Search alternatives:
significantly increases » significantly increased (Expand Search), significantly increase (Expand Search), significant increases (Expand Search)
significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
increases decrease » increased release (Expand Search)
significantly increases » significantly increased (Expand Search), significantly increase (Expand Search), significant increases (Expand Search)
significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
increases decrease » increased release (Expand Search)
-
19901
Data Sheet 1_Safety profile and efficacy of secukinumab in the treatment of autoimmune myasthenia gravis: a single-center retrospective study.pdf
Published 2025“…</p>Results<p>By week 24, secukinumab treatment led to significant reductions in disease severity scores (QMG: 60.7%; MG-QOL15: 58.3%; MG-ADL: 64.1%) and AChR antibody levels (69.23%). …”
-
19902
Image 4_Changes in symptom pattern in Meniere's disease by duration: the need for comprehensive management.tif
Published 2024“…The frequency and duration of vertigo attacks generally decreased over time, with attacks becoming shorter and less severe as the disease progressed. …”
-
19903
Table1_Predicting candidate miRNAs for targeting begomovirus to induce sequence-specific gene silencing in chilli plants.docx
Published 2024“…Chilli cultivars infected with begomovirus have suffered significant decreases in biomass output, negatively impacting their economic characteristics. …”
-
19904
Image 2_A zebrafish model of crim1 loss of function has small and misshapen lenses with dysregulated clic4 and fgf1b expression.tiff
Published 2025“…Crim1 encodes a type I transmembrane protein that is expressed at the cell membrane of lens epithelial and fiber cells at the stage of lens pit formation. Decreased Crim1 expression in the mouse reduced the number of lens epithelial cells and caused defective adhesion between lens epithelial cells and between the epithelial and fiber cells.…”
-
19905
Image 5_Changes in symptom pattern in Meniere's disease by duration: the need for comprehensive management.tif
Published 2024“…The frequency and duration of vertigo attacks generally decreased over time, with attacks becoming shorter and less severe as the disease progressed. …”
-
19906
Data Sheet 1_Breaking the cancer code: a novel DNA minicircle to disable STAT3 in ovarian cancer cells SKOV3.docx
Published 2025“…Mechanistically, anti-STAT3 mcDNA induces apoptosis and necrosis in treated cells, also revealing a certain dose-dependency, while also decreasing cell proliferation. Finally, our inhibitor significantly downregulates STAT3-dependent anti-apoptotic genes MCL1 and PIM1.…”
-
19907
Table 5_A zebrafish model of crim1 loss of function has small and misshapen lenses with dysregulated clic4 and fgf1b expression.docx
Published 2025“…Crim1 encodes a type I transmembrane protein that is expressed at the cell membrane of lens epithelial and fiber cells at the stage of lens pit formation. Decreased Crim1 expression in the mouse reduced the number of lens epithelial cells and caused defective adhesion between lens epithelial cells and between the epithelial and fiber cells.…”
-
19908
Study of monopolar plate springback applying zoned multistage forming process
Published 2025“…The length and width of an MPP both exceed 150 mm, but the thickness of its raw material plate is less than 0.1 mm, posing a significant challenge to the uniformity of its thickness after forming. …”
-
19909
Table 1_Dihydromyricetin attenuates age-related macular degeneration: pharmacological effects and exploration of putative targets.docx
Published 2025“…Western blot analysis further confirmed DHM-mediated suppression of apoptosis through regulation of p53, Bax, cleaved caspase-3, and Bcl-2 expression. High-dose DHM significantly attenuated retinal thinning (10.7% reduction), decreased pigment loss, and ameliorated structural disorganization in the outer nuclear layer (ONL). …”
-
19910
Image2_Predicting candidate miRNAs for targeting begomovirus to induce sequence-specific gene silencing in chilli plants.jpeg
Published 2024“…Chilli cultivars infected with begomovirus have suffered significant decreases in biomass output, negatively impacting their economic characteristics. …”
-
19911
Data Sheet 1_Effects and safety of Salvia miltiorrhiza on the improvement of renal function, inflammatory factors, and vascular endothelium in patients with diabetic kidney disease...
Published 2025“…Notably, the safety profile remained sound, with no significant differences in adverse event rates between the two groups (P > 0.05).…”
-
19912
Image 4_A zebrafish model of crim1 loss of function has small and misshapen lenses with dysregulated clic4 and fgf1b expression.tiff
Published 2025“…Crim1 encodes a type I transmembrane protein that is expressed at the cell membrane of lens epithelial and fiber cells at the stage of lens pit formation. Decreased Crim1 expression in the mouse reduced the number of lens epithelial cells and caused defective adhesion between lens epithelial cells and between the epithelial and fiber cells.…”
-
19913
Supplementary Material for: The value of circulating tumor DNA in the prognostic diagnosis of bladder cancer: a systematic review and meta-analysis
Published 2025“…Deeks funnel plot analysis showed no significant publication bias (P=0.24). However, inter-study heterogeneity was high (all I² values >80%), which may have been influenced by factors such as assay technique, patient characteristics, and follow-up time. …”
-
19914
DataSheet1_Neuroprotective effect of Bouvardia ternifolia (Cav.) Schltdl via inhibition of TLR4/NF-κB, caspase-3/Bax/Bcl-2 pathways in ischemia/reperfusion injury in rats.PDF
Published 2024“…This lowers oxidative stress and decreases the expression of proteins and genes linked to cell death, such as Bax, Bcl-2, and caspase-3. …”
-
19915
Image 3_The effects of antioxidant supplementation on pain, oxidative stress markers, and clinical pregnancy rate in women with endometriosis: a systematic review and meta-analysis...
Published 2025“…The results showed that antioxidant supplementation significantly alleviated pelvic pain (continuous outcomes: SMD = −2.68; p < 0.00001; binary outcomes: RR = 9.31; p < 0.0001), dysmenorrhea (SMD = −1.77; p = 0.01; RR = 2.39; p = 0.03), and dyspareunia (SMD = −2.33; p = 0.01; RR = 5.40; p = 0.003), and significantly decreased peripheral blood malondialdehyde (MDA) levels (SMD = −7.58; p = 0.001). …”
-
19916
Image2_Integrating anoikis and ErbB signaling insights with machine learning and single-cell analysis for predicting prognosis and immune-targeted therapy outcomes in hepatocellula...
Published 2024“…Background<p>Hepatocellular carcinoma (HCC) poses a significant global health challenge due to its poor prognosis and limited therapeutic modalities. …”
-
19917
The efficacy of dexamethasone compared to prednisone/prednisolone for the management of pediatric patients with acute exacerbation of asthma: a systematic review and meta-analysis
Published 2025“…Moreover, dexamethasone decreased the risk of vomiting (RR 0.39, 95% CI (0.25, 0.59), I<sup>2</sup> = 26.62%) compared to prednisone-prednisolone.…”
-
19918
Data Sheet 1_Primary care and specialist physicians’ prescribing preferences for concurrent probiotic-antibiotic therapy: a multinational clinical practice survey across 13 countri...
Published 2025“…<p>Antibiotic-induced intestinal microbiota disruption represents a significant clinical concern, yet physician practices regarding concurrent probiotic supplementation remain poorly characterized across international healthcare systems. …”
-
19919
Supplementary file 1_The association of dietary pattern with the risk of common chronic diseases in Shandong Province, China: a cross-sectional study.docx
Published 2025“…Background<p>Chronic diseases have emerged as a significant public health challenge, impacting the well-being of the Chinese populace, despite scant research exploring the influence of dietary factors on these conditions. …”
-
19920
Image 9_A zebrafish model of crim1 loss of function has small and misshapen lenses with dysregulated clic4 and fgf1b expression.tiff
Published 2025“…Crim1 encodes a type I transmembrane protein that is expressed at the cell membrane of lens epithelial and fiber cells at the stage of lens pit formation. Decreased Crim1 expression in the mouse reduced the number of lens epithelial cells and caused defective adhesion between lens epithelial cells and between the epithelial and fiber cells.…”