Showing 1,881 - 1,900 results of 1,931 for search '(( significant decrease decrease ) OR ( significantly mediate decrease ))~', query time: 0.41s Refine Results
  1. 1881

    Data Sheet 1_Eupalinolide A inhibits cancer progression and induces ferroptosis and apoptosis by targeting the AMPK/mTOR/SCD1 signalling in non-small cell lung cancer.docx by Yonghui Zhang (279832)

    Published 2025
    “…EA treatment (25 mg/kg) markedly inhibited tumour growth in vivo in a xenograft model; both tumour weight and tumour volume decreased by more than 60% without significantly affecting the body weight of tumour-bearing mice.…”
  2. 1882

    Table 1_IP-10 acts early in CV-A16 infection to induce BBB destruction and promote virus entry into the CNS by increasing TNF-α expression.docx by Yajie Hu (550783)

    Published 2024
    “…We observed that the level of IP-10, as well as the TLR3-TRIF-TRAF3-TBK1-NF-κB and RIG-I/MDA5-MAVS-TRAFS-TBK1-NF-κB pathways, which are the upstream of IP-10, were significantly elevated during the course of CV-A16 infection. …”
  3. 1883

    Data Sheet 1_IDO1-AhR axis increases T regulatory cells in Plasmodium vivax malaria infection.pdf by Rafaella Oliveira dos Santos (21710366)

    Published 2025
    “…Introduction<p>Malaria remains a significant public health challenge in Brazil, where Plasmodium vivax (P. vivax) is the predominant species. …”
  4. 1884

    Data Sheet 2_CD44 knockdown alters miRNA expression and their target genes in colon cancer.pdf by Diana Maltseva (11678641)

    Published 2025
    “…Introduction<p>Metastasis formation poses a significant challenge to oncologists, as it severely limits the survival of colorectal cancer (CRC) patients. …”
  5. 1885

    Data Sheet 4_CD44 knockdown alters miRNA expression and their target genes in colon cancer.pdf by Diana Maltseva (11678641)

    Published 2025
    “…Introduction<p>Metastasis formation poses a significant challenge to oncologists, as it severely limits the survival of colorectal cancer (CRC) patients. …”
  6. 1886

    Table 1_LpxR and PagL expression in live attenuated auxotrophic Pseudomonas aeruginosa vaccines modulates lipid A reactogenicity in vitro while preserving immunogenicity.docx by Miriam Moscoso (345679)

    Published 2025
    “…We previously developed a live attenuated auxotrophic vaccine candidate, PAO1 ΔmurI, which conferred protection in murine infection models but exhibited significant reactogenicity when administered intranasally. …”
  7. 1887

    Data Sheet 5_CD44 knockdown alters miRNA expression and their target genes in colon cancer.zip by Diana Maltseva (11678641)

    Published 2025
    “…Introduction<p>Metastasis formation poses a significant challenge to oncologists, as it severely limits the survival of colorectal cancer (CRC) patients. …”
  8. 1888

    Renal Tubule-Specific Angiotensinogen Deletion Attenuates SGLT2 Expression and Ameliorates Diabetic Kidney Disease in Murine Models of Type 1 Diabetes by Wen-Xia Yang (20485041)

    Published 2025
    “…Both Akita RT-<i>Agt</i><sup><em>-/-</em></sup> and STZ-RT-<i>Agt</i><sup><em>-/- </em></sup>mice exhibited significant attenuation of glomerular hyperfiltration, urinary albumin/creatinine ratio, glomerulomegaly and tubular injury</a>. …”
  9. 1889

    Image1_Dexamethasone and IFN-γ primed mesenchymal stem cells conditioned media immunomodulates aberrant NETosis in SLE via PGE2 and IDO.tiff by Khushbu Priya (11863559)

    Published 2024
    “…Background<p>Systemic Lupus Erythematosus (SLE) is characterized by dysregulated immune responses, with neutrophil extracellular traps (NETs) playing a significant role. NETs are recognized by autoantibodies in SLE patients, exacerbating pathology. …”
  10. 1890

    <i>Tmprss6</i> modulates radiation-induced liver injury through the hepcidin axis and PI3K/AKT pathway by Ya-Li Zhou (21696911)

    Published 2025
    “…<p>Radiation-induced liver injury (RILI) poses a significant challenge in abdomino-pelvic tumor radiotherapy, adversely impacting normal liver tissues. …”
  11. 1891

    Data Sheet 1_CD44 knockdown alters miRNA expression and their target genes in colon cancer.pdf by Diana Maltseva (11678641)

    Published 2025
    “…Introduction<p>Metastasis formation poses a significant challenge to oncologists, as it severely limits the survival of colorectal cancer (CRC) patients. …”
  12. 1892

    Image3_Dexamethasone and IFN-γ primed mesenchymal stem cells conditioned media immunomodulates aberrant NETosis in SLE via PGE2 and IDO.tif by Khushbu Priya (11863559)

    Published 2024
    “…Background<p>Systemic Lupus Erythematosus (SLE) is characterized by dysregulated immune responses, with neutrophil extracellular traps (NETs) playing a significant role. NETs are recognized by autoantibodies in SLE patients, exacerbating pathology. …”
  13. 1893

    Image2_Dexamethasone and IFN-γ primed mesenchymal stem cells conditioned media immunomodulates aberrant NETosis in SLE via PGE2 and IDO.tif by Khushbu Priya (11863559)

    Published 2024
    “…Background<p>Systemic Lupus Erythematosus (SLE) is characterized by dysregulated immune responses, with neutrophil extracellular traps (NETs) playing a significant role. NETs are recognized by autoantibodies in SLE patients, exacerbating pathology. …”
  14. 1894

    Data Sheet 3_CD44 knockdown alters miRNA expression and their target genes in colon cancer.pdf by Diana Maltseva (11678641)

    Published 2025
    “…Introduction<p>Metastasis formation poses a significant challenge to oncologists, as it severely limits the survival of colorectal cancer (CRC) patients. …”
  15. 1895

    Data Sheet 2_Effect of thyme-ivy syrup on antiviral immune response in patients with mild COVID-19: a prospective, open-label, randomized pilot study.docx by Stephanie Dauth (13274397)

    Published 2025
    “…On day 7, numerically greater decreases in the thyme-ivy syrup group were observed for some mediators, including IL-10 (−17.7 vs. − 6.0 pg/mL; effect size 0.53) and IL-6 levels (−4.9 vs. − 0.9 pg/mL; effect size 0.87). …”
  16. 1896

    Data Sheet 1_Effect of thyme-ivy syrup on antiviral immune response in patients with mild COVID-19: a prospective, open-label, randomized pilot study.docx by Stephanie Dauth (13274397)

    Published 2025
    “…On day 7, numerically greater decreases in the thyme-ivy syrup group were observed for some mediators, including IL-10 (−17.7 vs. − 6.0 pg/mL; effect size 0.53) and IL-6 levels (−4.9 vs. − 0.9 pg/mL; effect size 0.87). …”
  17. 1897

    Image 2_Standardized aqueous extract of Abutilon theophrasti Medic. ameliorates oxidative stress and inflammatory responses against hydrochloric acid/ethanol-induced gastric ulcer... by Hui Guo (110581)

    Published 2025
    “…In vitro, ATAE treatment significantly lowered nitric oxide (NO) and reactive oxygen species (ROS) production, attenuated nuclear translocation of NF-κB p65, and modulated mRNA expression levels of NF-κB-regulated mediators, including TNF-α, IL-1β, IL-6, MnSOD, GSH-Px, CAT, VCAM-1, and MMP-9. …”
  18. 1898

    Image 1_Standardized aqueous extract of Abutilon theophrasti Medic. ameliorates oxidative stress and inflammatory responses against hydrochloric acid/ethanol-induced gastric ulcer... by Hui Guo (110581)

    Published 2025
    “…In vitro, ATAE treatment significantly lowered nitric oxide (NO) and reactive oxygen species (ROS) production, attenuated nuclear translocation of NF-κB p65, and modulated mRNA expression levels of NF-κB-regulated mediators, including TNF-α, IL-1β, IL-6, MnSOD, GSH-Px, CAT, VCAM-1, and MMP-9. …”
  19. 1899

    Evolutionary tree analysis of ZmSTOMAGEN. by Juan-Juan Xu (18590868)

    Published 2025
    “…<div><p>Stomatal development is mediated by EPIDERMAL PATTERNING FACTORs (EPFs), a family of secreted peptides including STOMAGEN/EPFL9 in <i>Arabidopsis</i>. …”
  20. 1900

    Video 2_Loss of two-pore channel 2 enhances CD8+ T cell cytotoxicity and directly impairs tumour growth via MAPK axis in HCC.mp4 by Lina Ouologuem (22489549)

    Published 2025
    “…Introduction<p>Hepatocellular carcinoma (HCC) remains a major global health challenge, characterised by limited therapeutic options and high mortality rates. Despite significant progress in systemic and immune-based therapies, many patients develop resistance or fail to respond, highlighting the need for new molecular targets. …”