Image 3_Scalability of spheroid-derived small extracellular vesicles production in stirred systems.tif حسب Thibaud Dauphin (21196820)

"…Implementing upstream processes in a chemically defined media in stirred-tank bioreactors (STBr) is mandatory to closely control the cell environment, and to scale-up production, but it remains a significant challenge for anchorage-dependent cells.…"

Image 1_Scalability of spheroid-derived small extracellular vesicles production in stirred systems.tif حسب Thibaud Dauphin (21196820)

"…Implementing upstream processes in a chemically defined media in stirred-tank bioreactors (STBr) is mandatory to closely control the cell environment, and to scale-up production, but it remains a significant challenge for anchorage-dependent cells.…"

Data Sheet 1_Association of advanced lung cancer inflammation index with all-cause and cardiovascular mortality in US patients with asthma.pdf حسب Jiatao Li (10033795)

"…Background<p>Asthma poses a significant global health challenge, representing a chronic respiratory disorder marked by airway inflammation. …"

Image 1_Application and validation of the machine learning-based multimodal radiomics model for preoperative prediction of lateral lymph node metastasis in papillary thyroid carcin... حسب Jia-Wei Feng (10754067)

"…</p>Results<p>Logistic regression identified five independent clinical risk factors: maximum tumor diameter, multiple lesions, upper pole location, decreased monocyte count, and lower lymphocyte-to-monocyte ratio (LMR). …"

Table 1_Influence of indigenous non-Saccharomyces yeast strains on the physicochemical and sensory properties of wine fermentation: a promising approach to enhancing wine quality.d... حسب Sathivel Thivijan (20393742)

"…The combined attributes of H. uvarum higher alcohol content, enhanced fruity notes, improved clarity, lower acetic acid (0.52 ± 0.03 g L⁻¹), and significant residual sugar (162.37 ± 2.48 g L⁻¹) make it a promising candidate for improving the overall quality of regional wines. …"

Data Sheet 1_Synchronized nutrition fertilizer improves soil microbial diversity and sugarcane yield through agrochemical and enzymatic regulation.docx حسب Xiuxiu Qi (22354858)

"…</p>Results<p>Results showed that yield, °Brix in the SNFert, even with 15% and 25% less fertilizer input, were no significant differences with those of CF. Specifically, SNF1 increased sugarcane yield and tillers by 6.84% and 18.63%, raised pH and urease by 0.40 units and 2.29 times, reduced Nmin and EC by 81.69% and 77.69% with 15% lower fertilizer input, respectively. …"

Table 1_Eculizumab for the acute attack of neuromyelitis optica spectrum disorder.docx حسب Qingqing Zhuang (22109089)

"…Following eculizumab, six of the seven ON patients showed significant improvements in visual acuity and visual fields, with five recovering to near-normal or pre-attack vision. …"

Image 2_Scalability of spheroid-derived small extracellular vesicles production in stirred systems.tif حسب Thibaud Dauphin (21196820)

"…Implementing upstream processes in a chemically defined media in stirred-tank bioreactors (STBr) is mandatory to closely control the cell environment, and to scale-up production, but it remains a significant challenge for anchorage-dependent cells.…"

DataSheet1_Neuroprotective effect of Bouvardia ternifolia (Cav.) Schltdl via inhibition of TLR4/NF-κB, caspase-3/Bax/Bcl-2 pathways in ischemia/reperfusion injury in rats.PDF حسب Yury Maritza Zapata-Lopera (19725616)

"…They prevent the activation of iNOS and nNOS, reducing harmful reactive oxygen and nitrogen species, and boosting antioxidant enzymes like catalase and superoxide dismutase. This lowers oxidative stress and decreases the expression of proteins and genes linked to cell death, such as Bax, Bcl-2, and caspase-3. …"

Ameliorating role of co-administration of granulocyte colony stimulating factor and sodium bicarbonate on the skeletal muscle of a rat model of chronic kidney disease (A histologic... حسب Fayza E. Ahmed (20487163)

"…The CKD group revealed a significant increase in MDA and TNF-α. Furthermore, features of renal injury, muscle degenerative changes, increased collagen and decreased CD34 and myogenin expression were observed. …"

Data Sheet 1_Deep learning-based image reconstruction benefits diffusion tensor imaging for assessing severity of depression.docx حسب Yuanyuan Cui (276987)

"…Compared to patients with mild-to-moderate depression, those with severe depression showed lower FA values in the right corticospinal tract (CST) on ORI DTI. …"

Table 1_Methodological approaches to survey complex ice cave environments - the case of Dobšiná (Slovakia).docx حسب Katarína Pukanská (20431835)

"…Increased precipitation, the rise in year-round surface temperatures, and the gravity cause significant shape changes in the ice filling.</p>Methods<p>This paper describes modern technological tools to comprehensively survey and evaluate interannual changes in both the floor and wall of the underground ice body. …"

Changes in functional connectivity between NREM and REM – comparison of in vivo experimental and in silico modeling data. حسب Michael Satchell (21560808)

"…ACh⁺ dynamics causes broad pruning of weaker connections with the SF population, shifting the distribution towards lower functional connectivity values (lower z-scores) as compared to ACh^– state (center). …"

Table 1_Novel integrated approach modeling proanthocyanidins and bacteriophages to combat multidrug Salmonella Typhimurium in challenged broilers.docx حسب Hanan S. Al-Khalaifah (12864938)

"…GSOPs+BP fortified group exhibited higher cecal beneficial bacteria counts (Bacteroides, Firmicutes, Lactobacillus, and Bifidobacterium species), lower cecal harmful bacteria loads (Escherichia, Enterobacteriaceae, and Clostridium clusters I and IV), decreased serum oxidative markers [H₂O₂, reactive oxygen species (ROS), and malondialdehyde (MDA)], and increased serum antioxidant enzymes [superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GSH-Px)]. …"

Ictogenic changes in input correlation and adaptation gains are associated with increased dynamical variability during baseline activity. حسب Scott Rich (9873638)

"…Plotted values are mean SD over 50 independent 200 s simulations. SLEs are significantly more frequent for each displayed <i>c</i> value in comparison to the red <i>c</i> = 0.01 case (<i>p</i> < 0.05, two sample t-test). …"

Data Sheet 1_Comparison of adverse events between intensity-modulated radiation therapy and tomotherapy for early stage breast cancer: a retrospective cohort study.pdf حسب Yan Xia (534241)

"…A comparison of adverse events between the TOMO and IMRT groups showed no significant differences in localized edema, sore throat, tracheal mucositis, nausea, oral mucositis, and the IMRT groups. …"

Table 1_Forest bathing enhances sleep, mood, and immunity: insights from low-latitude evergreen broad-leaved forests.xlsx حسب Xiangheng Dai (21684431)

"…Sleep quality improved with decreased AIS scores during the intervention and lower SRSS scores up to one month post-intervention. …"

Data Sheet 1_Effects of drospirenone and ethinylestradiol tablets (II) combined with metformin on the composition of gut microbiota in polycystic ovary syndrome with insulin resist... حسب Yanglu Liu (22417861)

"…Characteristics of gut microbiota: before treatment, there was no significant difference in α and β diversity between PCOS-NIR group and PCOS-IR group. …"

Table 1_A national population-based study of mortality and risk factors in COVID-19-hospitalized patients in Spain (2020–2021).docx حسب José-Manuel Ramos-Rincón (10428656)

"…IHM rose with age, from 0.8% in patients aged 18–39 to 31.7% in those ≥80 years (p < 0.001), but significant decreases were observed across all age groups after vaccination, especially in those ≥80 years (AOR: 0.76, 95% CI: 0.75–0.79, p < 0.001). …"

The protective effects of neferine against paracetamol-induced liver injury are associated with the activation of SIRT1/Nrf2/HO-1 signaling pathway and inhibition of NF-kappa B/TNF... حسب Mohammed A. Altowijri (22461945)

"…<p>Drug-induced hepatotoxicity is a significant public health issue that influences the development of novel pharmaceutical therapies and the retraction of numerous promising medications from the market. …"