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4721
Data Sheet 1_Aerobic exercise ameliorates atherosclerosis-induced cognitive impairment via hippocampal IL-33/NF-κB signaling modulation.xlsx
Published 2025“…Furthermore, aerobic exercise reduces M1 microglial activation and pro-inflammatory cytokines like IL-6, TNF-α, and IL-1β in the hippocampus of AS mice, thereby decreasing neuroinflammation. In summary, aerobic exercise can effectively improve cognitive function by decreasing IL-33 expression and inhibiting NF-κB activation, which in turn reduces microglial activation and the release of inflammatory mediators in the hippocampus. …”
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4722
Data Sheet 1_Preparation and characteristics of carboxymethyl cellulose-based films embedding cinnamon essential oil and their application on mutton preservation.pdf
Published 2025“…When the CEO increased, the thickness of the films increased, and the moisture absorption and water solubility of the film decreased. Compared with mutton covered without film or with control film, the film containing CEO more significantly reduced pH value, total volatile basic nitrogen, thiobarbituric acid reactive substances, and total bacterial count of mutton samples, improved the color of the meat, and extended the shelf life of the mutton during the 12-day storage at 4°C. …”
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4723
Efficacy and safety of trastuzumab deruxtecan in HER2-high and HER2-low breast cancer: a systematic review and meta-analysis of randomized controlled trials
Published 2025“…A random-effects model revealed that T-DXd significantly improved progression-free survival (hazard ratio [HR] = 0.433; 95% confidence interval [CI]: 0.305–0.616; P < 0.001; <i>I<sup>2</sup></i> = 90.7%) and overall survival (HR = 0.720; 95% CI: 0.636–0.816; P < 0.001; <i>I<sup>2</sup></i> = 0%) versus control regimens, with consistent benefits across HER2 subgroups. …”
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4724
Data Sheet 1_Enhancing spelling competence for English as a foreign language young learners through digital escape rooms.docx
Published 2024“…Mixed methods analyses found that spelling competence in the intervention group as opposed to the control group improved in the post-test and continued to improve significantly in the delayed post-test. …”
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4725
Data Sheet 2_Enhancing spelling competence for English as a foreign language young learners through digital escape rooms.docx
Published 2024“…Mixed methods analyses found that spelling competence in the intervention group as opposed to the control group improved in the post-test and continued to improve significantly in the delayed post-test. …”
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4726
Data Sheet 3_Age-period-cohort analysis of global, regional, and national trends in laryngeal Cancer among older adults, 1990–2021: insights from the 2021 global burden of disease...
Published 2025“…</p>Results<p>From 1990 to 2021, the global ASIR of laryngeal cancer among older adults decreased from 15.16 to 12.25 per 100,000, with significant shifts in trends observed in 1995, 2002, and 2007. …”
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4727
Data Sheet 4_Age-period-cohort analysis of global, regional, and national trends in laryngeal Cancer among older adults, 1990–2021: insights from the 2021 global burden of disease...
Published 2025“…</p>Results<p>From 1990 to 2021, the global ASIR of laryngeal cancer among older adults decreased from 15.16 to 12.25 per 100,000, with significant shifts in trends observed in 1995, 2002, and 2007. …”
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4728
Data Sheet 5_Age-period-cohort analysis of global, regional, and national trends in laryngeal Cancer among older adults, 1990–2021: insights from the 2021 global burden of disease...
Published 2025“…</p>Results<p>From 1990 to 2021, the global ASIR of laryngeal cancer among older adults decreased from 15.16 to 12.25 per 100,000, with significant shifts in trends observed in 1995, 2002, and 2007. …”
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4729
Data Sheet 2_Age-period-cohort analysis of global, regional, and national trends in laryngeal Cancer among older adults, 1990–2021: insights from the 2021 global burden of disease...
Published 2025“…</p>Results<p>From 1990 to 2021, the global ASIR of laryngeal cancer among older adults decreased from 15.16 to 12.25 per 100,000, with significant shifts in trends observed in 1995, 2002, and 2007. …”
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4730
Data Sheet 6_Age-period-cohort analysis of global, regional, and national trends in laryngeal Cancer among older adults, 1990–2021: insights from the 2021 global burden of disease...
Published 2025“…</p>Results<p>From 1990 to 2021, the global ASIR of laryngeal cancer among older adults decreased from 15.16 to 12.25 per 100,000, with significant shifts in trends observed in 1995, 2002, and 2007. …”
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4731
Data Sheet 1_Age-period-cohort analysis of global, regional, and national trends in laryngeal Cancer among older adults, 1990–2021: insights from the 2021 global burden of disease...
Published 2025“…</p>Results<p>From 1990 to 2021, the global ASIR of laryngeal cancer among older adults decreased from 15.16 to 12.25 per 100,000, with significant shifts in trends observed in 1995, 2002, and 2007. …”
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4732
Table 1_Effect of pain-relief nursing on activities of daily living in patients following hip arthroplasty: a systematic review and meta-analysis.docx
Published 2025“…Overall, the pooled effect size was statistically significant, with an indication of overall greater improvement and minimal variability between studies.…”
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4733
Data Sheet 1_Artificial intelligence–enhanced mapping of the international classification of functioning, disability and health via a mobile app: a randomized controlled trial.zip...
Published 2025“…</p>Conclusion<p>The MedQuest mobile application significantly improved workflow efficiency and demonstrated strong concordance between AI- and clinician-assigned ICF mappings. …”
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4734
Data Sheet 1_Nutraceutical supplement slim reshaped colon histomorphology and reduces Mucispirillum schaedleri in obese mice.docx
Published 2025“…</p>Results<p>Our results demonstrated that Slim supplementation significantly improved lipid metabolism, reshaped colon histomorphology, and decreased levels of Mucispirillum schaedleri, which were correlated with VLDL-c and triglycerides.…”
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4735
Data Sheet 1_Global burden, trends and inequalities of maternal hypertensive disorders among reproductive-age women of advanced maternal age, 1990–2021: a population-based study.pd...
Published 2025“…The slope index of inequality (SII) for ASIR improved from −3,052.73 (95% CI: −3,329.55 to −2,775.91) to −1,209.36 (95% CI: −1,393.12 to −1,025.61) per 100,000 women, while the SII for ASDR decreased from −11.29 (95% CI: −12.38 to −10.20) to −3.66 (95% CI: −4.13 to −3.20) deaths per 100,000 women. …”
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4736
Table1_Assessing physical fitness adaptations in collegiate male soccer players through training load parameters: a two-arm randomized study on combined small-sided games and runni...
Published 2024“…</p>Conclusion<p>The 4-week intervention combining SSGs with HIIT did not produce statistically significant improvements in most physical fitness variables compared to the control group. …”
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4737
Image 3_The effect of vitamin K2 supplementation on bone turnover biochemical markers in postmenopausal osteoporosis patients: a systematic review and meta-analysis.tif
Published 2025“…N-telopeptide (NTX) showed no significant change.</p>Conclusions<p>Vitamin K2 supplementation improves key bone turnover biomarkers, particularly OC and ucOC. …”
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4738
Image 1_The effect of vitamin K2 supplementation on bone turnover biochemical markers in postmenopausal osteoporosis patients: a systematic review and meta-analysis.tif
Published 2025“…N-telopeptide (NTX) showed no significant change.</p>Conclusions<p>Vitamin K2 supplementation improves key bone turnover biomarkers, particularly OC and ucOC. …”
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4739
Supplementary Material for: High-sensitivity Troponin I Measurement in a Large Contemporary Cohort: Implications for Clinical Care
Published 2025“…Male sex, higher HDL-C, higher Hgb A1c, decreasing eGFR, and increasing systolic blood pressure were significant predictors of increased hsTnI. …”
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4740
Table 1_Depression score and body mass index mediate the association between dietary vitamin C intake and female infertility: a study based on NHANES 2013–2018.xlsx
Published 2025“…Background<p>The supplement of antioxidants to improve fertility has received widespread attention. …”