Image 1_Tanyu Tongzhi Formula relieves the progression of atherosclerotic plaque through lipid regulation and anti-inflammatory effects.jpeg by Tingting Chen (111216)

“…It decreased the serum levels of lipids and pro-inflammatory mediators (IL-6 and IL-1β) in AS mice. …”

Supplementary Material for: Downregulation of Signal Transducer and Activator of Transcription 4 (STAT4) contributes to impaired osteogenic differentiation of human bone marrow ste... by figshare admin karger (2628495)

“…Unfortunately, hBMSCs rapidly lose their osteogenic differentiation potential during expansion, significantly limiting their applications. Signal transducer and activator of transcription 4 (STAT4) is known to play roles in cell migration, proliferation, and differentiation. …”

Table 1_Effectiveness of Mindfulness and Qigong Training for Self-Healing in patients with Hwabyung and depressive disorder: a randomized controlled trial.docx by Seok-In Yoon (13879160)

“…</p>Results<p>MQT-SH significantly decreased Hwabyung, depression, anxiety, and anger while increasing subjective vitality, and the effectiveness of the intervention were maintained at a short-term follow-up of 6 weeks. …”

Image 1_Effectiveness of Mindfulness and Qigong Training for Self-Healing in patients with Hwabyung and depressive disorder: a randomized controlled trial.tif by Seok-In Yoon (13879160)

“…</p>Results<p>MQT-SH significantly decreased Hwabyung, depression, anxiety, and anger while increasing subjective vitality, and the effectiveness of the intervention were maintained at a short-term follow-up of 6 weeks. …”

Table_1_RETRACTED: miR-335 Targets LRRK2 and Mitigates Inflammation in Parkinson’s Disease.DOCX by Sara R. Oliveira (10972152)

“…Further, miR-335 inhibited LPS-mediated ERK1/2 activation. LRRK2-Wt-induced proinflammatory gene expression was also significantly reduced by miR-335 overexpression. …”

Table 1_Therapeutic potential of Triptolide in inhibiting breast cancer-induced bone destruction – PTHrP as a therapeutic target.docx by Wu Di (11561998)

“…Our findings suggest that TP inhibits NF-κB and ERK signaling pathways, reduces breast cancer-induced osteoclastogenesis, and decreases NFATc1, CTSK, and RANKL expression. Molecular assays revealed a direct binding affinity between TP and PTHrP, suggesting TP interferes with PTHrP‐mediated signaling that promotes osteoclast activity.…”

Supplementary Data for article '<b>Long-term biochar amendment alters microbial necromass carbon accumulation in topsoil and subsoil of two contrasting croplands: Alfisol and Ultis... by Zhiwei Liu (17302867)

“…Compared to the biochar-free control, biochar amendment significantly increased total necromass C (TNC) by 45.9% in the topsoil of Ultisol but decreased it by 9.9% in Alfisol. …”

Deleterious Effects of a GAD65 Monoclonal Autoantibody on Islet Function by Christiane S. Hampe (248347)

“…ISR was suppressed by about 40% after three days of exposure. Mechanisms mediating the effects were found to involve inhibition of mitochondrial generation of ATP, which decreased in parallel with that of ISR. …”

Data Sheet 1_Comprehensive analysis of SQOR involvement in ferroptosis resistance of pancreatic ductal adenocarcinoma in hypoxic environments.zip by Quan Lin (5958)

“…</p>Results<p>PDAC exhibited significantly higher hypoxia levels than normal tissues, correlating with reduced overall survival in patients. …”

Data Sheet 2_Comprehensive analysis of SQOR involvement in ferroptosis resistance of pancreatic ductal adenocarcinoma in hypoxic environments.docx by Quan Lin (5958)

“…</p>Results<p>PDAC exhibited significantly higher hypoxia levels than normal tissues, correlating with reduced overall survival in patients. …”

Data Sheet 1_Epigallocatechin-3-gallate protects against osteoarthritis-induced chondrocytes dysfunction by regulating PLa2g2a.pdf by Mengyuan Dai (9747317)

“…OA model demonstrated that EGCG treatment significantly promoted cartilage repair and increased Pla2g2a expression. …”

Data Sheet 1_Comprehensive analysis of metabolism-related genes in sepsis reveals metabolic–immune heterogeneity and highlights GYG1 as a potential therapeutic target.csv by Jie Zheng (31208)

“…In vivo, Gyg1 was markedly upregulated in septic mice, and LNP-mediated siRNA knockdown of Gyg1 significantly improved survival in the LPS model. …”

Data Sheet 1_Wedelia trilobata-derived biochar mitigates chromium toxicity and improves physiological performance in hydroponically grown Chinese cabbage.docx by Fengyue Qin (21748557)

“…Moreover, calcium and magnesium contents in plant shoots significantly increased by 478.99% and 97.86%, respectively.…”

Table 1_Aerobic exercise ameliorates atherosclerosis-induced cognitive impairment via hippocampal IL-33/NF-κB signaling modulation.xlsx by Jianwei Peng (811819)

“…Furthermore, aerobic exercise reduces M1 microglial activation and pro-inflammatory cytokines like IL-6, TNF-α, and IL-1β in the hippocampus of AS mice, thereby decreasing neuroinflammation. In summary, aerobic exercise can effectively improve cognitive function by decreasing IL-33 expression and inhibiting NF-κB activation, which in turn reduces microglial activation and the release of inflammatory mediators in the hippocampus. …”

Data Sheet 1_Aerobic exercise ameliorates atherosclerosis-induced cognitive impairment via hippocampal IL-33/NF-κB signaling modulation.xlsx by Jianwei Peng (811819)

“…Furthermore, aerobic exercise reduces M1 microglial activation and pro-inflammatory cytokines like IL-6, TNF-α, and IL-1β in the hippocampus of AS mice, thereby decreasing neuroinflammation. In summary, aerobic exercise can effectively improve cognitive function by decreasing IL-33 expression and inhibiting NF-κB activation, which in turn reduces microglial activation and the release of inflammatory mediators in the hippocampus. …”

<b>Litter decomposition regulated by stand ECM dominance but not litter mycorrhizal type in a subtropical mountainous forest</b> by Lu Mengzhen (20146224)

“…</a> AM and ECM litter decomposition in plots with a natural gradient of ECM tree dominance showed that the decomposition rates of both AM litter and ECM litter decreased significantly in plots with increasing ECM dominance. …”

Image 1_Vitamin K protects against lipopolysaccharide-induced intestinal inflammation in piglets by inhibiting the MAPK and PI3K-AKT pathways.pdf by Huakai Wang (505567)

“…</p>Results<p>Morphological analysis revealed that VK significantly restored the decreased villus height and ratio of villus height to crypt depth induced by LPS. …”

Rinderine suppresses African swine fever virus replication in porcine alveolar macrophages by dual targeting of membrane-associated profilin 1 and phosphatidylethanolamine by Di Liu (30843)

“…This study utilized the previously established high-throughput platform for screening ASFV inhibitors to identify rinderine (RIN), a pyrrolizidine alkaloid that not only significantly inhibits ASFV replication but also maintains sustained anti-ASFV activity at 24, 48, and 72 hours postinfection. …”

Deletion of glycosyltransferase <i>galE</i> impairs the InlB anchoring and pathogenicity of <i>Listeria monocytogenes</i> by Xiaowei Fang (696967)

“…Taken together, <i>galE</i> deletion significantly reduced the anchoring of InlB and weakened the pathogenicity of <i>L. monocytogenes</i>. …”

<b>Role of the Chaperone ClpB in</b><b> </b><b>Mycoplasma bovis</b><b> Virulence: Implications for </b><b>stress response, a</b><b>dhesion, </b><b>b</b><b>iofilm </b><b>d</b><b>eve... by Hui zhang (22187170)

“…Phenotypic characterization revealed that ClpB disruption attenuated key virulence attributes, including: impaired host cell adhesion capacity, significant reduction in biofilm formation (p<0.01), diminished induction of proinflammatory cytokines (IL-1β, IL-6, TNF-α) in infected BoMac cells, decreased extracellular nuclease activity. …”