Supplementary Material for: The current status of tumor markers as biomarkers in the era of immunotherapy for hepatocellular carcinoma: alpha-fetoprotein alone is not sufficient by Hiraoka A. (4273894)

“…Positive rates for AFP (67.8%, 62.1%, 50.8%, respectively) and DCP (84.1%, 80.5%, 72.7%, respectively) were decreased (each P<0.001), while the AFP-L3 rate did not show a significant change (54.4%, 57.7%, 51.9%, respectively P=0.390). …”

Supplementary file 2_Development and preliminary clinical feasibility of a Delphi-based aerobic exercise prescription for children with asthma.docx by Ying Zhang (40767)

“…Post-intervention outcomes showed significant improvements: 6MWD increased from 510.07 ± 31.96 to 539.27 ± 44.52 m (P < 0.001); forced expiratory volume in 1 s (FEV1)% predicted increased from 76.87 ± 5.63 to 87.61 ± 7.24 (P < 0.001); and C-ACT score increased from 17.60 ± 1.76 to 22.13 ± 1.46 (P < 0.001).…”

Supplementary file 6_Development and preliminary clinical feasibility of a Delphi-based aerobic exercise prescription for children with asthma.docx by Ying Zhang (40767)

“…Post-intervention outcomes showed significant improvements: 6MWD increased from 510.07 ± 31.96 to 539.27 ± 44.52 m (P < 0.001); forced expiratory volume in 1 s (FEV1)% predicted increased from 76.87 ± 5.63 to 87.61 ± 7.24 (P < 0.001); and C-ACT score increased from 17.60 ± 1.76 to 22.13 ± 1.46 (P < 0.001).…”

Supplementary file 1_Development and preliminary clinical feasibility of a Delphi-based aerobic exercise prescription for children with asthma.docx by Ying Zhang (40767)

“…Post-intervention outcomes showed significant improvements: 6MWD increased from 510.07 ± 31.96 to 539.27 ± 44.52 m (P < 0.001); forced expiratory volume in 1 s (FEV1)% predicted increased from 76.87 ± 5.63 to 87.61 ± 7.24 (P < 0.001); and C-ACT score increased from 17.60 ± 1.76 to 22.13 ± 1.46 (P < 0.001).…”

Supplementary file 5_Development and preliminary clinical feasibility of a Delphi-based aerobic exercise prescription for children with asthma.docx by Ying Zhang (40767)

“…Post-intervention outcomes showed significant improvements: 6MWD increased from 510.07 ± 31.96 to 539.27 ± 44.52 m (P < 0.001); forced expiratory volume in 1 s (FEV1)% predicted increased from 76.87 ± 5.63 to 87.61 ± 7.24 (P < 0.001); and C-ACT score increased from 17.60 ± 1.76 to 22.13 ± 1.46 (P < 0.001).…”

Supplementary file 4_Development and preliminary clinical feasibility of a Delphi-based aerobic exercise prescription for children with asthma.docx by Ying Zhang (40767)

“…Post-intervention outcomes showed significant improvements: 6MWD increased from 510.07 ± 31.96 to 539.27 ± 44.52 m (P < 0.001); forced expiratory volume in 1 s (FEV1)% predicted increased from 76.87 ± 5.63 to 87.61 ± 7.24 (P < 0.001); and C-ACT score increased from 17.60 ± 1.76 to 22.13 ± 1.46 (P < 0.001).…”

Image 1_Dysfunctional β-cell autophagy induces β-cell stress and enhances islet immunogenicity.tiff by Matthew C. Austin (20633168)

“…Gene ontology analysis revealed a significant upregulation of pathways involved in inflammatory processes, response to ER stress, and the ER-associated degradation pathway. …”

Image 3_Dysfunctional β-cell autophagy induces β-cell stress and enhances islet immunogenicity.tiff by Matthew C. Austin (20633168)

“…Gene ontology analysis revealed a significant upregulation of pathways involved in inflammatory processes, response to ER stress, and the ER-associated degradation pathway. …”

Image 4_Dysfunctional β-cell autophagy induces β-cell stress and enhances islet immunogenicity.tif by Matthew C. Austin (20633168)

“…Gene ontology analysis revealed a significant upregulation of pathways involved in inflammatory processes, response to ER stress, and the ER-associated degradation pathway. …”

Image 2_Dysfunctional β-cell autophagy induces β-cell stress and enhances islet immunogenicity.tiff by Matthew C. Austin (20633168)

“…Gene ontology analysis revealed a significant upregulation of pathways involved in inflammatory processes, response to ER stress, and the ER-associated degradation pathway. …”

Table 1_Optimal fertilizer rate and sowing density can improve oat quality, yield and N and P comprehensive efficiency in the Loess Plateau of China.docx by Ruochen Zhang (3434996)

“…In the M treatment, the average crude protein (CP) content, relative feed value (RFV), forage yield, CP yield, N content, P content, N uptake and P uptake increased by 20.2%, 4.9%, 73.2%, 100%, 30.4%, 26.3%, 128.5% and 118.4%, respectively, compared with those under the no fertilization treatment; while the average neutral detergent fiber (NDF) decreased by 2.6% in the N1P2 treatment compared to no fertilization treatment. …”

Extraction time and mustard concentration for extraction of aquatic oligochaetes by using wet funnel by Satoshi Kaneda (571209)

“…Extraction efficiency in Exp. S1.1 increased with extraction time, reaching over 80% at 1.5 h, after which the rate of increase slowed. …”

DataSheet_1_Maternal and neonatal immune response to SARS-CoV-2, IgG transplacental transfer and cytokine profile.docx by Rocío Rubio (513839)

“…Those with symptoms had higher cytokine levels. IFN-α was increased in cord blood from infected mothers, and in cord blood of symptomatic mothers, EGF, FGF, IL-17 and IL-15 were increased, whereas RANTES was decreased. …”

Data Sheet 1_Prevalence trends, population characteristics and treatment outcomes of tuberculosis combined with diabetes in Southwest China: a register-based retrospective study.do... by Deliang Kong (382201)

“…</p>Results<p>From 2016 to 2022, the incidence rate of PTB in southwest China showed a decreasing trend (AAPC = -10.22, 95% CI: −11.49% ~ −8.94%), while the incidence rate of PTB-DM increased rapidly (AAPC = 14.25, 95% CI: 11.35% ~17.23%). …”

Image 2_Standardized aqueous extract of Abutilon theophrasti Medic. ameliorates oxidative stress and inflammatory responses against hydrochloric acid/ethanol-induced gastric ulcer... by Hui Guo (110581)

“…In vivo, ATAE markedly attenuated the HCl-/EtOH-induced GU and mucosal injuries; decreased the levels of pro-inflammatory/oxidant mediators, including TNF-α, IL-1β, IL-6, and malondialdehyde (MDA); increased the anti-oxidant activity of mediators superoxide dismutase (SOD) and glutathione peroxidase (GSH-Px); and inhibited the phosphorylation/activation of Akt, IκBα, and NF-κB p65 in gastric tissues. …”

Image 1_Standardized aqueous extract of Abutilon theophrasti Medic. ameliorates oxidative stress and inflammatory responses against hydrochloric acid/ethanol-induced gastric ulcer... by Hui Guo (110581)

“…In vivo, ATAE markedly attenuated the HCl-/EtOH-induced GU and mucosal injuries; decreased the levels of pro-inflammatory/oxidant mediators, including TNF-α, IL-1β, IL-6, and malondialdehyde (MDA); increased the anti-oxidant activity of mediators superoxide dismutase (SOD) and glutathione peroxidase (GSH-Px); and inhibited the phosphorylation/activation of Akt, IκBα, and NF-κB p65 in gastric tissues. …”

Data Sheet 1_Efficacy and safety of Tongxinluo capsules combined with conventional therapy for acute myocardial infarction: a systematic review and meta-analysis.zip by Dan Ouyang (554436)

“…The meta-analysis revealed that Tongxinluo capsule combined with conventional treatment significantly decreased the 1-month MACCE rate (RR = 0.62, 95% CI 0.47 to 0.81; p = 0.0007), along with the individual risks of 1-month MACCE, including cardiac death (RR = 0.68, 95% CI 0.50 to 0.93; p = 0.02) and myocardial reinfarction (RR = 0.11, 95% CI 0.01 to 0.94; p = 0.04). …”

Data Sheet 2_Efficacy and safety of Tongxinluo capsules combined with conventional therapy for acute myocardial infarction: a systematic review and meta-analysis.zip by Dan Ouyang (554436)

“…The meta-analysis revealed that Tongxinluo capsule combined with conventional treatment significantly decreased the 1-month MACCE rate (RR = 0.62, 95% CI 0.47 to 0.81; p = 0.0007), along with the individual risks of 1-month MACCE, including cardiac death (RR = 0.68, 95% CI 0.50 to 0.93; p = 0.02) and myocardial reinfarction (RR = 0.11, 95% CI 0.01 to 0.94; p = 0.04). …”

Revisiting the association between sodium-glucose cotransporter-2 inhibitors and the risk of neoplasm in patients with type 2 diabetes: new insights from an updated systematic revi... by Yiran Wang (1492303)

“…However, decreased risk of pulmonary neoplasm (RR = 0.83, 95% CI: 0.69 to 0.99, I² = 0.0%) was observed in SGLT-2i users compared to non-users, while increased risk of prostate neoplasm in SGLT-2i users was found (RR = 1.21, 95% CI: 1.00 to 1.47, I² = 0.0%).…”

Protein and gene expression levels of p62 and LC3B in miR-7974 mimic-transfected MCF-7 cells. by Stralina Eneh (21213312)

“…<b>(B)</b> The fold change of p62 and <b>(C)</b> LC3BI between negative control/cell-only samples and miR-7974-treated samples were statistically significant. GAPDH was used as a reference protein. …”