Interactive effects of temperature and food ration on growth and mercury concentration in eastern brook trout by Ethan Rutledge (22284511)

“…The relative growth rank of individual fish was a significant predictor of Hg concentration, with fast-growing individuals having lower Hg. …”

An Anti-Inflammatory and Antioxidant Patch Based on Injectable Bioadhesive Hydrogel Prevents Postoperative Atrial Fibrillation by Wei-Qi Lu (445130)

“…In a rat pericarditis model, this localized system significantly reduced atrial inflammation and oxidative stress, promoted anti-inflammatory M2 macrophage polarization, enhanced electrical stability, and markedly decreased POAF susceptibility.…”

An Anti-Inflammatory and Antioxidant Patch Based on Injectable Bioadhesive Hydrogel Prevents Postoperative Atrial Fibrillation by Wei-Qi Lu (445130)

“…In a rat pericarditis model, this localized system significantly reduced atrial inflammation and oxidative stress, promoted anti-inflammatory M2 macrophage polarization, enhanced electrical stability, and markedly decreased POAF susceptibility.…”

The effect of G83R mutation on transthyretin protein structural stability by Xingwang Chen (11225802)

“…In the thermodynamic stability, the quaternary and tertiary structural stability of TTR G83R is lower than wild-type TTR but significantly higher than TTR V30M. The fibril formation rate of TTR G83R under acidic conditions was between that of wild-type TTR and V30M variants. …”

SPEED-ACCURACY TRADE-OFF PARADIGM IN COOPERATIVE TRANSPORT OF ANTS by N FC (19866297)

“…In the scenario with the highest level of simulated competition, we observed a significantly lower percentage of cooperative transport compared to the other scenarios with lower competition. …”

Data_Sheet_1_Role of hypothetical protein PA1-LRP in antibacterial activity of endolysin from a new Pantoea phage PA1.docx by Ye Tian (220278)

“…After 24 h of incubation, the OD₆₀₀ value of pET28a-LRP decreased by 0.164 compared to pET28a. Furthermore, the lytic effect of co-expressed PA1-LRP and PA1-Lys was significantly stronger than each separately. …”

Effect of curcumin on methotrexate-induced ovarian damage and follicle reserve in rats: the role of PARP-1 and P53 by Mete Keçeci (20479508)

“…Expressions of p53 and Poly [ADP-ribose] polymerase 1 (PARP-1) increased significantly in the MTX group compared to the other groups (<i>p</i> < 0,05).…”

Data Sheet 1_Circulating extracellular vesicles and neutrophil extracellular traps contribute to endothelial dysfunction in preeclampsia.pdf by Alex Ramos (16267028)

“…</p>Results<p>VWF, VCAM-1, and ROS expression was significantly higher in cells exposed to PE sera vs. control (12.3 ± 8.1, 3.6 ± 2.3, and 1.8 ± 0.2, respectively, p < 0.05), though significantly lower in cells exposed to depleted PE (dPE) sera (6.1 ± 2.7, 0.7 ± 0.6, and 1.2 ± 0.1, respectively, vs. control, p < 0.05). …”

Data Sheet 1_Comprehensive analysis of SQOR involvement in ferroptosis resistance of pancreatic ductal adenocarcinoma in hypoxic environments.zip by Quan Lin (5958)

“…</p>Results<p>PDAC exhibited significantly higher hypoxia levels than normal tissues, correlating with reduced overall survival in patients. …”

Data Sheet 2_Comprehensive analysis of SQOR involvement in ferroptosis resistance of pancreatic ductal adenocarcinoma in hypoxic environments.docx by Quan Lin (5958)

“…</p>Results<p>PDAC exhibited significantly higher hypoxia levels than normal tissues, correlating with reduced overall survival in patients. …”

Data Sheet 1_A dual inhibitor of TrxR1 and XIAP induces pyroptosis in melanoma.docx by Yuan Wang (14955)

“…Mechanistically, TRI-03 not only increases intracellular reactive oxygen species (ROS) levels by inhibiting TrxR1 activity but also decreases XIAP expression, leading to the activation of the caspase-9/caspase-3/GSDME axis and irreversible GSDME-mediated pyroptosis in melanoma cells. …”

Engineering and Functional Expression of the Type III Secretion System in <i>Xenorhabdus</i>: Enhancing Insecticidal Efficacy and Expanding T3SE Libraries by Xiyin Huang (11528200)

“…In <i>Helicoverpa armigera</i> models, the engineered strain induced severe intestinal damage by suppressing antimicrobial peptide expression and demonstrated improved colonization and biocontrol efficacy (LC₅₀ decreased by 3.7-fold). Crucially, the TT01 derived T3SS mediated delivery of XopAa novel effector exhibiting YopJ-family homology and characteristic T3SS effector featuresinto host cells. …”

Engineering and Functional Expression of the Type III Secretion System in <i>Xenorhabdus</i>: Enhancing Insecticidal Efficacy and Expanding T3SE Libraries by Xiyin Huang (11528200)

“…In <i>Helicoverpa armigera</i> models, the engineered strain induced severe intestinal damage by suppressing antimicrobial peptide expression and demonstrated improved colonization and biocontrol efficacy (LC₅₀ decreased by 3.7-fold). Crucially, the TT01 derived T3SS mediated delivery of XopAa novel effector exhibiting YopJ-family homology and characteristic T3SS effector featuresinto host cells. …”

Engineering and Functional Expression of the Type III Secretion System in <i>Xenorhabdus</i>: Enhancing Insecticidal Efficacy and Expanding T3SE Libraries by Xiyin Huang (11528200)

“…In <i>Helicoverpa armigera</i> models, the engineered strain induced severe intestinal damage by suppressing antimicrobial peptide expression and demonstrated improved colonization and biocontrol efficacy (LC₅₀ decreased by 3.7-fold). Crucially, the TT01 derived T3SS mediated delivery of XopAa novel effector exhibiting YopJ-family homology and characteristic T3SS effector featuresinto host cells. …”

Engineering and Functional Expression of the Type III Secretion System in <i>Xenorhabdus</i>: Enhancing Insecticidal Efficacy and Expanding T3SE Libraries by Xiyin Huang (11528200)

“…In <i>Helicoverpa armigera</i> models, the engineered strain induced severe intestinal damage by suppressing antimicrobial peptide expression and demonstrated improved colonization and biocontrol efficacy (LC₅₀ decreased by 3.7-fold). Crucially, the TT01 derived T3SS mediated delivery of XopAa novel effector exhibiting YopJ-family homology and characteristic T3SS effector featuresinto host cells. …”

Engineering and Functional Expression of the Type III Secretion System in <i>Xenorhabdus</i>: Enhancing Insecticidal Efficacy and Expanding T3SE Libraries by Xiyin Huang (11528200)

“…In <i>Helicoverpa armigera</i> models, the engineered strain induced severe intestinal damage by suppressing antimicrobial peptide expression and demonstrated improved colonization and biocontrol efficacy (LC₅₀ decreased by 3.7-fold). Crucially, the TT01 derived T3SS mediated delivery of XopAa novel effector exhibiting YopJ-family homology and characteristic T3SS effector featuresinto host cells. …”

Table_1_RETRACTED: miR-335 Targets LRRK2 and Mitigates Inflammation in Parkinson’s Disease.DOCX by Sara R. Oliveira (10972152)

“…Further, miR-335 inhibited LPS-mediated ERK1/2 activation. LRRK2-Wt-induced proinflammatory gene expression was also significantly reduced by miR-335 overexpression. …”

Image 1_Therapeutic potential and mechanistic insights of silibinin targeting cancer-associated fibroblasts in colorectal cancer.jpeg by Shenglan He (7641308)

“…Consistently, in vitro experiments demonstrated that SB significantly decreased both protein and mRNA levels of α-SMA and POSTN in fibroblasts (colonic myofibroblast CCD-18Co cell lines.) co-cultured with CRC cell lines (human colorectal adenocarcinoma SW480 and RKO cell lines). …”

Data Sheet 1_Beta-amyloid influences the content and trafficking of beta-amyloid precursor protein via Na,K-ATPase-Src kinase positive feedback loop.pdf by Irina Y. Petrushanko (5696714)

“…Notably, Src kinase inhibition completely blocked the Aβ-induced increase in APP, indicating that beta-amyloid effect on APP is mediated by Src kinase activation. Furthermore, 100 nM CTS ouabain, a specific Na,K-ATPase ligand, significantly decreased Aβ′s impact on APP and Src kinase activation. …”

Image 1_REDD1 attenuates cholestatic liver fibrosis and suppresses PI3K/AKT/mTOR pathway.jpg by Xiaonan Li (340228)

“…</p>Results<p>RNA sequencing revealed REDD1 was significantly upregulated in BDL-induced fibrotic liver tissue. …”