SEAwise synthetic summary report of the findings of WP4 on changes to the ecosystem impacts of fishing in response to spatial management for online tool by Anna Rindorf (6217391)

“…While the attainment of GES could also be found in scenarios with closed areas, this was generally restricted to the indicators at which the closure was aimed while other indicators worsened.</p><p dir="ltr">Decreasing fishing effort to levels compatible with FMSY-min resulted in slightly but not significantly higher average landings in the Adriatic and western Ionian Sea and the North Sea under current climate where currently overfished gadoid stocks were rebuilt in the simulations. …”

Lingganwuweijiangxin Decoction suppresses allergic airway inflammation in Guinea pigs with cough variant asthma by regulating the treg/Th17 balance and the JAK1/STAT6 signaling pat... by Yu Lai (764498)

“…</p> <p>Compared to the control group, the model group showed significantly more coughs, which were markedly reduced by LD treatment (<i>p</i> = 0.0083 and <i>p</i> = 0.0117). …”

Table 1_Associations between gut microbiota and diet composition of three arid-adapted rodent species from the Inner Mongolia grassland.doc by Muha Cha (4002941)

“…In contrast, the consumption of animal-based foods significantly decreased microbial diversity. This finding suggests a potential link between the host’s genetic background, dietary composition, and the gut microbiota.…”

3-D surface plot showing the interactive effect of ultrasonic frequency (kHz) and the variation ratio of DES and water on the TPC of Sabah snake grass extract. by Tong Yen Suan (21656185)

“…Similarly, TPC increases more significantly at lower water content, highlighting the critical role of solvent composition in facilitating solute-solvent interactions and enhancing extraction kinetics. …”

Therapeutic Administration Success Rates. by Alani Mohanad Khalid Ahmed (22693496)

“…One-Way ANOVA with statistical significance at p < 0.05 (*p < 0.05, **p < 0.01, and ***p < 0.001).…”

Table 1_MIND diet score and its association with metabolic dysfunction-associated steatotic liver disease and gut microbiota profiles: a cross-sectional study.docx by Shengbo Yang (295144)

“…Inflammatory markers (CRP, LPS) decreased with higher adherence (all p < 0.001). Each 1-unit increase in MIND diet score was significantly associated with reductions in fasting insulin (β = −0.20 μU/mL; p < 0.001), HOMA-IR (β = −2.11; p < 0.001), CRP (β = −2.12; p < 0.001), LPS (β = −8.52; p < 0.001). …”

Data Sheet 1_BAM8-22 targets spinal MrgC receptors to modulate UPRmt activity in the mechanism of bone cancer pain.docx by Mingming Xie (20963636)

“…Background<p>Bone cancer pain (BCP) significantly impacts patients’ overall quality of life. …”

Table 1_A population database analysis to describe the residual burden of varicella in Italy—a high vaccination coverage area—from 2004 to 2022.docx by Elisa Barbieri (115023)

“…In the Veneto Region, following the implementation of VV in 2006, the IR significantly decreased by 20.5 annually (95% CI: −23.4, −17.5), ranging from 50.2 per 1,000 person-years in 2006 to 1.2 per 1,000 person-years in 2022.…”

Table 3_Epidemiology of neonatal disorders attributable to low birthweight-global burden of disease research, 1990–2021.xlsx by Qi Zhang (28502)

“…</p>Conclusion<p>Over the past 32 years, the global burden of neonatal diseases attributable to LBW has significantly decreased, but inequality in disease burden has intensified. …”

Mapping global urban inequality under climate change and its interaction with sustainable development by Yinshuai Li (20382495)

“…<p>Global cities are significantly affected by climate change, leading to increased inequality and further vulnerability among marginalized groups. …”

Image 1_The role of E2F1 in promoting EIF4EBP1 transcription in cryptorchid mice: association with autophagy in germ cells.tif by Jianguo Zhang (6482)

“…E2F1 was identified as an upstream regulator of EIF4EBP1, with knockdown of E2F1 significantly decreasing EIF4EBP1 promoter activity and binding. …”

<b>Differences in White Matter Microstructure in Children With Type 1 Diabetes Persist During Longitudinal Follow up: Relation to Dysglycemia</b> by Nelly Mauras (8103110)

“…</p><p dir="ltr">We observed in 182 children (121 type 1 diabetes, vs. 61 controls) who had testing at Time 4 that FA increased, and RD, AD, MD decreased significantly in both groups, with no differences between groups for FA, RD and MD over time. …”

Table_2_Receptor Tyrosine Kinase Inhibitor Sunitinib as Novel Immunotherapy to Inhibit Myeloid-Derived Suppressor Cells for Treatment of Endometriosis.xls by Ying He (125930)

“…We found that Sunitinib significantly decreased the endometriotic lesion size and weight after 1 and 3 weeks, and decreased p-STAT3 activation in MDSCs after 1 week of treatment. …”

Table 1_Gypenoside XLIX inhibiting PI3K/AKT/FOXO1 signaling pathway mediated neuronal mitochondrial autophagy to improve patients with ischemic stroke.docx by Yonglei Liu (5485793)

“…</p>Results<p>Gypenoside XLIX significantly improved neuronal viability (p < 0.01), reduced apoptosis (p < 0.01), and decreased ROS levels (p < 0.001) in OGD cells. …”

Table_3_Receptor Tyrosine Kinase Inhibitor Sunitinib as Novel Immunotherapy to Inhibit Myeloid-Derived Suppressor Cells for Treatment of Endometriosis.xls by Ying He (125930)

“…We found that Sunitinib significantly decreased the endometriotic lesion size and weight after 1 and 3 weeks, and decreased p-STAT3 activation in MDSCs after 1 week of treatment. …”

Table 1_Anemoside B4 targets RAGE to attenuate ferroptosis in sepsis-induced acute lung injury.xlsx by Yue Bu (11357379)

“…</p>Results<p>AB4 ameliorated CLP-induced lung injury in mice, as evidenced by reduced pathological damage, lower injury scores, and a decreased lung wet-to-dry weight ratio. In vivo, AB4 significantly reduced levels of pro-inflammatory cytokines (IL-1β, TNF-α, and IL-6), decreased oxidative stress markers MDA and DHE, and increased GSH levels. …”

Table 2_Anemoside B4 targets RAGE to attenuate ferroptosis in sepsis-induced acute lung injury.xlsx by Yue Bu (11357379)

“…</p>Results<p>AB4 ameliorated CLP-induced lung injury in mice, as evidenced by reduced pathological damage, lower injury scores, and a decreased lung wet-to-dry weight ratio. In vivo, AB4 significantly reduced levels of pro-inflammatory cytokines (IL-1β, TNF-α, and IL-6), decreased oxidative stress markers MDA and DHE, and increased GSH levels. …”

Data Sheet 1_Global, regional, and national trends and burden of multiple sclerosis in adolescents and young adults: a data analysis from 1990 to 2021 and projections to 2040.zip by Peixi Zhao (620068)

“…Background and Objectives<p>Multiple sclerosis (MS) significantly impacts adolescents and young adults (aged 15–39 years), causing substantial neurological disability. …”

Table 2_MIND diet score and its association with metabolic dysfunction-associated steatotic liver disease and gut microbiota profiles: a cross-sectional study.docx by Shengbo Yang (295144)

“…Inflammatory markers (CRP, LPS) decreased with higher adherence (all p < 0.001). Each 1-unit increase in MIND diet score was significantly associated with reductions in fasting insulin (β = −0.20 μU/mL; p < 0.001), HOMA-IR (β = −2.11; p < 0.001), CRP (β = −2.12; p < 0.001), LPS (β = −8.52; p < 0.001). …”

Data Sheet 2_Global, regional, and national trends and burden of multiple sclerosis in adolescents and young adults: a data analysis from 1990 to 2021 and projections to 2040.docx by Peixi Zhao (620068)

“…Background and Objectives<p>Multiple sclerosis (MS) significantly impacts adolescents and young adults (aged 15–39 years), causing substantial neurological disability. …”