Image1_Oleic acid attenuates asthma pathogenesis via Th1/Th2 immune cell modulation, TLR3/4-NF-κB-related inflammation suppression, and intrinsic apoptotic pathway induction.tif by Soon-Young Lee (4721136)

“…The incidence is expected to increase as the average life expectancy increases, highlighting asthma as a significant health challenge in an aging society. The etiology of asthma is linked to an imbalance of Th1 and Th2 cells, respiratory inflammation, and pulmonary cell proliferation. …”

Data Sheet 1_The role of ATP6V0D2 in breast cancer: associations with prognosis, immune characteristics, and TNBC progression.docx by Jingyu Zhang (256203)

“…Mutation analysis revealed that PIK3CA, linked to decreased OS, exhibited a higher mutation rate in the ATP6V0D2 high expression group. …”

Data Sheet 1_Association of oxidative balance score with all-cause and cardiovascular mortality among patients with cardio-renal-metabolic disease.docx by Yucui Lin (21598376)

“…Moreover, Higher OBS quartiles were linked to a decreased risk of cardiovascular mortality, while no significant reduction was observed in the lower quartiles [model 3: Q2, Q3, Q4: aHR (95CI%) = 0.96(0.77–1.19), 0.78 (0.63–0.97), 0.70 (0.53–0.93), respectively; P for trend = 0.003]. …”

Data Sheet 1_Therapeutic efficacy of a galactoglucan from Pleurotus citrinopileatus in constipation: modulation of aquaporin signaling and intestinal barrier.pdf by Yi Gao (112914)

“…The oral administration of PCP-g resulted in a significant reduction in constipation symptoms, as indicated by an increase in fecal water content, normalization of pellet formation, enhancement of total fecal mass, decreased latency to the first stool, and improved intestinal propulsion. …”

Data Sheet 1_The multivalent passive immune-protective vaccines of egg yolk immunoglobulin Y derived from live or inactivated Pseudomonas anguilliseptica against aquaculture pathog... by Pan Cui (5726669)

“…Furthermore, the structures of the kidney, spleen, and intestinal tissues were intact, and the expression of p53 and γH2A.X decreased in the kidney.</p>Conclusion<p>L-PA-IgY and I-PA-IgY can resist multiple bacterial infections and have immunoprotective effects with no significant differences. …”

Causal associations between gut <i>Bifidobacteriaceae</i> and transplant failure: a Mendelian randomization study by Han Yan (126662)

“…</p> <p><b>Results:</b> The abundance of <i>Bifidobacteriaceae</i> demonstrated a significant causal relationship with transplant failure (inverse variance weighted [IVW] <i>p</i> = 0.049, OR = 0.658, 95% CI: 0.433–0.998), but was not related to the risk of transplantation status (IVW <i>p</i> > 0.200). …”

Table 1_Coffee consumption as a double-edged sword for serum lipid profile: findings from NHANES 2005–2020.docx by Chaoyue Mo (21684056)

“…Although these changes were statistically significant, their clinical relevance may vary depending on individual cardiovascular risk profiles.…”

SEAwise synthetic summary report of the findings of WP4 on changes to the ecosystem impacts of fishing in response to spatial management for online tool by Anna Rindorf (6217391)

“…While the attainment of GES could also be found in scenarios with closed areas, this was generally restricted to the indicators at which the closure was aimed while other indicators worsened.</p><p dir="ltr">Decreasing fishing effort to levels compatible with FMSY-min resulted in slightly but not significantly higher average landings in the Adriatic and western Ionian Sea and the North Sea under current climate where currently overfished gadoid stocks were rebuilt in the simulations. …”

Table 1_Association between serum anion gap trajectory and mortality in hospitalized patients with sepsis: an analysis of the MIMIC-IV database.docx by Lijuan Jing (20431757)

“…Subgroup analysis revealed a significant interaction between AG trajectories and heart failure status. …”

Table 1_Associations between gut microbiota and diet composition of three arid-adapted rodent species from the Inner Mongolia grassland.doc by Muha Cha (4002941)

“…In contrast, the consumption of animal-based foods significantly decreased microbial diversity. This finding suggests a potential link between the host’s genetic background, dietary composition, and the gut microbiota.…”

Data Sheet 1_Cross-species analysis of FcγRIIa/b (CD32a/b) polymorphisms at position 131: structural and functional insights into the mechanism of IgG- mediated phagocytosis in hum... by William D. Tolbert (7870697)

“…In contrast, allele-specific effects in macaques were highly significant; the macaque P¹³¹ variant showing uniformly reduced IgG affinity. …”

Table_1_Characterization of the microbial communities and their correlations with volatile flavor compounds and physicochemical factors in Bashang suancai, a traditional Chinese pi... by Yuan Liu (88411)

“…The bacterial community diversity decreased significantly following 7 days of fermentation. …”

Supplementary file 1_Prolonged effect of antibiotic therapy on the gut microbiota composition, functionality, and antibiotic resistance genes’ profiles in healthy stool donors.zip... by Ramin Karimianghadim (21288299)

“…Functional analyses revealed alterations in housekeeping genes critical for energy production and biosynthesis, with no direct links to key health-related pathways. Antibiotics also disrupted viral populations, decreasing diversity and increasing crAssphage abundance, reflecting disrupted host-bacteriophage dynamics. …”

Supplementary file 1_Ecosystem carbon storage and carbon metabolizing microorganisms in three types of grasslands on the Qinghai-Tibet Plateau.docx by Qian Liu (135614)

“…The relative abundance of carbon-fixing microorganisms Thiobacillus, Mesorhizobium, Azospirillum, and Methylibium significantly increased grassland carbon storage, while the relative abundance of chitinase-producing microorganisms Cellulomonas and Stenotrophomonas significantly decreased it.…”

Correlation analyses between studied genes. by Marwa A. Ali (11973086)

“…In comparison, <i>miR374b-5p</i> showed sensitivity and specificity of around 85% in distinguishing COVID-19 patients from controls. No significant association was detected between target genes and radiological severity indices.…”

Primers used in q-PCR. by Marwa A. Ali (11973086)

“…In comparison, <i>miR374b-5p</i> showed sensitivity and specificity of around 85% in distinguishing COVID-19 patients from controls. No significant association was detected between target genes and radiological severity indices.…”

Data Sheet 1_A machine learning model for predicting the risk of diabetic nephropathy in individuals with type 2 diabetes mellitus.docx by Tingting Li (10553)

“…Introduction<p>Diabetic kidney disease (DKD) represents the predominant form of chronic kidney disease (CKD) linked with diabetes mellitus. The application of artificial intelligence holds promise for delaying renal deterioration and decreasing treatment expenses by facilitating early detection and intervention. …”

Data Sheet 1_Polyphenol-mediated microbiome modulation in STEMI patients: a pilot study.zip by Argul Issilbayeva (21398168)

“…Polyphenol supplementation significantly decreased the Firmicutes/Bacteroidetes ratio (p = 0.04) and increased beneficial bacteria such as Roseburia (p = 0.01), Agathobaculum sp. …”

Table 1_Elucidating the causal relationship between 486 genetically predicted blood metabolites and the risk of gastric cancer: a comprehensive Mendelian randomization analysis.xls... by Lei Qian (292302)

“…</p>Results<p>The MVMR analysis revealed a significant association between genetically predicted elevated levels of tryptophan (odds ratio [OR] = 0.523, 95% confidence interval [CI] = 0.313–0.872, p = 0.013), nonadecanoate (19:0) (odds ratio [OR] = 0.460, 95% confidence interval [CI] = 0.225–0.943, p = 0.034), and erythritol (odds ratio [OR] = 0.672, 95% confidence interval [CI] = 0.468–0.930, p = 0.016) with a decreased risk of gastric cancer. …”

Stepwise increments in stimulus amplitude alter the information content of post-EOD spike distributions. by Alejo Rodríguez-Cattáneo (19713314)

“…Significance after Holm-Bonferroni adjustment for 8 comparisons: 0.05.…”