Search alternatives:
significantly mediate » significantly mediated (Expand Search), significantly predicted (Expand Search), significantly mitigated (Expand Search)
significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
mediate decrease » mean decrease (Expand Search), mediated defense (Expand Search)
significantly mediate » significantly mediated (Expand Search), significantly predicted (Expand Search), significantly mitigated (Expand Search)
significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
mediate decrease » mean decrease (Expand Search), mediated defense (Expand Search)
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1144
Primers used in RT-qPCR.
Published 2025“…Our data demonstrated that LBH589 effectively suppressed NLRP3 inflammasome activation in lipopolysaccharides (LPS)-primed and adenosine triphosphate (ATP)-stimulated J774A.1 cells and bone marrow-derived macrophages (BMDMs), evidenced by attenuated cleaved caspase-1 and IL-1β, IL-18, IL-16 release, as along with reduced GSDMD-mediated pyroptosis and ASC speck formation. Additionally, LBH589 significantly decreased mitochondrial reactive oxygen species (mtROS) and oxidized mitochondrial DNA (Ox-mtDNA), key triggers of inflammasome activation. …”
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1145
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1146
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1147
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1148
Image 4_Neuropeptide Y neurons in the basolateral amygdala project to the nucleus accumbens and stimulate high-fat intake.jpeg
Published 2025“…The optogenetic inactivation of BLA NPY neurons projecting to the NAc caused a significant decrease in HFD intake for a 1-h period, while optogenetic activation of these neurons induced the opposite effect. …”
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1149
Image 1_Neuropeptide Y neurons in the basolateral amygdala project to the nucleus accumbens and stimulate high-fat intake.jpeg
Published 2025“…The optogenetic inactivation of BLA NPY neurons projecting to the NAc caused a significant decrease in HFD intake for a 1-h period, while optogenetic activation of these neurons induced the opposite effect. …”
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1150
Image 3_Neuropeptide Y neurons in the basolateral amygdala project to the nucleus accumbens and stimulate high-fat intake.jpeg
Published 2025“…The optogenetic inactivation of BLA NPY neurons projecting to the NAc caused a significant decrease in HFD intake for a 1-h period, while optogenetic activation of these neurons induced the opposite effect. …”
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1151
Image 2_Neuropeptide Y neurons in the basolateral amygdala project to the nucleus accumbens and stimulate high-fat intake.jpeg
Published 2025“…The optogenetic inactivation of BLA NPY neurons projecting to the NAc caused a significant decrease in HFD intake for a 1-h period, while optogenetic activation of these neurons induced the opposite effect. …”
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1152
Supplementary file 2_Impact of NF-κB and reactive oxygen species on intracellular BAFF/APRIL expression in ANCA-associated vasculitis: focusing on the effect of resveratrol.docx
Published 2025“…Patients with AAV showed a significant decrease in APRIL expression without significant changes in BAFF expression in CD14+ cells treated with tempol; whereas there was a significant decrease in BAFF and APRIL expression in CD14+ cells treated with SN50. …”
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1153
Supplementary file 1_Impact of NF-κB and reactive oxygen species on intracellular BAFF/APRIL expression in ANCA-associated vasculitis: focusing on the effect of resveratrol.pptx
Published 2025“…Patients with AAV showed a significant decrease in APRIL expression without significant changes in BAFF expression in CD14+ cells treated with tempol; whereas there was a significant decrease in BAFF and APRIL expression in CD14+ cells treated with SN50. …”
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1154
Table 1_Regional high iron deposition is linked with cognitive impairments in peritoneal dialysis: a quantitative susceptibility mapping study.doc
Published 2025“…Every 100 μg/L increase in SF beyond this threshold was associated with a 3.1-point decrease in MoCA score. Iron deposition in the left amygdala showed significant correlations with scores on the Digit Symbol Test (DST), Self-Rating Depression Scale (SDS), Self-Rating Anxiety Scale (SAS), and Verbal Fluency Test (VFT), but exhibited no direct association with peripheral iron metabolism parameters.…”
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1155
Exploring the protective role of DDIT4/mTOR in podocyte integrity through macrophage polarization in diabetic kidney disease
Published 2025“…</p> <p>In the DKD animal model, the expression levels of inflammatory factors in renal tissues were significantly higher than those in the control group. …”
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1156
Data Sheet 1_The small GTPases FoRab5, FoRab7, and FoRab8 regulate vesicle transport to modulate vegetative development and pathogenicity in Fusarium oxysporum f. sp. conglutinans....
Published 2025“…Laccase and glucoamylase activities decreased in a significant manner. Moreover, there was a decrease in the pathogenicity of cabbage seedlings. …”
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1157
Supplementary file 1_Case Report: Loss-of-function TRPM4 mutation p.L91Δ implicated in progressive cardiac conduction defect.docx
Published 2025“…Functional experiments using the patch-clamp approach demonstrated a significant decrease in TRPM4 current, consistent with the biochemical observations.…”
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1158
Table 1_Overall leukocyte levels link risk factors to Von Willebrand factor and Neutrophil Extracellular Traps in stroke thrombi: a Structural Equation Modeling analysis.docx
Published 2025“…</p>Results<p>Heart dysfunction and blood glucose showed a significant negative indirect effect on VWF through the overall leukocyte levels (indirect effect = −0.119 and −0.118, p < 0.05). …”
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1159
Table 1_Preliminary clinical activity of TP-0903 in relapsed or refractory acute myeloid leukemia with FLT3-ITD mutations.docx
Published 2025“…All patients achieved stable disease; however, a significant reduction in bone marrow blast percentage after one to two cycles of treatment was observed in two patients, which correlated with a decrease in FLT3-ITD allelic ratio and variant allele frequency of co-occurring mutations (e.g., NPM1 and DNMT3A). …”
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1160
The P-type calcium pump Spf1 regulates immune response by maintenance of the endoplasmic reticulum-plasma membrane contacts during <i>Candida albicans</i> systemic infection
Published 2024“…Ultimately, the regulatory role of Spf1 in immune response significantly weakened the infectivity of <i>C. albicans</i>, and increased the survival rate of the hosts. …”