Search alternatives:
significantly mediate » significantly mediated (Expand Search), significantly predicted (Expand Search), significantly mitigated (Expand Search)
significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
mediate decrease » mean decrease (Expand Search), mediated defense (Expand Search)
significantly mediate » significantly mediated (Expand Search), significantly predicted (Expand Search), significantly mitigated (Expand Search)
significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
mediate decrease » mean decrease (Expand Search), mediated defense (Expand Search)
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1701
Data Sheet 2_The impact of sublethal antimicrobial blue light on lipidomic changes of Escherichia coli and Salmonella Typhimurium.csv
Published 2025“…We identified more than 70 lipid species across 6 classes, with over 50% showing significant variations in profile, intensity, and degree of unsaturation following aBL exposure. …”
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1702
Interactive effects of temperature and food ration on growth and mercury concentration in eastern brook trout
Published 2025“…The relative growth rank of individual fish was a significant predictor of Hg concentration, with fast-growing individuals having lower Hg. …”
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1703
Image 1_Yishen-Huoxue formula alleviates renal interstitial fibrosis by attenuating hypoxia-induced renal cell injury and promoting angiogenesis via miR-210/HIF-1α pathway.jpeg
Published 2025“…</p>Results<p>In vivo, YHF treatment significantly attenuated RIF, protected renal function, increased miR-210 expression, and decreased the expression of HIF-1α, BNIP3, and NIX in the serum exosomes of UUO rats. …”
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1704
Supplementary Material for: Alpinia galanga essential oil mitigates gentamycin-induced renal injury: in silico and in vivo studies
Published 2025“…Gal EO significantly decreased Cr, uric acid, BUN, CysC, NGAL and Kim-1 and the urine albumin/creatinine ratio. …”
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1705
Image 2_Yishen-Huoxue formula alleviates renal interstitial fibrosis by attenuating hypoxia-induced renal cell injury and promoting angiogenesis via miR-210/HIF-1α pathway.jpeg
Published 2025“…</p>Results<p>In vivo, YHF treatment significantly attenuated RIF, protected renal function, increased miR-210 expression, and decreased the expression of HIF-1α, BNIP3, and NIX in the serum exosomes of UUO rats. …”
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1706
ZIKV infection enriches the HLA Class I pathway in brain tumour cells.
Published 2025“…Normalised enrichment score (NES) denotes the degree to which the enrichment increased (+) or decreased (-). GSEA analysis significance is defined by p ≤ 0.05 and FDR ≤ 0.25. …”
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1707
Table 1_Elevated miR-17-5p facilitates mycobacterial immune evasion by targeting MAP3K2 in macrophages.doc
Published 2025“…Increased miR-17-5p suppressed MAP3K2 expression and attenuated MAPK signaling, reducing phosphorylation of ERK, JNK, and p38. This resulted in decreased production of inflammatory mediators (TNF-α, IL-6, IL-1β), reduced iNOS and ROS levels, and impaired bacterial clearance.…”
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1708
Table 4_Elevated miR-17-5p facilitates mycobacterial immune evasion by targeting MAP3K2 in macrophages.doc
Published 2025“…Increased miR-17-5p suppressed MAP3K2 expression and attenuated MAPK signaling, reducing phosphorylation of ERK, JNK, and p38. This resulted in decreased production of inflammatory mediators (TNF-α, IL-6, IL-1β), reduced iNOS and ROS levels, and impaired bacterial clearance.…”
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1709
Table 3_Elevated miR-17-5p facilitates mycobacterial immune evasion by targeting MAP3K2 in macrophages.doc
Published 2025“…Increased miR-17-5p suppressed MAP3K2 expression and attenuated MAPK signaling, reducing phosphorylation of ERK, JNK, and p38. This resulted in decreased production of inflammatory mediators (TNF-α, IL-6, IL-1β), reduced iNOS and ROS levels, and impaired bacterial clearance.…”
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1710
Table 2_Elevated miR-17-5p facilitates mycobacterial immune evasion by targeting MAP3K2 in macrophages.doc
Published 2025“…Increased miR-17-5p suppressed MAP3K2 expression and attenuated MAPK signaling, reducing phosphorylation of ERK, JNK, and p38. This resulted in decreased production of inflammatory mediators (TNF-α, IL-6, IL-1β), reduced iNOS and ROS levels, and impaired bacterial clearance.…”
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1711
Data Sheet 1_Biological mechanisms of sodium nitroprusside in enhancing quality of Radix Paeoniae Rubra and Radix Paeoniae Alba.docx
Published 2025“…Moreover, experiments involving combined treatment with SNP and ROS scavengers demonstrated that ROS act as the key mediator linking exogenous NO to the secondary metabolism of P. lactiflora: scavenging ROS significantly attenuated the SNP-induced accumulation of target secondary metabolites.…”
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1712
Image 1_Elevated miR-17-5p facilitates mycobacterial immune evasion by targeting MAP3K2 in macrophages.jpeg
Published 2025“…Increased miR-17-5p suppressed MAP3K2 expression and attenuated MAPK signaling, reducing phosphorylation of ERK, JNK, and p38. This resulted in decreased production of inflammatory mediators (TNF-α, IL-6, IL-1β), reduced iNOS and ROS levels, and impaired bacterial clearance.…”
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1713
Data Sheet 1_A dual inhibitor of TrxR1 and XIAP induces pyroptosis in melanoma.docx
Published 2025“…Mechanistically, TRI-03 not only increases intracellular reactive oxygen species (ROS) levels by inhibiting TrxR1 activity but also decreases XIAP expression, leading to the activation of the caspase-9/caspase-3/GSDME axis and irreversible GSDME-mediated pyroptosis in melanoma cells. …”
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1714
Image 2_Load-bearing aerobic exercise prior to injury moderates systemic immunosuppression response to fracture.jpeg
Published 2025“…Subjects that exercised before fracture had decreased post-fracture circulating immunosuppressive myeloid-derived suppressor cells and pain sensitivity, however there was no significant effect of prehabilitation on bone repair volume, defect bridging rate, or biomechanical properties. …”
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1715
Table 1_Load-bearing aerobic exercise prior to injury moderates systemic immunosuppression response to fracture.docx
Published 2025“…Subjects that exercised before fracture had decreased post-fracture circulating immunosuppressive myeloid-derived suppressor cells and pain sensitivity, however there was no significant effect of prehabilitation on bone repair volume, defect bridging rate, or biomechanical properties. …”
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1716
Table 2_Load-bearing aerobic exercise prior to injury moderates systemic immunosuppression response to fracture.docx
Published 2025“…Subjects that exercised before fracture had decreased post-fracture circulating immunosuppressive myeloid-derived suppressor cells and pain sensitivity, however there was no significant effect of prehabilitation on bone repair volume, defect bridging rate, or biomechanical properties. …”
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1717
Image 1_Load-bearing aerobic exercise prior to injury moderates systemic immunosuppression response to fracture.jpeg
Published 2025“…Subjects that exercised before fracture had decreased post-fracture circulating immunosuppressive myeloid-derived suppressor cells and pain sensitivity, however there was no significant effect of prehabilitation on bone repair volume, defect bridging rate, or biomechanical properties. …”
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1718
Image 4_Unraveling impact and potential mechanisms of baseline pain on efficacy of immunotherapy in lung cancer patients: a retrospective and bioinformatic analysis.jpg
Published 2024“…ELISA assay results indicated that the level of CXCL12 significantly decreased compared to baseline after pain was relieved.…”
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1719
Tilmicosin inhibits the infections of currently prevalent porcine reproductive and respiratory syndrome viruses via the downregulation of CD163 expression
Published 2025“…Flow cytometric analysis indicated that anti-inflammatory may reverse the downregulation effect of tilmicosin on CD163, while pro-inflammatory mediators can enhance the downregulation effect of tilmicosin on CD163, which leads to increased and decreased replication of PRRSV, respectively. …”
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1720
Image_3_Loss of Cdc42 causes abnormal optic cup morphogenesis and microphthalmia in mouse.JPEG
Published 2024“…EdU incorporation is significantly downregulated. In addition, mitotic retinal progenitor cells mislocalize deeper, basal regions, likely contributing to decreased proliferation. …”