Data Sheet 1_Comprehensive analysis of metabolism-related genes in sepsis reveals metabolic–immune heterogeneity and highlights GYG1 as a potential therapeutic target.csv حسب Jie Zheng (31208)

"…In vivo, Gyg1 was markedly upregulated in septic mice, and LNP-mediated siRNA knockdown of Gyg1 significantly improved survival in the LPS model. …"

Data Sheet 1_Wedelia trilobata-derived biochar mitigates chromium toxicity and improves physiological performance in hydroponically grown Chinese cabbage.docx حسب Fengyue Qin (21748557)

"…Moreover, calcium and magnesium contents in plant shoots significantly increased by 478.99% and 97.86%, respectively.…"

ZIKV infection enriches the HLA Class I pathway in brain tumour cells. حسب Matt Sherwood (22530221)

"…Normalised enrichment score (NES) denotes the degree to which the enrichment increased (+) or decreased (-). GSEA analysis significance is defined by p ≤ 0.05 and FDR ≤ 0.25. …"

Table 2_Revealing fitness and virulence determinants of hypervirulent Klebsiella pneumoniae during infection in Galleria mellonella using a transposon library.xlsx حسب Lisheng Xiao (15919517)

"…Going beyond the general knowledge that hypermucoviscosity (HMV) mediates high virulence, we observed that deficits in ptsI and GM2628 led to HMV while decreasing virulence. …"

Anthropogenic CO2–induced seawater acidification driven the biogeochemical processes of dimethylsulfide in Northwestern Pacific marginal seas حسب Xuxu Gao (9724883)

"…Seawater acidification exerts significant control over marine biogeochemical cycles, including those involving of dimethylsulfide (DMS), a critical climate-regulating sulfur compound. …"

Table 1_Revealing fitness and virulence determinants of hypervirulent Klebsiella pneumoniae during infection in Galleria mellonella using a transposon library.xlsx حسب Lisheng Xiao (15919517)

"…Going beyond the general knowledge that hypermucoviscosity (HMV) mediates high virulence, we observed that deficits in ptsI and GM2628 led to HMV while decreasing virulence. …"

Table 1_Overcoming tet(X)-harboring tigecycline resistance: a study on the efficacy of tigecycline-apramycin combinations.docx حسب Juan Liu (6492)

"…Introduction<p>The emergence of the wide variety of novel tigecycline resistance tet(X) variants, including tet(X3), tet(X4), tet(X5), and tet(X6), has raised a serious threat to global public health and posed a significant challenge to the clinical treatment of multidrug-resistant bacterial infections.…"

Data Sheet 1_Revealing fitness and virulence determinants of hypervirulent Klebsiella pneumoniae during infection in Galleria mellonella using a transposon library.pdf حسب Lisheng Xiao (15919517)

"…Going beyond the general knowledge that hypermucoviscosity (HMV) mediates high virulence, we observed that deficits in ptsI and GM2628 led to HMV while decreasing virulence. …"

Supplemental file for Training alters cytokine and soluble receptor responses حسب Jeremy Ducharme (20174820)

"…Following 1-hour of cycling at their respiratory compensation point, untrained men (n=5) exhibited a significant increase in pro-inflammatory cytokines, including IL-6, TNF-α, IL-1β, CCL2, and VEGFA. …"

Image 4_Unraveling impact and potential mechanisms of baseline pain on efficacy of immunotherapy in lung cancer patients: a retrospective and bioinformatic analysis.jpg حسب Zexin Zhang (7507979)

"…ELISA assay results indicated that the level of CXCL12 significantly decreased compared to baseline after pain was relieved.…"

Image_3_Loss of Cdc42 causes abnormal optic cup morphogenesis and microphthalmia in mouse.JPEG حسب Katrina S. Hofstetter (17545425)

"…EdU incorporation is significantly downregulated. In addition, mitotic retinal progenitor cells mislocalize deeper, basal regions, likely contributing to decreased proliferation. …"

Data Sheet 1_Anti-colorectal cancer effect of total minor ginsenosides produced by lactobacilli transformation of major ginsenosides by inducing apoptosis and regulating gut microb... حسب Yunjiao Shen (20524133)

"…</p>Results<p>In vitro studies demonstrated that TMG significantly inhibited proliferation and promoted apoptosis in CT26.WT cells. …"

Image 2_Unraveling impact and potential mechanisms of baseline pain on efficacy of immunotherapy in lung cancer patients: a retrospective and bioinformatic analysis.jpg حسب Zexin Zhang (7507979)

"…ELISA assay results indicated that the level of CXCL12 significantly decreased compared to baseline after pain was relieved.…"

Image 1_Unraveling impact and potential mechanisms of baseline pain on efficacy of immunotherapy in lung cancer patients: a retrospective and bioinformatic analysis.jpg حسب Zexin Zhang (7507979)

"…ELISA assay results indicated that the level of CXCL12 significantly decreased compared to baseline after pain was relieved.…"

Image_2_Loss of Cdc42 causes abnormal optic cup morphogenesis and microphthalmia in mouse.jpg حسب Katrina S. Hofstetter (17545425)

"…EdU incorporation is significantly downregulated. In addition, mitotic retinal progenitor cells mislocalize deeper, basal regions, likely contributing to decreased proliferation. …"

Table 1_Statins regulate kinase signaling by causing changes in phosphorylation, rather than through changes in gene expression or direct inhibition: evidence in colorectal cancer.... حسب Francisco Alejandro Lagunas-Rangel (13849122)

"…Affected kinases were significantly enriched in cancer-associated pathways, including insulin signaling, EGF–EGFR signaling, PI3K/AKT signaling, and the PD-L1/PD-1 immune checkpoint axis. …"

Image_2_Loss of Cdc42 causes abnormal optic cup morphogenesis and microphthalmia in mouse.jpg حسب Katrina S. Hofstetter (17545425)

"…EdU incorporation is significantly downregulated. In addition, mitotic retinal progenitor cells mislocalize deeper, basal regions, likely contributing to decreased proliferation. …"

Image_3_Loss of Cdc42 causes abnormal optic cup morphogenesis and microphthalmia in mouse.JPEG حسب Katrina S. Hofstetter (17545425)

"…EdU incorporation is significantly downregulated. In addition, mitotic retinal progenitor cells mislocalize deeper, basal regions, likely contributing to decreased proliferation. …"

Table 1_WTAP modulates macrophage polarization in rheumatoid arthritis by targeting exosomal circ-CBLB via m6A modification.docx حسب Dawei Yan (193244)

"…</p>Results<p>In the enhanced inflammatory microenvironment of RA, circ-CBLB expression was observed to be significantly downregulated. Further functional validation showed that inhibition of exosome secretion intensified macrophage polarization toward the pro-inflammatory M1 phenotype. …"

Table 1_ADAM8 in macrophages exacerbates sepsis-induced cardiomyopathy by impeding efferocytosis.docx حسب Zhenjun Ji (11050644)

"…</p>Results<p>Here, we demonstrate that ADAM8 expression is significantly upregulated in cardiac macrophages of SICM mice using single-cell transcriptomics and immunofluorescence. …"