Table 2_The gut commensal Faecalibacterium hominis attenuates indole—AhR signaling and restores ASD—like behaviors with BTBR mice.xlsx by You Yu (2102071)

“…Oral administration of 4P-15 significantly reduced the intestinal levels of indole, indole-3-propionic acid (IPA), and indole-3-acetic acid (IAA), as well as the level of IPA in brain. …”

Table 1_The gut commensal Faecalibacterium hominis attenuates indole—AhR signaling and restores ASD—like behaviors with BTBR mice.xlsx by You Yu (2102071)

“…Oral administration of 4P-15 significantly reduced the intestinal levels of indole, indole-3-propionic acid (IPA), and indole-3-acetic acid (IAA), as well as the level of IPA in brain. …”

Table 2_Deletion of the GntR8 transcriptional regulator impairs Brucella abortus intracellular survival and virulence by modulating stress response genes.docx by Shuwen Li (5058398)

“…The results demonstrate that deletion of gntR8 markedly impairs intracellular survival of B. abortus in RAW264.7 cells and significantly reduces virulence in a mouse infection model. …”

Data Sheet 1_Seaweed (Porphyra) cultivation enhances production of autochthonous refractory dissolved organic matter in coastal ecosystems.docx by Ting Wang (16292)

“…Dissolved organic carbon (DOC) concentration was significantly elevated during the cultivation versus non-cultivation period, while particulate organic carbon (POC) concentration decreased, thereby resulting in a higher DOC/POC ratio in the water column. …”

Table 1_Precipitation-driven restructuring of rhizosphere microbiota enhances alpine plant adaptation.xlsx by Chao Chen (195669)

“…</p>Results<p>Rainfall significantly reduced bacterial alpha diversity, particularly in bulk soils, and triggered a compositional shift from drought-resistant taxa (e.g., Geobacter, Pseudomonas) to moisture-adapted genera (e.g., Azospirillum, Methylobacterium). …”

Table 1_Therapeutic potential of Cervi Cornus Colla in zebrafish bone injury: implications for aquaculture.docx by Fengxia Xu (20175965)

“…In Tg (mpeg1: EGFP) zebrafish, CCC treatment significantly decreased macrophages-associated green fluorescence, suggesting that the extract suppressed the activation of macrophages caused by LPS. …”

Table 1_Deletion of the GntR8 transcriptional regulator impairs Brucella abortus intracellular survival and virulence by modulating stress response genes.xlsx by Shuwen Li (5058398)

“…The results demonstrate that deletion of gntR8 markedly impairs intracellular survival of B. abortus in RAW264.7 cells and significantly reduces virulence in a mouse infection model. …”

Data Sheet 1_Influence of the polysaccharide capsule on virulence and fitness of Klebsiella pneumoniae.pdf by Lisa Zierke (20682053)

“…Infections of Galleria mellonella larvae showed a significantly decreased virulence potential of the CPS-deficient mutant.…”

Disruption of Astrocyte Communication by Carbenoxolone During Shockwave-Induced Stress by Serina Yan (22416354)

“…Peak calcium intensity was significantly reduced at 100 µM CBX, and both rise and fall rates of calcium signals decreased with increasing CBX concentration. …”

Table 1_Therapeutic potential and mechanistic insights of silibinin targeting cancer-associated fibroblasts in colorectal cancer.xlsx by Shenglan He (7641308)

“…Consistently, in vitro experiments demonstrated that SB significantly decreased both protein and mRNA levels of α-SMA and POSTN in fibroblasts (colonic myofibroblast CCD-18Co cell lines.) co-cultured with CRC cell lines (human colorectal adenocarcinoma SW480 and RKO cell lines). …”

Supplementary file 1_The gut commensal Faecalibacterium hominis attenuates indole—AhR signaling and restores ASD—like behaviors with BTBR mice.docx by You Yu (2102071)

“…Oral administration of 4P-15 significantly reduced the intestinal levels of indole, indole-3-propionic acid (IPA), and indole-3-acetic acid (IAA), as well as the level of IPA in brain. …”

Data Sheet 1_Metformin upregulates circadian gene PER2 to inhibit growth and enhance the sensitivity of glioblastoma cell lines to radiotherapy via SIRT2/G6PD pathway.docx by Hailiang Li (740080)

“…Meanwhile, NADPH+ production and G6PDH enzyme activity significantly decreased. Further study validated that metformin inhibited the cell growth of GBM cell lines through up-regulating PER2 and inhibited SIRT2/G6PD signaling pathway, enhancing radiotherapy(RT) sensitivity. …”

Image 2_Endocrine-disrupting effects of environmental BPS and PFOS on human brain organoid development.tiff by Andrea Di Credico (13137135)

“…Importantly, TUNEL assay confirmed the absence of significant cytotoxicity. BPS exposure was associated with reduced ERβ, GPER, and phosphorylated Akt expression, suggesting a possible involvement of estrogen-related pathways. …”

Image 1_Endocrine-disrupting effects of environmental BPS and PFOS on human brain organoid development.tiff by Andrea Di Credico (13137135)

“…Importantly, TUNEL assay confirmed the absence of significant cytotoxicity. BPS exposure was associated with reduced ERβ, GPER, and phosphorylated Akt expression, suggesting a possible involvement of estrogen-related pathways. …”

Data Sheet 3_Identification of telomere-related gene subtypes and prognostic signatures in osteosarcoma.xlsx by Zhaoguang Song (20778602)

“…Finally, we discovered that expression of PDK2, PPARG, MORC4, SP110, TERT and MAP3K5 was significantly decreased in OS cells.</p>Conclusion<p>In conclusion, our study has uncovered the importance of TRGs in defining distinct subtypes of OS with different survival outcomes and immune contexts. …”

Image 1_Identification of telomere-related gene subtypes and prognostic signatures in osteosarcoma.jpeg by Zhaoguang Song (20778602)

“…Finally, we discovered that expression of PDK2, PPARG, MORC4, SP110, TERT and MAP3K5 was significantly decreased in OS cells.</p>Conclusion<p>In conclusion, our study has uncovered the importance of TRGs in defining distinct subtypes of OS with different survival outcomes and immune contexts. …”

Data Sheet 2_Identification of telomere-related gene subtypes and prognostic signatures in osteosarcoma.xlsx by Zhaoguang Song (20778602)

“…Finally, we discovered that expression of PDK2, PPARG, MORC4, SP110, TERT and MAP3K5 was significantly decreased in OS cells.</p>Conclusion<p>In conclusion, our study has uncovered the importance of TRGs in defining distinct subtypes of OS with different survival outcomes and immune contexts. …”

Data Sheet 1_Identification of telomere-related gene subtypes and prognostic signatures in osteosarcoma.xlsx by Zhaoguang Song (20778602)

“…Finally, we discovered that expression of PDK2, PPARG, MORC4, SP110, TERT and MAP3K5 was significantly decreased in OS cells.</p>Conclusion<p>In conclusion, our study has uncovered the importance of TRGs in defining distinct subtypes of OS with different survival outcomes and immune contexts. …”

Data Sheet 1_Integration of hepatic lipidomics and transcriptomics reveals dysregulation of lipid metabolism in a golden hamster model of visceral leishmaniasis.zip by Dongmei Yuan (291583)

“…In the GPL metabolism and AA metabolism pathways, the transcription levels of genes such as phospholipase A2 (PLA2) family enzymes, cyclooxygenase-2 (Cox-2), arachidonate 5-lipoxygenase (Alox5), and hematopoietic prostaglandin D synthase (Hpgds), all of which regulate phospholipid hydrolysis and lipid mediator production, were significantly increased. …”

Data Sheet 1_Epigallocatechin-3-gallate protects against osteoarthritis-induced chondrocytes dysfunction by regulating PLa2g2a.pdf by Mengyuan Dai (9747317)

“…OA model demonstrated that EGCG treatment significantly promoted cartilage repair and increased Pla2g2a expression. …”