fungal flora structure, function and economic benefits of sheep</b> by Jinlong Li (20481890)

“…Key findings include:(1) Dry matter intake (DMI) increased significantly in the 10% CS group (P<0.01), whereas DMI and final body weight decreased in the 20% CS group (P<0.01 or P<0.05); Final body weight and average daily gain (ADG) showed an upward trend in the 10% CS group (P > 0.05), while ADG displayed a downward trend in the 20% CS group (P>0.05); (2) The ACE and Chao1 indices were significantly elevated in the 20% CS group (P<0.05); (3) Principal coordinates analysis (PCoA) and non-metric multidimensional scaling (NMDS) revealed distinct clustering of the 20% CS group compared to the control (CON) group; (4) Relative abundances of Ascomycota and Cladosporium increased, whereas those of Basidiomycota and Kazachstania decreased in CS-supplemented groups (P>0.05); (5) FUNGuild functional prediction indicated that rumen fungi were predominantly symbiotrophic, with increased relative abundances of symbiotrophic and pathotrophic fungi and decreased saprotrophic fungi in CS groups (P>0.05). (6) The gross profit and net profit of CS10 % group increased. …”

Supplementary file 1_Exploration of the renoprotective effect of Yi-Shen-Hua-Shi granules on db/db mice and the mechanism of podocyte apoptosis based on the GRP78/CHOP signaling pa... by Yanmo Cai (22235563)

“…</p>Results<p>YSHS significantly improved the general status of db/db mice, with a significant reduction in body mass, renal function indices, total cholesterol, triglycerides, and low-density lipoprotein. …”

Image 4_Beta-hydroxybutyrate (BHB) elicits concentration-dependent anti-inflammatory effects on microglial cells which are reversible by blocking its monocarboxylate (MCT) importer... by Chase Garcia (21803576)

“…</p>Results<p>At this concentration, BHB significantly and concentration-dependently decreased the following: 1) inflammatory cytokine expression (IL-6, TNF-α, and IL-1β), 2) inflammatory morphological changes, and 3) activation of p-ERK and p-p38MAPK, which are key pathways involved in microglial inflammation. …”

Image 2_Beta-hydroxybutyrate (BHB) elicits concentration-dependent anti-inflammatory effects on microglial cells which are reversible by blocking its monocarboxylate (MCT) importer... by Chase Garcia (21803576)

“…</p>Results<p>At this concentration, BHB significantly and concentration-dependently decreased the following: 1) inflammatory cytokine expression (IL-6, TNF-α, and IL-1β), 2) inflammatory morphological changes, and 3) activation of p-ERK and p-p38MAPK, which are key pathways involved in microglial inflammation. …”

Image 1_Beta-hydroxybutyrate (BHB) elicits concentration-dependent anti-inflammatory effects on microglial cells which are reversible by blocking its monocarboxylate (MCT) importer... by Chase Garcia (21803576)

“…</p>Results<p>At this concentration, BHB significantly and concentration-dependently decreased the following: 1) inflammatory cytokine expression (IL-6, TNF-α, and IL-1β), 2) inflammatory morphological changes, and 3) activation of p-ERK and p-p38MAPK, which are key pathways involved in microglial inflammation. …”

Image 3_Beta-hydroxybutyrate (BHB) elicits concentration-dependent anti-inflammatory effects on microglial cells which are reversible by blocking its monocarboxylate (MCT) importer... by Chase Garcia (21803576)

“…</p>Results<p>At this concentration, BHB significantly and concentration-dependently decreased the following: 1) inflammatory cytokine expression (IL-6, TNF-α, and IL-1β), 2) inflammatory morphological changes, and 3) activation of p-ERK and p-p38MAPK, which are key pathways involved in microglial inflammation. …”

Data_Sheet_1_Compound effects of biochar application and irrigation on soil water and temperature transport.docx by Fuchang Jiang (19966587)

“…<p>The issue of soil salinization poses a significant barrier to sustainable agricultural development, particularly in arid and semi-arid regions. …”

Data Sheet 1_Genetic knockdown of DYRK1A attenuates cognitive impairment, Aβ pathology, tauopathy and neuroinflammatory responses in mouse models of AD.docx by Hyun-ju Lee (7550741)

“…Conversely, in amyloid-beta (Aβ)-overexpressing 5xFAD mice, hippocampal DYRK1A knockdown improved short-term spatial/recognition memory and significantly increased CaMKIIα and CREB phosphorylation. …”