Search alternatives:
significantly mediate » significantly mediated (Expand Search), significantly predicted (Expand Search), significantly mitigated (Expand Search)
significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
mediate decrease » mean decrease (Expand Search), mediated defense (Expand Search)
significantly mediate » significantly mediated (Expand Search), significantly predicted (Expand Search), significantly mitigated (Expand Search)
significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
mediate decrease » mean decrease (Expand Search), mediated defense (Expand Search)
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721
Source data for lung metabolomics.
Published 2025“…Our <i>ex vivo</i> inhibition experiment revealed that L-kynurenine, a product of tryptophan metabolism, inhibits T-cell proliferation and induces T-cell apoptosis, further suppressing T-cell mediated responses against bacteria. Importantly, when we knocked out the <i>Ido1</i> gene or inhibited IDO1 expression using a specific inhibitor 1-MT in mice, we observed a significant enhancement in T-cell mediated responses against hv<i>Kp</i>. …”
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722
Source data for Fig 5.
Published 2025“…Our <i>ex vivo</i> inhibition experiment revealed that L-kynurenine, a product of tryptophan metabolism, inhibits T-cell proliferation and induces T-cell apoptosis, further suppressing T-cell mediated responses against bacteria. Importantly, when we knocked out the <i>Ido1</i> gene or inhibited IDO1 expression using a specific inhibitor 1-MT in mice, we observed a significant enhancement in T-cell mediated responses against hv<i>Kp</i>. …”
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723
Source data for Fig 1.
Published 2025“…Our <i>ex vivo</i> inhibition experiment revealed that L-kynurenine, a product of tryptophan metabolism, inhibits T-cell proliferation and induces T-cell apoptosis, further suppressing T-cell mediated responses against bacteria. Importantly, when we knocked out the <i>Ido1</i> gene or inhibited IDO1 expression using a specific inhibitor 1-MT in mice, we observed a significant enhancement in T-cell mediated responses against hv<i>Kp</i>. …”
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724
Flow cytometry gating strategy for MDSC.
Published 2025“…Our <i>ex vivo</i> inhibition experiment revealed that L-kynurenine, a product of tryptophan metabolism, inhibits T-cell proliferation and induces T-cell apoptosis, further suppressing T-cell mediated responses against bacteria. Importantly, when we knocked out the <i>Ido1</i> gene or inhibited IDO1 expression using a specific inhibitor 1-MT in mice, we observed a significant enhancement in T-cell mediated responses against hv<i>Kp</i>. …”
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725
Source data for Fig 3.
Published 2025“…Our <i>ex vivo</i> inhibition experiment revealed that L-kynurenine, a product of tryptophan metabolism, inhibits T-cell proliferation and induces T-cell apoptosis, further suppressing T-cell mediated responses against bacteria. Importantly, when we knocked out the <i>Ido1</i> gene or inhibited IDO1 expression using a specific inhibitor 1-MT in mice, we observed a significant enhancement in T-cell mediated responses against hv<i>Kp</i>. …”
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726
Source data for Fig 4.
Published 2025“…Our <i>ex vivo</i> inhibition experiment revealed that L-kynurenine, a product of tryptophan metabolism, inhibits T-cell proliferation and induces T-cell apoptosis, further suppressing T-cell mediated responses against bacteria. Importantly, when we knocked out the <i>Ido1</i> gene or inhibited IDO1 expression using a specific inhibitor 1-MT in mice, we observed a significant enhancement in T-cell mediated responses against hv<i>Kp</i>. …”
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727
Supplementary file 1_The impact of enterprise digital transformation on employees’ intrinsic motivation: the mediating role of justice perceptions.docx
Published 2025“…The research results, derived from path analysis and moderating effect analysis methods, indicate that enterprise digital transformation has an motivational effect on employees’ intrinsic motivation, and employees’ distributive justice, procedural justice, and interactional justice perceptions all play significant mediating roles, while information processing job characteristics show significantly different moderating effects on different motivational paths: When information processing are low, the distributive justice path loses its motivational effect, while the motivational effect of the interactional justice path significantly decreases when information processing are high, and the moderating effect on the procedural justice path is always insignificant. …”
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728
Image 5_Syzygium aromaticum extract mediated, sustainable silver nanoparticle synergetic with heterocyclic antibiotic clarithromycin and their antimicrobial activities.jpeg
Published 2025“…<p>Microorganisms are becoming resistant to drugs and antimicrobials, making it a significantly critical global issue. Nosocomial infections are resulting in alarmingly increasing rates of morbidity and mortality. …”
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729
Image 2_Syzygium aromaticum extract mediated, sustainable silver nanoparticle synergetic with heterocyclic antibiotic clarithromycin and their antimicrobial activities.jpeg
Published 2025“…<p>Microorganisms are becoming resistant to drugs and antimicrobials, making it a significantly critical global issue. Nosocomial infections are resulting in alarmingly increasing rates of morbidity and mortality. …”
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730
Image 3_Syzygium aromaticum extract mediated, sustainable silver nanoparticle synergetic with heterocyclic antibiotic clarithromycin and their antimicrobial activities.jpeg
Published 2025“…<p>Microorganisms are becoming resistant to drugs and antimicrobials, making it a significantly critical global issue. Nosocomial infections are resulting in alarmingly increasing rates of morbidity and mortality. …”
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731
Image 4_Syzygium aromaticum extract mediated, sustainable silver nanoparticle synergetic with heterocyclic antibiotic clarithromycin and their antimicrobial activities.jpeg
Published 2025“…<p>Microorganisms are becoming resistant to drugs and antimicrobials, making it a significantly critical global issue. Nosocomial infections are resulting in alarmingly increasing rates of morbidity and mortality. …”
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732
Image 6_Syzygium aromaticum extract mediated, sustainable silver nanoparticle synergetic with heterocyclic antibiotic clarithromycin and their antimicrobial activities.jpeg
Published 2025“…<p>Microorganisms are becoming resistant to drugs and antimicrobials, making it a significantly critical global issue. Nosocomial infections are resulting in alarmingly increasing rates of morbidity and mortality. …”
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733
Image 1_Syzygium aromaticum extract mediated, sustainable silver nanoparticle synergetic with heterocyclic antibiotic clarithromycin and their antimicrobial activities.jpeg
Published 2025“…<p>Microorganisms are becoming resistant to drugs and antimicrobials, making it a significantly critical global issue. Nosocomial infections are resulting in alarmingly increasing rates of morbidity and mortality. …”
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734
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735
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736
A study of the mediating role of bedtime music in employment anxiety and sleep quality among college students DATA.xl
Published 2024“…Specifically, β decreased from 0.583 to 0.53, and T decreased from 25.717 to 22.91 Nevertheless, employment anxiety still exhibited a substantial impact on sleep quality (β = 0.53; T = 22.91; P < 0.001).Conclusion: This study concludes that employment-related anxiety has a positive and significant effect on sleep quality. …”
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737
Image1_AMPK Activation Alleviates Myocardial Ischemia-Reperfusion Injury by Regulating Drp1-Mediated Mitochondrial Dynamics.TIF
Published 2024“…The results showed that AICAR, the AMPK activator, could significantly improve the function of left ventricular, decrease arrhythmia incidence and myocardial infarction area of isolated hearts. …”
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738
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739
Hypothetical relationship diagram.
Published 2025“…Three significant indirect pathways were identified: (1) a simple mediation path through emotional exhaustion; (2) a simple mediation path through organizational identification; and (3) a chained mediation path where job insecurity increased emotional exhaustion, which in turn decreased organizational identification, ultimately leading to lower OCB. …”
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740
Path diagram of model.
Published 2025“…Three significant indirect pathways were identified: (1) a simple mediation path through emotional exhaustion; (2) a simple mediation path through organizational identification; and (3) a chained mediation path where job insecurity increased emotional exhaustion, which in turn decreased organizational identification, ultimately leading to lower OCB. …”