Genotoxic Mechanisms of Erythrophleum suaveolens Stem Bark Extracts and Fractions in MCF-7 Breast Cancer Cells via Mitochondrial and Non-Mitochondrial Pathways حسب Lateef Sulaimon (21706283)

"…After 72 hours, ESSB-treated MCF-7 cells showed a significant (p < 0.05) increase in DNA fragmentation and comet tail DNA percentages (flavonoids induced a 1.21-fold increase in comet tail length). …"

Data Sheet 1_Hemerocallis citrina Baroni leaf total phenol alleviates depressive-like behaviors via modulating “microbiota-gut-brain” axis in chronic unpredictable mild stress -ind... حسب Yanping Wang (275956)

"…Additionally, HLTP reversed 63 CUMS-induced abnormal serum metabolites, primarily affecting tryptophan metabolism, niacin and nicotinamide metabolism, and porphyrin metabolism. Significant correlations were observed among gut microbial composition, serum metabolite levels, biochemical indices, and behavioral outcomes.…"

Table 1_High intake of n-6 polyunsaturated fatty acid exacerbates non-alcoholic steatohepatitis by the involvement of multiple metabolic pathways.docx حسب Jian-Tong (21583487)

"…Aggravation of NASH in D1 was accompanied by reduced levels of 15-deoxy-Δ12,14-prostaglandin J2 and PPAR-γ, weakening anti-inflammatory effects and lipid metabolism. Decreased CYP2J3 expression along with reduced PPAR-α levels, likely contributed to reduced anti-inflammatory EET levels, while elevated soluble epoxide hydrolase increased pro-inflammatory dihydroxyeicosatrienoic acids. …"

Green Fabrication of Biobased and Degradable Poly(lactic acid)/Poly(butylene succinate) Open-Cell Foams for Highly Efficient Oil–Water Separation with Ultrafast Degradation حسب Jie Yuan (208425)

"…Compared to PLA/PBS9 foam with a similar expansion ratio and open-cell content, the adsorption capacity of PLA/PBS6 has increased from 18.8 to 24.5 g/g, but the adsorption rate constant decreased. …"

Ameliorating role of co-administration of granulocyte colony stimulating factor and sodium bicarbonate on the skeletal muscle of a rat model of chronic kidney disease (A histologic... حسب Fayza E. Ahmed (20487163)

"…The CKD group revealed a significant increase in MDA and TNF-α. Furthermore, features of renal injury, muscle degenerative changes, increased collagen and decreased CD34 and myogenin expression were observed. …"

Assessing the biochemical and genotoxic effects of low intensity 2.45GHz microwave exposure on <i>Arabidopsis thaliana</i> plants حسب Mudalige Don Hiranya Jayasanka Senavirathna (19797836)

"…Conversely, catalase activity decreased. Photosystem efficiency remained unchanged, while non-photochemical quenching increased. …"

Table 1_Do the diagnosis-related group payment reforms have a negative impact?—an empirical study from Western China.xlsx حسب Jia-Yi Wang (490704)

"…In the treatment group hospitals, the primary beneficiaries of the reform were urban employees’ basic medical insurance patients, whose costs decreased by 4.9% (p < 0.01), with a non-significant effect on out-of-pocket payment patients and free medical care patients; the hospitals in the treatment group tended to reduce the use of Chinese medicine unique diagnostic and therapeutic means and increase the proportion of western medicine treatments under the pressure of the supremacy of costs.…"

<b>Species richness, composition and dominance of core and climate relicts of African Miombo woodlands</b> حسب Justice Muvengwi (22631075)

"…Our results revealed a pattern where species richness, the Shannon Wiener index, and evenness increased with decreasing relict size. Interestingly, evenness declined from juvenile to adult stages within sites, suggesting changes in species composition over time. …"

Image 1_STZ-induced hyperglycemia differentially influences mitochondrial distribution and morphology in the habenulointerpeduncular circuit.tiff حسب Mohammad Jodeiri Farshbaf (20466956)

"…BODIPY staining intensity was unchanged in the vMHb of STZ-treated mice but increased in the IPN and VTA and decreased in the LHb at 12 weeks. …"

Effects of task optimization on pareidolia representations in CNNs. حسب Pranjul Gupta (20623949)

"…Conversely, in CNNs lacking object categorization training (Panels B, C), this similarity was weak, only reaching significance at early layers, and decreased across layers. …"

Supplementary file 1_Spatial-temporal evolution characteristics and driving factors of carbon emission prediction in China-research on ARIMA-BP neural network algorithm.pdf حسب Sanglin Zhao (20915732)

"…The results show that: (1) From 2000 to 2035, China’s total carbon emissions increased year by year, but the growth rate of carbon emissions gradually decreased; The carbon emission structure is “secondary industry > residents’ life > tertiary industry > primary industry”, and the growth rate of carbon in secondary industry and residents’ life is faster, while the change trend of primary industry and tertiary industry is smaller; (2) The spatial distribution of carbon emissions in China’s provinces presents a typical pattern of “eastern > central > western” and “northern > southern”, and the carbon emission centers tend to move to the northwest; (3) The regions with high level of digital economy, advanced industrial structure and new quality productivity have relatively less carbon emissions, which has significant group difference effect; (4) The intensity effect of energy consumption is the main factor driving the continuous growth of carbon emissions, while the per capita GDP and the structure effect of energy consumption are the main factors restraining carbon emissions, while the effects of industrial structure and population size are relatively small. …"

Data Sheet 1_Evolving trends and burden of idiopathic epilepsy among children (0–14 years), 1990–2021: a systematic analysis for the Global Burden of Disease study 2021.zip حسب Fulai Tu (15364489)

"…Data collation and visualizations were conducted using R software, with statistical significance established at a p-value threshold of 0.05.…"

Data Sheet 1_An analysis of the global burden of childhood and adolescent asthma attributable to high BMI: 1990–2021.pdf حسب Xinhui Zhang (1624039)

"…Statistical analysis showed a significant correlation between SDI and asthma burden (P < 0.001), with the overall disease burden increasing as SDI rose. …"

Table_1_Hyperthyroidism, hypothyroidism, thyroid stimulating hormone, and dementia risk: results from the NHANES 2011–2012 and Mendelian randomization analysis.DOCX حسب Xixi Sheng (19932165)

"…</p>Conclusion<p>This study provides evidence of a nonlinear relationship between TSH and FT4 concentrations and cognitive function, with hyperthyroidism decreasing the risk of dementia and VaD, hypothyroidism increasing the risk of dementia and VaD, and elevated serum TSH concentrations increasing the risk of AD. …"

Data Sheet 1_Eupalinolide A inhibits cancer progression and induces ferroptosis and apoptosis by targeting the AMPK/mTOR/SCD1 signalling in non-small cell lung cancer.docx حسب Yonghui Zhang (279832)

"…EA treatment (25 mg/kg) markedly inhibited tumour growth in vivo in a xenograft model; both tumour weight and tumour volume decreased by more than 60% without significantly affecting the body weight of tumour-bearing mice.…"

Data Sheet 1_A multimodal approach for establishing ACTL6A and ERCC1 as chemoresistance genes in locally advanced head and neck cancer.docx حسب Raushan Kumar Chaudhary (15664043)

"…The median expressions of ERCC1 were significantly increased (p < 0.001) after 50% (0.19) and 100% CRT (0.23) compared to the baseline value (0.14), whereas ACTL6A expression decreased from 4.77 to 3.87 after 50% CRT (p < 0.05) and increased to 5.43 after 100% CRT. …"

Effect of curcumin on methotrexate-induced ovarian damage and follicle reserve in rats: the role of PARP-1 and P53 حسب Mete Keçeci (20479508)

"…Expressions of p53 and Poly [ADP-ribose] polymerase 1 (PARP-1) increased significantly in the MTX group compared to the other groups (<i>p</i> < 0,05).…"

Video 1_Kininogen enhances seizure susceptibility in mice possibly through bradykinin-induced modulation of calcium transients in glutamatergic and GABAergic neurons.mp4 حسب Arijit Ghosh (1304952)

"…Overexpression of kininogen and exogenous bradykinin administration significantly increased pentylenetetrazole-induced seizure susceptibility in mice. …"

Table 1_Determining the efficacy and safety of acupuncture for the treatment of menstrual migraine: an updated systematic review and meta-analysis.docx حسب Qiqi Wu (4895728)

"…Compared with control interventions, acupuncture significantly reduced VAS scores, decreased the frequency and duration of migraine attacks, and improved response rates, as well as HIT-6 and MHI scores. …"

Image 1_Polygonatum sibiricum polysaccharides enhance pancreatic β-cell function in diabetic zebrafish by mitigating mitochondrial oxidative damage via the AMPK-SIRT1 pathway.tif حسب Fan Lin (625737)

"…Antioxidant enzyme activities (SOD, CAT) increased, while oxidative stress markers (MDA) and inflammatory cytokines (IL-1β, IL-6, TNF-α) decreased (p < 0.01). …"