Table7_Single-cell RNA sequencing analysis identifies acute changes in the tumor microenvironment induced by interferon α gene therapy in a murine bladder cancer model.csv by Alexis R. Steinmetz (18573319)

“…Within the specific cell clusters, IPA analysis revealed significant differences between muAd-Ifnα and control. …”

SEAwise Report on improved predictive models of growth, production and stock quality under different habitat scenarios and incorporating experimental results by Leire Ibaibarriaga (13760979)

“…Summer temperature was not a significant driver of the individual growth. Mediated length-based growth models and linear mixed models applied to weight-at-age data of six stocks showed forecast potential for only one stock (sol.27.20-24). …”

Data Sheet 1_Metabolomics analysis of aqueous humor from patients with high-myopia complicated nuclear cataract.pdf by Qiuyi Huo (21398225)

“…Univariate and multivariate analyses were performed to identify differential metabolites with potential biological significance.</p>Results<p>For HMnC patients, the level of glutathione was decreased, whereas arginine, tyrosine, and tryptophan were more abundant in AH. …”

Data Sheet 2_Metabolomics analysis of aqueous humor from patients with high-myopia complicated nuclear cataract.pdf by Qiuyi Huo (21398225)

“…Univariate and multivariate analyses were performed to identify differential metabolites with potential biological significance.</p>Results<p>For HMnC patients, the level of glutathione was decreased, whereas arginine, tyrosine, and tryptophan were more abundant in AH. …”

Data_Sheet_1_Deregulation of mTORC1-TFEB axis in human iPSC model of GBA1-associated Parkinson’s disease.docx by Fahad Mubariz (16010003)

“…Using PD patients’ induced-pluripotent stem cells (iPSCs), we examined TFEB activity and regulation of the ALP in dopaminergic neuronal cultures generated from iPSC lines harboring heterozygous GBA1 mutations and the CRISPR/Cas9-corrected isogenic controls. Our data showed a significant decrease in TFEB transcriptional activity and attenuated expression of many genes in the CLEAR network in GBA1 mutant neurons, but not in the isogenic gene-corrected cells. …”

Table 1_Inverse association between triglyceride–glucose index and maximal oxygen uptake in US young and middle-aged population: a cross-sectional study.docx by Bin Zhang (64682)

“…</p>Conclusions<p>In the US young and middle-aged population, the TyG index was significantly adversely associated with VO₂max levels. …”

多杀性巴氏杆菌流行过程中水平基因转移对其毒力与耐药的影响-附录.xlsx by He Jiao (19924953)

“…The transcription levels of iron acquisition systems such as fecABCDE, sitABCD operons, and dppAB were also significantly reduced, but the afuAB-dependent periplasmic binding protein-mediated iron transport mechanism was significantly upregulated. …”

<b>Supporting data for ''The pathogenicity and pathogenic mechanism of SARS-CoV-2 Omicron''</b> by Bingjie Hu (10835565)

“…Among the shared spike mutations of BA.1 and BA.2, substitutions S375F and H655Y consistently decrease spike-mediated fusogenicity. Interestingly, the H655Y change consistently reduces serine protease usage while increasing endosomal protease usage. …”

Image 1_Elevated thiamine level is associated with activating interaction between HIF-1α and SLC19A3 in experimental myopic guinea pigs.jpeg by Zhongyu Ma (12275357)

“…</p>Results<p>Compared with the normal control (NC) group, the LIM group guinea pigs showed a significant increase in axial length and decrease in refractive error, as well as a thinning of choroidal thickness and loosening of tissue structure. …”

The MIC values of DDAB for the different strains. by Yuqi Tian (6733070)

“…In an <i>in vivo</i> mice model, the virulence of Δ<i>sugE2</i> and Δ<i>sugE1</i>Δ<i>sugE2</i> mutant strains were enhanced and showed significantly increased bacterial loads in the liver, spleen, and cecum. …”

Data Sheet 1_FOXA2/miR-148a-3p/SMURF2 signaling feed-forward loop alleviates spinal cord ischemia-reperfusion injury-induced neuropathic pain by modulating microglia polarization i... by Xiaotong Hao (20650807)

“…</p>Results<p>SCIRI significantly reduced mechanical and thermal pain thresholds in rats and promoted microglial polarization, with a concomitant decrease in SIRT1 expression and an increase in SMURF2 expression in microglial cells. …”

Data Sheet 2_FOXA2/miR-148a-3p/SMURF2 signaling feed-forward loop alleviates spinal cord ischemia-reperfusion injury-induced neuropathic pain by modulating microglia polarization i... by Xiaotong Hao (20650807)

“…</p>Results<p>SCIRI significantly reduced mechanical and thermal pain thresholds in rats and promoted microglial polarization, with a concomitant decrease in SIRT1 expression and an increase in SMURF2 expression in microglial cells. …”

Data Sheet 1_Shenmai Injection enhances short-term outcomes in ischemic stroke patients after thrombolysis via AMPKα1.docx by Jing Wu (54032)

“…Mechanistic studies revealed that these protective effects were partially mediated through the AMPKα1.</p>Conclusion<p>SMI significantly improves short-term outcomes in IS patients treated with rt-PA thrombolysis. …”

Identification of narciclasine as a novel NRF2 inhibitor by Hoang Hai Ngo (20564072)

“…Finally, we observed that administration of narciclasine significantly decreased the growth of A549 xenografts. …”

Image 3_IL-33 signaling is dispensable for the IL-10-induced enhancement of mast cell responses during food allergy.jpeg by Dylan Krajewski (5881880)

“…To further assess the role of IL-10, food allergy was induced in WT and ST2^-/- mice subjected to antibody-mediated IL-10 depletion. IL-10-depleted WT mice exhibited a significant attenuation in MC-mediated responses to OVA challenge. …”

Image 1_IL-33 signaling is dispensable for the IL-10-induced enhancement of mast cell responses during food allergy.jpeg by Dylan Krajewski (5881880)

“…To further assess the role of IL-10, food allergy was induced in WT and ST2^-/- mice subjected to antibody-mediated IL-10 depletion. IL-10-depleted WT mice exhibited a significant attenuation in MC-mediated responses to OVA challenge. …”

Image 2_IL-33 signaling is dispensable for the IL-10-induced enhancement of mast cell responses during food allergy.jpeg by Dylan Krajewski (5881880)

“…To further assess the role of IL-10, food allergy was induced in WT and ST2^-/- mice subjected to antibody-mediated IL-10 depletion. IL-10-depleted WT mice exhibited a significant attenuation in MC-mediated responses to OVA challenge. …”

Table 1_Specific inhibition of glutamine synthase involved in the metabolic pathway of amino acids is associated with anti-arthritic effects of sinomenine hydrochloride.docx by Gejing Li (18948236)

“…Experimental validation confirmed that SH (50–200 μM) significantly inhibited GS activity and GLUL expression and consequently decreased glutamine levels in RA-FLS. …”

<b>Circular RNA encoding relaxin-2 as a potential therapy for liver fibrosis</b> by jiewen zhong (21472721)

“…In a mouse model of liver fibrosis, the cRLN2 treatment significantly decreased hepatic stellate cell activation and consequently reduced collagen deposition in fibrotic mice, while the treatment by relaxin protein showed limited anti-fibrosis effects. …”

Surface Modification of Islets with L-DOPA-KF7 Enhances Islet Survival by Inhibiting IBMIR in Intrahepatic Islet Transplantation by Daopeng Yang (9701019)

“…Islets coated with L-DOPA-KF7 restored normoglycemia in diabetic mice, and survival time was significantly longer compared to control group. Transplantation of L-DOPA-KF7 coated islets was associated with reduced blood clot formation and decreased infiltration of CD11b+ cells and platelets. …”