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significantly increase » significantly increased (Expand Search), significant increase (Expand Search), significantly decreased (Expand Search)
significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
increase decrease » increased release (Expand Search), increased crash (Expand Search)
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17721
“Engineering Rifampicin-Encapsulated Inhalable Microparticles for Precision Tuberculosis Therapy: In Vivo Distribution and Therapeutic Evaluation”
Published 2025“…The TB-infected mice, which showed the lung tissue bacterial load was reduced to 3.2 log colony forming unit (CFU) and the levels of TNF-α were decreased while IL-10 levels were increased. With this kind of accelerated stability testing it was ascertained that the type of formulation had a shelf-life of 24 months.…”
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17722
Supplemental Material for Dhiman et al., 2025
Published 2025“…Beyond reduced amylose content, <em>wxe</em> exhibited increased kernel hardness, elevated protein content, reduced endosperm-to-germ ratio, and decreased kernel weight compared to the wild-type. …”
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17723
Height and canopy measurements of native shrubs in southern California
Published 2025“…We identified four key findings: (1) shrub biomass increased with time since last fire and the proportion of resprouting species, and decreased with distance to coast and solar radiation; (2) species with the ability to resprout (obligate resprouter and facultative seeders) contributed greater biomass at all post-fire time periods and locations when compared with obligate seeders; (3) we found higher average biomass contributed by both obligate seeder and obligate resprouter species in plots closer to the coast than interior plots; and (4) fourth, we found a significant positive relationship between woody shrub richness and biomass. …”
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17724
Supplementary Material for: Thyroid hormone clearance in the paraventricular nucleus of male mice regulates lean mass and physical activity
Published 2024“…However, inactivation of Dio3 in the PVN resulted in increased body weight (both fat mass and lean mass) and locomotor activity, and decreased hypothalamic Mc4r expression in male, but not female mice. …”
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17725
Data Sheet 1_Vagal nerve signals are modulated by spontaneous seizures in Genetic Absence Epilepsy Rats from Strasbourg.docx
Published 2025“…However, this modulation decreased with age, despite stable seizure severity. …”
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17726
Table 1_CyTOF reveals platelet subtype changes predicting the efficacy of combined immunotherapy and targeted therapy in liver cancer.docx
Published 2025“…Notably, this subpopulation decreased with tumor remission and increased with tumor progression.…”
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17727
Effects of eucalypt and black wattle biochars from vacuum pyrolysis on sandy soil quality and cauliflower yield
Published 2025“…<p>Woody invasive alien plants (IAPs), including black wattle (<i>Acacia mearnsii</i> De Wild.) and eucalypt species (<i>Eucalyptus camaldulensis</i> Dehnh.), present significant environmental challenges in South Africa. …”
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17728
Table 1_Multi-omics revealed that the postbiotic of hawthorn-probiotic alleviated constipation caused by loperamide in elderly mice.pdf
Published 2025“…Network pharmacology identified 20 cross-targets of FS in constipation. RT-qPCR showed decreased NR1I2 and SULT1A1 and increased GLP-2r in FS-treated mice. …”
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17729
Loss of b-cell K<sub>ATP</sub> reduces Ca<sup>2+</sup> sensitivity of insulin secretion and <i>Trpm5</i> expression
Published 2024“…</a><a href="" target="_blank">Glibenclamide pellet-implanted <i>Trpm5</i> KO mice also exhibited significant glucose intolerance. However, this was not as severe as in WT animals, which suggests that decreased expression of <i>Trpm5</i> may play a small role in the disruption of insulin secretion with K<sub>ATP</sub> loss.…”
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17730
The global disability-adjusted life years (DALYs) for asthma attributable to nitrogen dioxide pollution from 1990 to 2021 and predicted the trends from 2022 to 2050
Published 2025“…The global trend in ASDALYs is projected to decline until 2029, reaching approximately 2.96, before increasing to 7.12 by 2050.</p> <p>From 1990 to 2021, the global DALYs for asthma attributed to NO<sub>2</sub> pollution have generally decreased. …”
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17731
Data Sheet 1_Immunotherapy for neuromyelitis optica spectrum disorder: a comparative analysis of efficacy and safety of azathioprine, mycophenolate mofetil, tacrolimus, and rituxim...
Published 2025“…The annual relapse rate (ARR) significantly decreased after treatment with all four drugs. …”
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17732
The quality metrics of 4C-seq data.
Published 2025“…Functional assays demonstrated that targeted repression of Pparα-En4 region significantly decreased <i><i>Ppar</i>α</i> expression and impaired brown adipocyte differentiation and thermogenesis. …”
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17733
Table 1_From feed to field: effect of dietary protein level and use of a blend of feed additives on gaseous emissions from growing-finishing pig slurry.docx
Published 2025“…NH<sub>3</sub> emissions from the room and slurry pit decreased by over 38%, while CH<sub>4</sub> emissions, although higher in LP diets, were mitigated with the LPA diet. …”
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17734
Raw data for quantitative real-time PCR analysis.
Published 2025“…Compared to mice on the P-MAL diet alone, Lp<sup>WJL</sup> supplementation significantly increased muscle mass and size, resulting in enhanced muscle strength and endurance capacity. …”
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17735
Data Sheet 1_Autoimmune thyroid disease and human health: a systematic review of Mendelian randomization studies.xlsx
Published 2025“…MR analyses indicated that AITD significantly increased the risk of coronary atherosclerosis, deep venous thrombosis, chronic obstructive pulmonary disease, major depression, diabetic neuropathy, carpal tunnel syndrome, neuromyelitis optica spectrum disorder, diabetic retinopathy, childhood absence epilepsy, rheumatoid arthritis, systemic lupus erythematosus, psoriatic arthritis, inflammatory bowel disease, crohn's disease, vitiligo, myasthenia gravis, alopecia areata, type 1 and type 2 diabetes, sarcoidosis, frozen shoulder, drug eruptions, cataract, early age-related macular degeneration, pernicious anemia, Helicobacter pylori infection, temporomandibular disorders, migraine, frailty, primary biliary cholangitis, knee osteoarthritis, gout, and osteoporosis, while decreasing the risk of lung cancer, polyneuropathies, allergic rhinitis, telomere length, and serum vitamin A levels. …”
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17736
Tilmicosin inhibits the infections of currently prevalent porcine reproductive and respiratory syndrome viruses via the downregulation of CD163 expression
Published 2025“…Flow cytometric analysis indicated that anti-inflammatory may reverse the downregulation effect of tilmicosin on CD163, while pro-inflammatory mediators can enhance the downregulation effect of tilmicosin on CD163, which leads to increased and decreased replication of PRRSV, respectively. …”
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17737
Image 2_Viral encephalitis and seizures cause rapid depletion of neuronal progenitor cells and alter neurogenesis in the adult mouse dentate gyrus.tif
Published 2025“…They resumed proliferation at 14 dpi, but, did not recover to CTR levels, and displayed aberrant migration patterns. (2) The number of proliferating NSCs significantly decreased within the dorsal DG of TMEV mice at 14 dpi compared to CTR, while (3) a heightened population of proliferating astrocytes was observed. …”
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17738
Data Sheet 1_Chito-oligosaccharide composites enhanced the adaptability of cotton seedlings to salinized soil by modulating photosynthetic efficiency and metabolite.doc
Published 2025“…The results showed that salt stress reduced the contents of K<sup>+</sup> and Ca<sup>2+</sup> and enhanced the content of Na<sup>+</sup> in cotton leaves compared to the control, which inhibited leaf photosynthesis and seedling growth. COS-PA application decreased leaf Na<sup>+</sup> content significantly in salt-stressed cotton seedlings by 69.70%, and increased the leaf Ca<sup>2+</sup> content, fresh weight of each plant part, transpiration rate, leaf chlorophyll concentration (Chl a), actual quantum yield, as well as stomatal conductance by 7.22%, 46.33%-96.36%, 96.65%, 44.53%, 27.15%, and 168.24%, respectively, compared with the no COS-PA application treatment. …”
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17739
Image 9_Isolation and identification of Alternaria alstroemeriae causing postharvest black rot in citrus and its control using curcumin-loaded nanoliposomes.jpeg
Published 2025“…Curcumin-loaded nanoliposomes also enhanced the activities of the enzymes PPO, APX, POD, PAL, GR and CAT of citrus, decreased the O<sub>2</sub><sup>−</sup> production rate. …”
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17740
Table 1_Speckle tracking technology and investigation of risk factors for premature ventricular contraction-induced cardiomyopathy.pdf
Published 2025“…Regression analysis revealed that asymptomatic PVCs, paired/interpolated PVCs, wide QRS duration (≥150 ms), and higher PVC burden were significantly associated with decreased GLS and GCS magnitude. …”