Search alternatives:
significantly mediate » significantly mediated (Expand Search), significantly predicted (Expand Search), significantly mitigated (Expand Search)
significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
mediate decrease » mean decrease (Expand Search), mediated defense (Expand Search)
significantly mediate » significantly mediated (Expand Search), significantly predicted (Expand Search), significantly mitigated (Expand Search)
significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
mediate decrease » mean decrease (Expand Search), mediated defense (Expand Search)
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1881
Data Sheet 1_Eupalinolide A inhibits cancer progression and induces ferroptosis and apoptosis by targeting the AMPK/mTOR/SCD1 signalling in non-small cell lung cancer.docx
Published 2025“…EA treatment (25 mg/kg) markedly inhibited tumour growth in vivo in a xenograft model; both tumour weight and tumour volume decreased by more than 60% without significantly affecting the body weight of tumour-bearing mice.…”
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1882
Table 1_IP-10 acts early in CV-A16 infection to induce BBB destruction and promote virus entry into the CNS by increasing TNF-α expression.docx
Published 2024“…We observed that the level of IP-10, as well as the TLR3-TRIF-TRAF3-TBK1-NF-κB and RIG-I/MDA5-MAVS-TRAFS-TBK1-NF-κB pathways, which are the upstream of IP-10, were significantly elevated during the course of CV-A16 infection. …”
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1883
Data Sheet 1_IDO1-AhR axis increases T regulatory cells in Plasmodium vivax malaria infection.pdf
Published 2025“…Introduction<p>Malaria remains a significant public health challenge in Brazil, where Plasmodium vivax (P. vivax) is the predominant species. …”
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1884
Data Sheet 2_CD44 knockdown alters miRNA expression and their target genes in colon cancer.pdf
Published 2025“…Introduction<p>Metastasis formation poses a significant challenge to oncologists, as it severely limits the survival of colorectal cancer (CRC) patients. …”
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1885
Data Sheet 4_CD44 knockdown alters miRNA expression and their target genes in colon cancer.pdf
Published 2025“…Introduction<p>Metastasis formation poses a significant challenge to oncologists, as it severely limits the survival of colorectal cancer (CRC) patients. …”
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1886
Table 1_LpxR and PagL expression in live attenuated auxotrophic Pseudomonas aeruginosa vaccines modulates lipid A reactogenicity in vitro while preserving immunogenicity.docx
Published 2025“…We previously developed a live attenuated auxotrophic vaccine candidate, PAO1 ΔmurI, which conferred protection in murine infection models but exhibited significant reactogenicity when administered intranasally. …”
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1887
Data Sheet 5_CD44 knockdown alters miRNA expression and their target genes in colon cancer.zip
Published 2025“…Introduction<p>Metastasis formation poses a significant challenge to oncologists, as it severely limits the survival of colorectal cancer (CRC) patients. …”
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1888
Renal Tubule-Specific Angiotensinogen Deletion Attenuates SGLT2 Expression and Ameliorates Diabetic Kidney Disease in Murine Models of Type 1 Diabetes
Published 2025“…Both Akita RT-<i>Agt</i><sup><em>-/-</em></sup> and STZ-RT-<i>Agt</i><sup><em>-/- </em></sup>mice exhibited significant attenuation of glomerular hyperfiltration, urinary albumin/creatinine ratio, glomerulomegaly and tubular injury</a>. …”
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1889
Image1_Dexamethasone and IFN-γ primed mesenchymal stem cells conditioned media immunomodulates aberrant NETosis in SLE via PGE2 and IDO.tiff
Published 2024“…Background<p>Systemic Lupus Erythematosus (SLE) is characterized by dysregulated immune responses, with neutrophil extracellular traps (NETs) playing a significant role. NETs are recognized by autoantibodies in SLE patients, exacerbating pathology. …”
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1890
<i>Tmprss6</i> modulates radiation-induced liver injury through the hepcidin axis and PI3K/AKT pathway
Published 2025“…<p>Radiation-induced liver injury (RILI) poses a significant challenge in abdomino-pelvic tumor radiotherapy, adversely impacting normal liver tissues. …”
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1891
Data Sheet 1_CD44 knockdown alters miRNA expression and their target genes in colon cancer.pdf
Published 2025“…Introduction<p>Metastasis formation poses a significant challenge to oncologists, as it severely limits the survival of colorectal cancer (CRC) patients. …”
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1892
Image3_Dexamethasone and IFN-γ primed mesenchymal stem cells conditioned media immunomodulates aberrant NETosis in SLE via PGE2 and IDO.tif
Published 2024“…Background<p>Systemic Lupus Erythematosus (SLE) is characterized by dysregulated immune responses, with neutrophil extracellular traps (NETs) playing a significant role. NETs are recognized by autoantibodies in SLE patients, exacerbating pathology. …”
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1893
Image2_Dexamethasone and IFN-γ primed mesenchymal stem cells conditioned media immunomodulates aberrant NETosis in SLE via PGE2 and IDO.tif
Published 2024“…Background<p>Systemic Lupus Erythematosus (SLE) is characterized by dysregulated immune responses, with neutrophil extracellular traps (NETs) playing a significant role. NETs are recognized by autoantibodies in SLE patients, exacerbating pathology. …”
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1894
Data Sheet 3_CD44 knockdown alters miRNA expression and their target genes in colon cancer.pdf
Published 2025“…Introduction<p>Metastasis formation poses a significant challenge to oncologists, as it severely limits the survival of colorectal cancer (CRC) patients. …”
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1895
Data Sheet 2_Effect of thyme-ivy syrup on antiviral immune response in patients with mild COVID-19: a prospective, open-label, randomized pilot study.docx
Published 2025“…On day 7, numerically greater decreases in the thyme-ivy syrup group were observed for some mediators, including IL-10 (−17.7 vs. − 6.0 pg/mL; effect size 0.53) and IL-6 levels (−4.9 vs. − 0.9 pg/mL; effect size 0.87). …”
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1896
Data Sheet 1_Effect of thyme-ivy syrup on antiviral immune response in patients with mild COVID-19: a prospective, open-label, randomized pilot study.docx
Published 2025“…On day 7, numerically greater decreases in the thyme-ivy syrup group were observed for some mediators, including IL-10 (−17.7 vs. − 6.0 pg/mL; effect size 0.53) and IL-6 levels (−4.9 vs. − 0.9 pg/mL; effect size 0.87). …”
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1897
Image 2_Standardized aqueous extract of Abutilon theophrasti Medic. ameliorates oxidative stress and inflammatory responses against hydrochloric acid/ethanol-induced gastric ulcer...
Published 2025“…In vitro, ATAE treatment significantly lowered nitric oxide (NO) and reactive oxygen species (ROS) production, attenuated nuclear translocation of NF-κB p65, and modulated mRNA expression levels of NF-κB-regulated mediators, including TNF-α, IL-1β, IL-6, MnSOD, GSH-Px, CAT, VCAM-1, and MMP-9. …”
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1898
Image 1_Standardized aqueous extract of Abutilon theophrasti Medic. ameliorates oxidative stress and inflammatory responses against hydrochloric acid/ethanol-induced gastric ulcer...
Published 2025“…In vitro, ATAE treatment significantly lowered nitric oxide (NO) and reactive oxygen species (ROS) production, attenuated nuclear translocation of NF-κB p65, and modulated mRNA expression levels of NF-κB-regulated mediators, including TNF-α, IL-1β, IL-6, MnSOD, GSH-Px, CAT, VCAM-1, and MMP-9. …”
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1899
Evolutionary tree analysis of ZmSTOMAGEN.
Published 2025“…<div><p>Stomatal development is mediated by EPIDERMAL PATTERNING FACTORs (EPFs), a family of secreted peptides including STOMAGEN/EPFL9 in <i>Arabidopsis</i>. …”
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1900
Video 2_Loss of two-pore channel 2 enhances CD8+ T cell cytotoxicity and directly impairs tumour growth via MAPK axis in HCC.mp4
Published 2025“…Introduction<p>Hepatocellular carcinoma (HCC) remains a major global health challenge, characterised by limited therapeutic options and high mortality rates. Despite significant progress in systemic and immune-based therapies, many patients develop resistance or fail to respond, highlighting the need for new molecular targets. …”