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5041
Image 1_Load-bearing aerobic exercise prior to injury moderates systemic immunosuppression response to fracture.jpeg
Published 2025“…Subjects that exercised before fracture had decreased post-fracture circulating immunosuppressive myeloid-derived suppressor cells and pain sensitivity, however there was no significant effect of prehabilitation on bone repair volume, defect bridging rate, or biomechanical properties. …”
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5042
Raw data for quantitative real-time PCR analysis.
Published 2025“…Compared to mice on the P-MAL diet alone, Lp<sup>WJL</sup> supplementation significantly increased muscle mass and size, resulting in enhanced muscle strength and endurance capacity. …”
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5043
DataSheet1_Dipeptide alanine-glutamine ameliorates retinal neurodegeneration in an STZ-induced rat model.docx
Published 2024“…Retinal levels of inflammatory factors were significantly decreased in Ala-Gln-treated diabetic rats. …”
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5044
Image 1_Yacon root is a functional food beneficial for human health: a meta-analysis of clinical trials.pdf
Published 2025“…The pooled results showed that YR significantly reduced BMI [SMD = −0.81, 95%CI (−1.54, −0.08)], decreased stool pH [SMD = −1.12, 95%CI (−1.61, −0.62)], softened stools [SMD = 0.94, 95%CI (0.08, 1.80)], facilitated defecation [SMD = 4.03, 95% CI (0.54, 7.52)], improved fiber consumption patterns [SMD = 0.58, 95%CI (0.18, −0.99)]. …”
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5045
Long-Term Outcomes of Pediatric Pars Planitis: Retrospective Cohort from a Single Tertiary Center in Turkey
Published 2025“…At the final examination, the mean BCVA of the right and left eyes improved significantly (0.08 ± 0.23 and 0.06 ± 0.17, <i>p</i> = 0.006 and <i>p</i> < 0.001, respectively). …”
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5046
Table 1_Angiotensin converting enzyme inhibitors and angiotensin receptor blockers impact on the gut microbiome: a systematic review.docx
Published 2025“…In the human study, ACEi/ARB use did not significantly alter microbial diversity, but decreased populations of facultative aerobic pathogens including Staphylococcus and Enterobacterales. …”
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5047
Table 1_MFN2-a multifaceted guardian against Parkinson’s pathophysiology: mitochondria, ferroptosis, inflammation and oxidative stress.docx
Published 2025“…</p>Results<p>In PD models, the expressions of DHODH, MFN1, MFN2, GPX4, and FSP1 were significantly down-regulated, and their motor coordination, self-cognitive behavior, and exploration ability were decreased. …”
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5048
Supplementary file 1_Synergistic effects of potassium and gibberellin on the yield and quality of yellow pitahaya (Hylocereus megalanthus) fruits in the Peruvian Amazon.docx
Published 2025“…The combination of 100 kg K<sub>2</sub>O ha⁻¹ and 50 mg L⁻¹ GA<sub>3</sub> significantly improved fruit performance, with fruit weight (369.5 g), yield (12 t ha⁻¹), volume (322 cm³), and soluble solids (22.8°Brix), while acidity decreased (pH 4.87 vs. 4.55 in the control). …”
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5049
Image 1_Inhibition SIRT1 to regulate FOXP3 or RORγt can restore the balance of Treg/Th17 axis in ulcerative colitis and enhance the anti-inflammatory effect of moxibustion.pdf
Published 2025“…Finally, in vivo studies, the results have shown that administering EX-527 to inhibit SIRT1 leads to an increasing in FOXP3 expression and a decreasing in RORγt expression in UC colon tissue. In addition, the results indicate that traditional Chinese moxibustion can down regulate the expression of SIRT1, directly affecting the balance of Th17/Treg axis, and the combined use of EX-527 further improves the therapeutic effect of moxibustion.…”
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5050
Table 1_Akkermansia muciniphila alleviates cognitive impairment and neuroinflammation induced by blunt chest trauma.docx
Published 2025“…</p>Results<p>Mice subjected to blunt chest trauma displayed emotional abnormalities and cognitive deficits. AKK treatment significantly alleviated anxiety-like behaviors and improved cognitive function, reduced pro-inflammatory cytokine levels in the hippocampus, and reshaped gut microbiota composition. …”
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5051
Raw data for body and muscle weights.
Published 2025“…Compared to mice on the P-MAL diet alone, Lp<sup>WJL</sup> supplementation significantly increased muscle mass and size, resulting in enhanced muscle strength and endurance capacity. …”
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5052
Raw data for micro-CT analysis of the femur.
Published 2025“…Compared to mice on the P-MAL diet alone, Lp<sup>WJL</sup> supplementation significantly increased muscle mass and size, resulting in enhanced muscle strength and endurance capacity. …”
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5053
Table 1_Weight loss increases circadian gene expression and emotional well-being in individuals with obesity.docx
Published 2025“…Self-esteem did not significantly increase; however, the proportion of participants with high self-esteem rose from 62 to 69% (χ<sup>2</sup> = 12.5, p < 0.05). …”
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5054
Data Sheet 2_KAE ameliorates LPS-mediated acute lung injury by inhibiting PANoptosis through the intracellular DNA-cGAS-STING axis.pdf
Published 2025“…</p>Results<p>KAE significantly alleviated lipopolysaccharide-induced pulmonary injury by reducing inflammatory cell infiltration, alleviating pulmonary edema, enhancing antioxidant capacity, and decreasing levels of inflammatory cytokines in mouse lung tissues. …”
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5055
In vivo antitumor activity of PHT-427 inhibitor-loaded polymeric nanoparticles in head and neck squamous cell carcinoma
Published 2025“…PHT-427 encapsulation increased drug efficacy and safety, as demonstrated by decreased tumor volume, reduced PI3K/AKT/PDK1 pathway expression, and improved antitumor activity and necrosis induction in the mouse xenograft model. …”
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5056
Data Sheet 1_Exploring long COVID in pediatric patients: clinical insights from a long COVID clinic.docx
Published 2025“…Overall symptom burden decreased significantly over time (p < 0.001). Vaccination status at baseline was not associated with difference in symptom duration on initial presentation (p = 0.4). …”
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5057
Image 4_Inhibition SIRT1 to regulate FOXP3 or RORγt can restore the balance of Treg/Th17 axis in ulcerative colitis and enhance the anti-inflammatory effect of moxibustion.tif
Published 2025“…Finally, in vivo studies, the results have shown that administering EX-527 to inhibit SIRT1 leads to an increasing in FOXP3 expression and a decreasing in RORγt expression in UC colon tissue. In addition, the results indicate that traditional Chinese moxibustion can down regulate the expression of SIRT1, directly affecting the balance of Th17/Treg axis, and the combined use of EX-527 further improves the therapeutic effect of moxibustion.…”
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5058
Unpowered dust removal system field physical map.
Published 2025“…Field tests confirmed that after implementing the improved dust removal system, the ambient air dust concentration decreased to less than 2 mg/m³, representing a reduction of approximately 92.02% compared to pre-transformation levels. …”
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5059
Real-time PCR primer sequences.
Published 2025“…Compared to mice on the P-MAL diet alone, Lp<sup>WJL</sup> supplementation significantly increased muscle mass and size, resulting in enhanced muscle strength and endurance capacity. …”
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5060
Image 2_Inhibition SIRT1 to regulate FOXP3 or RORγt can restore the balance of Treg/Th17 axis in ulcerative colitis and enhance the anti-inflammatory effect of moxibustion.tif
Published 2025“…Finally, in vivo studies, the results have shown that administering EX-527 to inhibit SIRT1 leads to an increasing in FOXP3 expression and a decreasing in RORγt expression in UC colon tissue. In addition, the results indicate that traditional Chinese moxibustion can down regulate the expression of SIRT1, directly affecting the balance of Th17/Treg axis, and the combined use of EX-527 further improves the therapeutic effect of moxibustion.…”