Search alternatives:
significantly mediate » significantly mediated (Expand Search), significantly predicted (Expand Search), significantly mitigated (Expand Search)
significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
mediate decrease » mean decrease (Expand Search), mediated defense (Expand Search)
significantly mediate » significantly mediated (Expand Search), significantly predicted (Expand Search), significantly mitigated (Expand Search)
significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
mediate decrease » mean decrease (Expand Search), mediated defense (Expand Search)
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18541
Image 1_PCP4 inhibits the progression of prostate cancer through Ca2+/CAMKK2/AMPK/AR pathway.jpeg
Published 2025“…A series of molecular and biochemical experiments were carried out in PCa cell lines to investigate the mechanism underlying PCP4-mediated tumor suppression.</p>Results<p>(1) PCP4 gene loss occurs at high frequency in PCa patients, and decreased expression of PCP4 correlates with poor prognosis of PCa, particularly CRPC development; (2) TMPRSS2-ERG fusion frequently co-occurs with PCP4 deletion; (3) PCP4 suppresses prostate cancer progression in vitro and in vivo; (4) PCP4 is an androgen receptor (AR) suppressed gene; (5) PCP4 was involved in the stabilization of CAMKK2 protein; (6) PCP4 inhibits PCa progression by regulating Ca<sup>2+</sup>/CAMKK2/AMPK/AR signaling axis.…”
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18542
Table 1_PCP4 inhibits the progression of prostate cancer through Ca2+/CAMKK2/AMPK/AR pathway.xlsx
Published 2025“…A series of molecular and biochemical experiments were carried out in PCa cell lines to investigate the mechanism underlying PCP4-mediated tumor suppression.</p>Results<p>(1) PCP4 gene loss occurs at high frequency in PCa patients, and decreased expression of PCP4 correlates with poor prognosis of PCa, particularly CRPC development; (2) TMPRSS2-ERG fusion frequently co-occurs with PCP4 deletion; (3) PCP4 suppresses prostate cancer progression in vitro and in vivo; (4) PCP4 is an androgen receptor (AR) suppressed gene; (5) PCP4 was involved in the stabilization of CAMKK2 protein; (6) PCP4 inhibits PCa progression by regulating Ca<sup>2+</sup>/CAMKK2/AMPK/AR signaling axis.…”
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18543
Table 2_PCP4 inhibits the progression of prostate cancer through Ca2+/CAMKK2/AMPK/AR pathway.xlsx
Published 2025“…A series of molecular and biochemical experiments were carried out in PCa cell lines to investigate the mechanism underlying PCP4-mediated tumor suppression.</p>Results<p>(1) PCP4 gene loss occurs at high frequency in PCa patients, and decreased expression of PCP4 correlates with poor prognosis of PCa, particularly CRPC development; (2) TMPRSS2-ERG fusion frequently co-occurs with PCP4 deletion; (3) PCP4 suppresses prostate cancer progression in vitro and in vivo; (4) PCP4 is an androgen receptor (AR) suppressed gene; (5) PCP4 was involved in the stabilization of CAMKK2 protein; (6) PCP4 inhibits PCa progression by regulating Ca<sup>2+</sup>/CAMKK2/AMPK/AR signaling axis.…”
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18544
Table 3_PCP4 inhibits the progression of prostate cancer through Ca2+/CAMKK2/AMPK/AR pathway.xlsx
Published 2025“…A series of molecular and biochemical experiments were carried out in PCa cell lines to investigate the mechanism underlying PCP4-mediated tumor suppression.</p>Results<p>(1) PCP4 gene loss occurs at high frequency in PCa patients, and decreased expression of PCP4 correlates with poor prognosis of PCa, particularly CRPC development; (2) TMPRSS2-ERG fusion frequently co-occurs with PCP4 deletion; (3) PCP4 suppresses prostate cancer progression in vitro and in vivo; (4) PCP4 is an androgen receptor (AR) suppressed gene; (5) PCP4 was involved in the stabilization of CAMKK2 protein; (6) PCP4 inhibits PCa progression by regulating Ca<sup>2+</sup>/CAMKK2/AMPK/AR signaling axis.…”
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18545
PDLB - Balance Sheet
Published 2024“…The combination of flat / decreasing costs and double-digit asset growth is very favorable for expense leverage.…”
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18546
Unveiling the molecular legacy of transient insulin resistance: Implications for hepatic metabolic adaptability (Sup Tables). Berthier et al. J. Hepatol. 2025
Published 2025“…</p><h3>Results</h3><p dir="ltr">Our study shows that temporarily blocking the insulin receptor in young mice leads to later-life liver issues by hindering PPARα-mediated adaptation to a high-fat diet. This is linked to decreased histone active marks at PPARα sites and reduced endogenous PPARα ligands. …”
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18547
Supplementary Material for: The effectiveness of regionalization of perinatal care and specific facility-based interventions: A systematic review
Published 2024“…Results: Implementation of regionalization programs significantly decreased maternal and perinatal mortality. …”
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18548
Relative expression of hub genes.
Published 2025“…<p>qPCR results showed that the expression of EXT1 and FMOD was significantly upregulated in DKD mouse(p < 0.01), while SBSPON expression decreased (p < 0.05) and SPTB expression decreased significantly (p < 0.01).…”
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18549
PRMT5 isoforms during zebrafish developmental stages
Published 2024“…NCBI database (version of 2019) was used in the searches. The significance of identification was set to p<0.5, one missed cleavage was allowed, and the expectation value was set to >0.95. …”
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18550
TITAN analyses.
Published 2025“…<p>Taxa significantly associated with increasing or decreasing MAP in our TITAN. …”
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18551
Image 1_The gut microbiome: a vital link to hyperuricemia, gout and acute flares?.pdf
Published 2025“…Furthermore, the gut microbiota of gout patients also exhibited significantly reduced microbial diversity compared with asymptomatic hyperuricemic patients, characterized by decreased richness of the genera Dialister, Ruminococcus, and Faecalibacterium. …”
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18552
Data Sheet 1_Nonlinear responses of ecosystem carbon fluxes to precipitation change in a semiarid grassland.doc
Published 2025“…We found that both decreased and increased precipitation significantly altered the GEP (from –26% to 14%), but only decreased precipitation significantly reduced the ER and NEE (from 1% to 31%), relative to their values during natural precipitation. …”
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18553
Table S13 from Functional Mapping of Epigenomic Regulators Uncovers Coordinated Tumor Suppression by the HBO1 and MLL1 Complexes
Published 2025“…<p>Categories and percent frequency of significantly decreased chromatin accessibility regions</p>…”
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18554
Impacts of winter climate change on northern forest understory carbon dioxide exchange determined by reindeer grazing
Published 2025“…On the contrary, increased snow depth decreased C source strength inside the exclusion offsetting the difference between reindeer grazing treatments. …”
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18555
Data Sheet 1_Effects of nitrogen application amount on nitrogen distribution and photosynthesis in tea leaves.pdf
Published 2025“…Additionally, nitrogen content in the structural system increased slowly, whereas that in the storage system rose significantly. With increasing nitrogen levels, the distribution ratio of leaf nitrogen in the carboxylation and electron transport systems initially increased and then decreased; in the structural system, it first decreased and subsequently stabilized, while in the storage system, it gradually increased. …”
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18556
Table 1_Metabolic changes after growth hormone treatment in children with growth hormone deficiency and small for gestational age: LG observational study.docx
Published 2025“…ALT levels significantly decreased in all follow-up years in the GHD group. …”
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18557
Data Sheet 1_Succinic acid improves crop chemical components by regulating soil chemical properties, microbes and metabolites.docx
Published 2025“…The relative abundance of Proteobacteria in the bacterial community was significantly decreased, while that of Chloroflexi was significantly increased. …”
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18558
<b>Supplementary Fig. 1</b>
Published 2025“…Erlotinib treatment significantly decreased phospho-ERK levels at both concentrations (figure 1, left). …”
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18559
<b>Supplementary Figure 1</b>
Published 2024“…Erlotinib treatment significantly decreased phospho-ERK levels at both concentrations (figure 1, left). …”
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18560
DataSheet1_Dectin-1 participates in the immune-inflammatory response to mouse Aspergillus fumigatus keratitis by modulating macrophage polarization.doc
Published 2024“…The number of macrophages in the corneal stroma of mice in the curdlan pretreatment group increased significantly compared with the PBS group, while in the laminaran pretreatment group this number decreased significantly. 5. …”