Image 2_Multi-omics analysis reveals neutrophil heterogeneity and key molecular drivers in sepsis-associated acute kidney injury.jpg حسب Tianle Cheng (20788417)

"…We identified four neutrophil subtypes—pro-inflammatory, anti-inflammatory, mature, and immature—revealing a significant increase in pro-inflammatory neutrophils in sepsis (40.53% versus 4.19% in controls) and a decrease in anti-inflammatory neutrophils (18.43% versus 27.04%). …"

Table 1_Preliminary clinical activity of TP-0903 in relapsed or refractory acute myeloid leukemia with FLT3-ITD mutations.docx حسب Bhavana Bhatnagar (11016429)

"…All patients achieved stable disease; however, a significant reduction in bone marrow blast percentage after one to two cycles of treatment was observed in two patients, which correlated with a decrease in FLT3-ITD allelic ratio and variant allele frequency of co-occurring mutations (e.g., NPM1 and DNMT3A). …"

The ADMET analysis of the selected compounds. حسب Ali Alisaac (14658440)

"…<div><p>Quorum sensing (QS) regulates bacterial functions like virulence and biofilm formation, mediated by proteins such as LasI and QscR in <i>Pseudomonas aeruginosa</i>. …"

AMDET profiling parameters and shorting criteria. حسب Ali Alisaac (14658440)

"…<div><p>Quorum sensing (QS) regulates bacterial functions like virulence and biofilm formation, mediated by proteins such as LasI and QscR in <i>Pseudomonas aeruginosa</i>. …"

Dataset: Foraminiferal denitrification and deep bioirrigation influence benthic biogeochemical cycling in a seasonally hypoxic fjord حسب Subhadeep Rakshit (19702714)

"…</p><p dir="ltr">Abstract of the paper: </p><p dir="ltr">Benthic macro- and micro-biota often play significant roles in controlling the biogeochemical dynamics in sediments. …"

MaMsb2, a signaling mucin, is involved in conidiation, stress tolerances, and virulence in the entomopathogenic fungus <i>Metarhizium acridum</i> حسب Hongfen Dai (21975247)

"…Additionally, the <i>MaMsb2</i>-disruption bring about the significantly reduced tolerances to various adversities in <i>M. acridum</i>. …"

Image 1_Heat-not-burn technology affects plasma testosterone levels and markers of inflammation, oxidative stress in the testes of rats.pdf حسب Silvia Granata (2678077)

"…On the other hand, an increase in oxidative stress markers, including those associated with DNA damage, was observed in exposed animals, along with the induction of NF-kB dependent pro-inflammatory mediators: TNF-α, IL-1β, IL-6 and COX-2. Furthermore, inactivation of key androgenic enzymes, such as 3β-hydroxysteroid dehydrogenase and 17β-hydroxysteroid dehydrogenase, together with decreased testosterone synthesis suggest a potential impairment of male gonadal function.…"

Table 1_Manure substitution for chemical nitrogen enhances soil quality without compromising maize yield: a short-term field experiment in Northeast China.xlsx حسب Chao Zhou (471522)

"…Soil microorganisms perform critical functions in mediating soil nutrient cycling after the organic manure application. …"

Table1_Leishmania major surface components and DKK1 signalling via LRP6 promote migration and longevity of neutrophils in the infection site.docx حسب Olivia C. Ihedioha (19925886)

"…Relative to infected BALB/c mice, a significant reduction in parasite load was observed in both LRP6^NKO and LRP6^NKO DKK1^PKO infected mice. …"

Table 1_Overall leukocyte levels link risk factors to Von Willebrand factor and Neutrophil Extracellular Traps in stroke thrombi: a Structural Equation Modeling analysis.docx حسب Lin Shi (65217)

"…</p>Results<p>Heart dysfunction and blood glucose showed a significant negative indirect effect on VWF through the overall leukocyte levels (indirect effect = −0.119 and −0.118, p < 0.05). …"

Table 1_Targeting APE1/Ref-1 to alleviate formalin-induced pain and spinal neuro-inflammation in rats: a promising therapeutic approach.xlsx حسب Eman Elgendy (21811052)

"…Moreover, E3330 administration significantly reduced the expression of key inflammatory mediators including inflammasome markers. …"

Image 3_Chemogenetic modulation of the rat locus coeruleus alters hippocampal noradrenaline release and modulates perforant path-evoked responses.tif حسب Sielke Caestecker (20749481)

"…</p>Results<p>In a significant number of rats (7/15) we found an increase in hippocampal NA release, field excitatory post synaptic potential (fEPSP) slope and population spike (PS) amplitude, indicating an increase in excitatory neurotransmission and neuronal output. 4/15 rats showed a decrease in NA release without changes in fEPSP slope or PS amplitude, and 4/15 showed no change in NA release.…"

Data Sheet 1_Dupilumab treatment has no effect on the nasal microbiome in patients with NSAID-exacerbated respiratory disease: a longitudinal pilot study.pdf حسب Tina Bartosik (12300785)

"…All 8 patients showed significant reduction in TPS (total polyp score; p=0.0078) and an improvement in SNOT-22 (Sino-nasal outcome test-22, a quality of life questionnaire; p=0.0781) after dupilumab therapy. …"

Image 5_Chemogenetic modulation of the rat locus coeruleus alters hippocampal noradrenaline release and modulates perforant path-evoked responses.tif حسب Sielke Caestecker (20749481)

"…</p>Results<p>In a significant number of rats (7/15) we found an increase in hippocampal NA release, field excitatory post synaptic potential (fEPSP) slope and population spike (PS) amplitude, indicating an increase in excitatory neurotransmission and neuronal output. 4/15 rats showed a decrease in NA release without changes in fEPSP slope or PS amplitude, and 4/15 showed no change in NA release.…"

Image 2_Chemogenetic modulation of the rat locus coeruleus alters hippocampal noradrenaline release and modulates perforant path-evoked responses.tif حسب Sielke Caestecker (20749481)

"…</p>Results<p>In a significant number of rats (7/15) we found an increase in hippocampal NA release, field excitatory post synaptic potential (fEPSP) slope and population spike (PS) amplitude, indicating an increase in excitatory neurotransmission and neuronal output. 4/15 rats showed a decrease in NA release without changes in fEPSP slope or PS amplitude, and 4/15 showed no change in NA release.…"

Image 4_Chemogenetic modulation of the rat locus coeruleus alters hippocampal noradrenaline release and modulates perforant path-evoked responses.tif حسب Sielke Caestecker (20749481)

"…</p>Results<p>In a significant number of rats (7/15) we found an increase in hippocampal NA release, field excitatory post synaptic potential (fEPSP) slope and population spike (PS) amplitude, indicating an increase in excitatory neurotransmission and neuronal output. 4/15 rats showed a decrease in NA release without changes in fEPSP slope or PS amplitude, and 4/15 showed no change in NA release.…"

Table 1_Hesperidin alleviates hypothyroidism-related cardiac dysfunction by targeting cardiac miRNAs, Nrf2/NF-κB signaling, oxidative stress and inflammation.docx حسب Asmaa M. Gaber (21640814)

"…</p>Results<p>CMZ intake resulted in a significant decrease in thyroid hormones (THs) levels with a subsequent increase in serum thyroid stimulating hormone and cardiac enzymes activities, dyslipidemia, and body weight gain. …"

Image 1_Chemogenetic modulation of the rat locus coeruleus alters hippocampal noradrenaline release and modulates perforant path-evoked responses.tif حسب Sielke Caestecker (20749481)

"…</p>Results<p>In a significant number of rats (7/15) we found an increase in hippocampal NA release, field excitatory post synaptic potential (fEPSP) slope and population spike (PS) amplitude, indicating an increase in excitatory neurotransmission and neuronal output. 4/15 rats showed a decrease in NA release without changes in fEPSP slope or PS amplitude, and 4/15 showed no change in NA release.…"

Table 1_Chemogenetic modulation of the rat locus coeruleus alters hippocampal noradrenaline release and modulates perforant path-evoked responses.docx حسب Sielke Caestecker (20749481)

"…</p>Results<p>In a significant number of rats (7/15) we found an increase in hippocampal NA release, field excitatory post synaptic potential (fEPSP) slope and population spike (PS) amplitude, indicating an increase in excitatory neurotransmission and neuronal output. 4/15 rats showed a decrease in NA release without changes in fEPSP slope or PS amplitude, and 4/15 showed no change in NA release.…"

Table3_Single-cell RNA sequencing analysis identifies acute changes in the tumor microenvironment induced by interferon α gene therapy in a murine bladder cancer model.csv حسب Alexis R. Steinmetz (18573319)

"…Within the specific cell clusters, IPA analysis revealed significant differences between muAd-Ifnα and control. …"