Search alternatives:
significantly mediated » significantly predicted (Expand Search), significantly related (Expand Search), significantly reduced (Expand Search)
significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
mediated decrease » mediated defense (Expand Search), estimated decrease (Expand Search), mediated diseases (Expand Search)
significantly mediated » significantly predicted (Expand Search), significantly related (Expand Search), significantly reduced (Expand Search)
significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
mediated decrease » mediated defense (Expand Search), estimated decrease (Expand Search), mediated diseases (Expand Search)
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Image 1_L1, a 3,3′-diindolylmethane-derivative, induced ER stress-mediated apoptosis and suppressed growth through the FLI1/AKT pathway in erythroleukemia HEL cells.tif
Published 2025“…Recently, our group synthesized and modified a novel DIM derivative, L1, and demonstrated its significant antileukemic activities.</p>Methods<p>MTT assay was used to confirm the inhibition rates and IC<sub>50</sub> value of L1 in erythroleukemia HEL cells. …”
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692
Image 2_L1, a 3,3′-diindolylmethane-derivative, induced ER stress-mediated apoptosis and suppressed growth through the FLI1/AKT pathway in erythroleukemia HEL cells.tif
Published 2025“…Recently, our group synthesized and modified a novel DIM derivative, L1, and demonstrated its significant antileukemic activities.</p>Methods<p>MTT assay was used to confirm the inhibition rates and IC<sub>50</sub> value of L1 in erythroleukemia HEL cells. …”
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693
Table 1_Metabolites mediate the effects of healthy lifestyles on the risks of common age-related diseases.xlsx
Published 2025“…Furthermore, intermediate or healthy lifestyles significantly decreased the age-related risk of stroke, chronic liver disease, chronic kidney disease (CKD), osteoporosis, osteoarthritis, and hypertension. …”
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694
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695
Investigating the Impact of Base Pair Mismatches on Cas13d Cleavage Efficiency Using Molecular Dynamics Simulations
Published 2025“…However, the presence of mismatches significantly undermines the cleavage efficiency of Cas13d to target RNA. …”
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696
Data Sheet 1_Understanding mechanistic relationships between IgG titers and Fc effector functions: a computational framework to assess polyfunctionality.docx
Published 2025“…Surprisingly, simulated boosting of IgG3 alone had the potential to significantly decrease ADCP (p<0.00001), though it would increase ADCC responses. …”
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697
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698
VCC-induced pro-inflammatory responses in DCs are TLR1-dependent but not TLR2-dependent.
Published 2025“…(K) Significant decrease in the IL-6 production in the VCC-treated BMDCs from TLR1<sup>-/-</sup> mice, as compared to those from the wild type (WT) mice. …”
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699
TLR4 is involved in the VCC-induced activation of BMDCs.
Published 2025“…(G-H) Significant decrease in the VCC-mediated IL-6 production in the BMDCs from the C3H/HeJ mice with abrogated TLR4 signalling, compared to that in the BMDCs from the wild type (WT) mice. …”
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700