Search alternatives:
significantly mediated » significantly predicted (Expand Search), significantly related (Expand Search), significantly reduced (Expand Search)
significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
mediated decrease » mediated defense (Expand Search), estimated decrease (Expand Search), mediated diseases (Expand Search)
significantly mediated » significantly predicted (Expand Search), significantly related (Expand Search), significantly reduced (Expand Search)
significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
mediated decrease » mediated defense (Expand Search), estimated decrease (Expand Search), mediated diseases (Expand Search)
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781
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782
Table 1_Microwave ablation triggers OX40L-mediated disruption of TNFRSF4+ Treg immunosuppressive activity.docx
Published 2025“…</p>Results<p>MWA induced three key effects: (1) Phenotypic shift: decreased CTLA-4+ (P<0.0001) Treg subsets, but increased OX40L+ (P<0.01) in LLC cells; (2) Functional impairment: reduced Treg-mediated support for LLC proliferation, migration, and invasion; (3) Enhanced CD8+ T cell cytotoxicity. …”
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783
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784
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785
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786
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787
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788
Data Sheet 2_BNIP3-mediated mitophagy aggravates placental injury in preeclampsia via NLRP1 inflammasome.pdf
Published 2025“…Furthermore, silencing BNIP3 leads to a significant reduction in mitochondrial damage and mtROS production. …”
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789
Data Sheet 1_BNIP3-mediated mitophagy aggravates placental injury in preeclampsia via NLRP1 inflammasome.docx
Published 2025“…Furthermore, silencing BNIP3 leads to a significant reduction in mitochondrial damage and mtROS production. …”
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790
Data Sheet 1_Association of cardiovascular health with COPD (NHANES 2007-2020): mediating potential of lean body mass.docx
Published 2025“…The discrimination ability of lc9 on COPD odds was evaluated using (ROC) curve. Mediation analysis was used to investigate the mediating potential of LBM between lc9 and COPD odds. …”
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791
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792
Table 1_The association between a dietary index for the gut microbiota and frailty in older adults: emphasising the mediating role of inflammatory indicators.docx
Published 2025“…Mediation analysis revealed that inflammatory biomarkers significantly mediated the association between the DI-GM and frailty, with percentages of 16.47% for the neutrophil-to-lymphocyte ratio (NLR), 14.59% for the systemic inflammation response index (SIRI), and 11.13% for the systemic immune-inflammation index (SII). …”
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793
Table 1_GRHL2-HER3 and E-cadherin mediate EGFR-bypass drug resistance in lung cancer cells.xlsx
Published 2025“…GRHL2 was upregulated in ER cells, and its knockdown and knockout significantly reduced erlotinib resistance. Further analysis revealed that GRHL2 upregulates the receptor tyrosine kinase HER3, and that HER3 knockdown similarly decreases the IC<sub>50</sub> for erlotinib. …”
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794
Table 1_The role and impact of the IL-6 mediated JAK2-STAT1/3 signaling pathway in the pathogenesis of gout.xls
Published 2025“…Within the IG group, IL-6, JAK2, STAT3, and IL-1β proteins were significantly elevated compared to the HC group, whereas STAT1, p-JAK2, and p-STAT1/3 proteins were significantly lower. …”
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795
Image 1_The role and impact of the IL-6 mediated JAK2-STAT1/3 signaling pathway in the pathogenesis of gout.jpeg
Published 2025“…Within the IG group, IL-6, JAK2, STAT3, and IL-1β proteins were significantly elevated compared to the HC group, whereas STAT1, p-JAK2, and p-STAT1/3 proteins were significantly lower. …”
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796
Table 1_Association between the dietary index for gut microbiota and metabolic syndrome in adults: the mediating role of body mass index.docx
Published 2025“…Furthermore, BMI played a significant mediating role in the association, accounting for 52.71%.…”
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797
Data Sheet 1_Shengxian decoction alleviates cyclophosphamide-induced immunosuppression via improving B cell-mediated immune responses.docx
Published 2025“…Furthermore, SXD extract significantly inhibits hypoxia and senescence pathways in the spleen.…”
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798
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799
Image2_GABA Type A receptors expressed in triple negative breast cancer cells mediate chloride ion flux.TIF
Published 2024“…Moreover, this GABA<sub>A</sub>R mediated Cl<sup>−</sup> flux can be modulated by pharmacological agents and is decreased in TNBC cells with GABA<sub>A</sub> β3 subunit knockdown. …”
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800
Image1_GABA Type A receptors expressed in triple negative breast cancer cells mediate chloride ion flux.TIF
Published 2024“…Moreover, this GABA<sub>A</sub>R mediated Cl<sup>−</sup> flux can be modulated by pharmacological agents and is decreased in TNBC cells with GABA<sub>A</sub> β3 subunit knockdown. …”