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significantly larger » significantly lower (Expand Search), significantly smaller (Expand Search), significantly higher (Expand Search)
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421
Presentation 3_A phase 2a double-blind, placebo-controlled, randomized clinical trial evaluating the efficacy and safety of NuGel, a novel topical GPCR19-mediated inflammasome inhi...
Published 2025“…</p>Results<p>NuGel (0.3% [Nu0.3] and 0.5% [Nu0.5]) was well-tolerated, with no adverse drug reactions or serious adverse events. Nu0.3 showed a significant decrease in EASI score from baseline (-12.2%, [-30.3%, 5.9%], p = 0.04). …”
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422
Data Sheet 1_A phase 2a double-blind, placebo-controlled, randomized clinical trial evaluating the efficacy and safety of NuGel, a novel topical GPCR19-mediated inflammasome inhibi...
Published 2025“…</p>Results<p>NuGel (0.3% [Nu0.3] and 0.5% [Nu0.5]) was well-tolerated, with no adverse drug reactions or serious adverse events. Nu0.3 showed a significant decrease in EASI score from baseline (-12.2%, [-30.3%, 5.9%], p = 0.04). …”
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423
Data Sheet 2_A phase 2a double-blind, placebo-controlled, randomized clinical trial evaluating the efficacy and safety of NuGel, a novel topical GPCR19-mediated inflammasome inhibi...
Published 2025“…</p>Results<p>NuGel (0.3% [Nu0.3] and 0.5% [Nu0.5]) was well-tolerated, with no adverse drug reactions or serious adverse events. Nu0.3 showed a significant decrease in EASI score from baseline (-12.2%, [-30.3%, 5.9%], p = 0.04). …”
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424
Presentation 2_A phase 2a double-blind, placebo-controlled, randomized clinical trial evaluating the efficacy and safety of NuGel, a novel topical GPCR19-mediated inflammasome inhi...
Published 2025“…</p>Results<p>NuGel (0.3% [Nu0.3] and 0.5% [Nu0.5]) was well-tolerated, with no adverse drug reactions or serious adverse events. Nu0.3 showed a significant decrease in EASI score from baseline (-12.2%, [-30.3%, 5.9%], p = 0.04). …”
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425
Table 1_Inhibitory control in the sober state as a function of alcohol sensitivity: a pilot functional magnetic resonance imaging (fMRI) study.docx
Published 2025“…Based on these preliminary findings, future studies with larger samples are warranted to determine the extent to which domain-general IC performance associated with fronto-cortico-striatal IC circuit activation contributes to the alcohol use pathophysiology, and whether therapeutic interventions (e.g., non-invasive brain stimulation) targeting fronto-cortico-striatal IC circuitry may decrease AUD symptomatology.…”
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426
Table 2_Inhibitory control in the sober state as a function of alcohol sensitivity: a pilot functional magnetic resonance imaging (fMRI) study.docx
Published 2025“…Based on these preliminary findings, future studies with larger samples are warranted to determine the extent to which domain-general IC performance associated with fronto-cortico-striatal IC circuit activation contributes to the alcohol use pathophysiology, and whether therapeutic interventions (e.g., non-invasive brain stimulation) targeting fronto-cortico-striatal IC circuitry may decrease AUD symptomatology.…”
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427
<b>The moderating effect of financial literacy on risk preferences and time preferences</b>
Published 2025“…Additionally, the study concluded that time preferences significantly moderate financial literacy. An increase in financial literacy is associated with a decrease in time preferences, indicating that as financial literacy rises, subjects become more patient. …”
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428
Effect of appetite suppressants on head-weaving stereotypy in female rats.
Published 2025“…However, unlike males (CV = 37.8%), there was significant variability between subjects (CV = 49%) and across days. …”
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429
Data_Sheet_1_Subthreshold amyloid deposition, cerebral small vessel disease, and functional brain network disruption in delayed cognitive decline after stroke.docx
Published 2024“…Given the limited number of patients and potential residual confounding, our results should be considered hypothesis-generating and need replication in larger cohorts in the future.</p>…”
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430
E4 assessment of physiological measures (Kondaurova et al., 2024)
Published 2024“…Children self-reported a significant increase in LE over time. However, their physiological measures demonstrated a trend indicating a decrease in LE. …”
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431
S5 Fig - The human medial temporal lobe represents memory items in their ordinal position in both declarative and motor memory domains
Published 2025“…Planned pairwise comparisons indicate that in M1 and PMC, similarity values of the diagonal (i.e., lag 0, same position) were significantly larger than all other lags (i.e., lag 0 > all other lags, all <i>p</i><sub><i>corr</i></sub> < .05), while in the PHC, the diagonal was only significantly larger than lag 2 (<i>p</i><sub><i>corr</i></sub> < .05). …”
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432
Changes in the effective optical zone following hyperopic keratorefractive lenticule extraction
Published 2025“…ΔEOZ/POZ and ΔEOZ/PTZ were significantly larger at the late than the early postoperative stage in both groups (<i>p</i> < 0.001), with a larger ΔEOZ/POZ value in group B than that in group A at both stages (<i>p</i> < 0.001). …”
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433
Table 2_The cerebral metabolic mechanism of group computer magnanimous therapy based on magnetic resonance spectroscopy: effects on improving magnanimous-enterprising levels of lun...
Published 2024“…Significant increases in NAA/Cr levels were observed in the right amygdala, and significant decreases in mI/Cr levels were observed in the right cingulate gyrus in the GCMTG. …”
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434
Table 1_The cerebral metabolic mechanism of group computer magnanimous therapy based on magnetic resonance spectroscopy: effects on improving magnanimous-enterprising levels of lun...
Published 2024“…Significant increases in NAA/Cr levels were observed in the right amygdala, and significant decreases in mI/Cr levels were observed in the right cingulate gyrus in the GCMTG. …”
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435
Reliable high-PAP-1-loaded polymeric micelles for cancer therapy: preparation, characterization, and evaluation of anti-tumor efficacy
Published 2025“…Molecular simulations revealed that PAE’s tertiary amine protonation affected the self-assembly process, modifying hydrophobicity and resulting in larger, loosely packed particles. Furthermore, compared to free PAP-1 or PAP-1 combined with MDR inhibitors, PAP-1-loaded micelles significantly enhanced cytotoxicity and apoptosis induction in Jurkat and B16F10 cells, through mechanisms involving decreased mitochondrial membrane potential and elevated caspase-3 activity. …”
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436
Table 1_A real-world study of polyenyl phosphatidylcholine in the management of patients with metabolic dysfunction-associated fatty liver disease in China clinical practice.docx
Published 2025“…In the PPC group, baseline alanine transaminase (ALT) levels decreased at 12- and 24-weeks compared to those of the control group, but results were not significant. …”
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437
Supplementary Material for: Seraph-100 hemoperfusion for management of severe COVID-19: Assessment of serum and plasma analytes pre- and post-filtration
Published 2024“…However, multiple circulating proteins with roles in inflammation, endothelial/epithelial damage and/or angiogenesis decreased significantly across the filter. Larger prospective trials will be required to determine if such transient reductions translate into improved patient outcomes. …”
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438
Table 1_Rainfall distribution variability controls surface but not belowground litter decomposition in a semi-arid shrubland.docx
Published 2025“…</p>Results<p>Decomposition of belowground litter was consistently higher than that of surface litter over the entire field-incubation process. Mass loss significantly decreased in surface litter but not in belowground litter due to the lower frequency and larger amount of precipitation compared to the control treatment. …”
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439
Model-derived results show increased social following in individuals with disrupted utility-based risky decision-making.
Published 2024“…<p><b>(a)</b> Parameter estimates across all trials showed that individuals with insula or dACC lesions had significantly larger ω<sub>follow</sub> estimates than non-lesioned control participants (NC; NC vs insula: <i>P</i> = 0.036; NC vs dACC: <i>P</i> = 0.025; dACC vs insula: <i>P</i> = 0.89, BF<sub>null</sub> = 2.28), indicating that the lesion participants were more likely to conform with others’ choices during decision-making in a social context. …”
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440
Supplementary Material for: Association of platelet count and mean platelet volume with fish intake frequency: Implication for the cardioprotective effect of fish intake
Published 2025“…Naturally, though, n-3 PUFA intake significantly increased with increased fish intake frequency (p < 0.0001). …”