Table2_Overexpression of endothelial S1pr2 promotes blood–brain barrier disruption via JNK/c-Jun/MMP-9 pathway after traumatic brain injury in both in vivo and in vitro models.DOCX... by Hongbo Cheng (2848235)

“…</p>Results<p>The expression of S1pr2 significantly increased following TBI in mice. Pharmacological inhibition of S1pr2 alleviated secondary injury with reduced lesion volume, ROS generation, cerebral oedema, neurological deficits, and neuronal apoptosis; BBB disruption was also mitigated, accompanied by reduced degradation of tight junction proteins and decreased induction of matrix metalloproteinases-9 (MMP-9) post-TBI. …”

Table3_Overexpression of endothelial S1pr2 promotes blood–brain barrier disruption via JNK/c-Jun/MMP-9 pathway after traumatic brain injury in both in vivo and in vitro models.DOCX... by Hongbo Cheng (2848235)

“…</p>Results<p>The expression of S1pr2 significantly increased following TBI in mice. Pharmacological inhibition of S1pr2 alleviated secondary injury with reduced lesion volume, ROS generation, cerebral oedema, neurological deficits, and neuronal apoptosis; BBB disruption was also mitigated, accompanied by reduced degradation of tight junction proteins and decreased induction of matrix metalloproteinases-9 (MMP-9) post-TBI. …”

Table 4_Tackling global inequalities in maternal hypertensive disorders: trends and the impact of public health emergencies, 1990–2021.xlsx by Siying Wei (5990276)

“…Disease burden generally decreased with higher SDI levels. Decomposition analysis suggested that demographic factors increased the burden, while epidemiology mitigated it. …”

Image 3_Assessment of the brain impact of soccer heading using pupillary light reflex.tif by Junzo Nakao (21429026)

“…In session 2, only CH significantly decreased compared with the baseline. CH significantly decreases from the 20th heading onwards in session 1 compared with session 2 (both at 20 and 30 headings; p < 0.001). …”

Table 1_Assessment of the brain impact of soccer heading using pupillary light reflex.docx by Junzo Nakao (21429026)

“…In session 2, only CH significantly decreased compared with the baseline. CH significantly decreases from the 20th heading onwards in session 1 compared with session 2 (both at 20 and 30 headings; p < 0.001). …”

Image 2_Assessment of the brain impact of soccer heading using pupillary light reflex.tif by Junzo Nakao (21429026)

“…In session 2, only CH significantly decreased compared with the baseline. CH significantly decreases from the 20th heading onwards in session 1 compared with session 2 (both at 20 and 30 headings; p < 0.001). …”

Image 1_Assessment of the brain impact of soccer heading using pupillary light reflex.tif by Junzo Nakao (21429026)

“…In session 2, only CH significantly decreased compared with the baseline. CH significantly decreases from the 20th heading onwards in session 1 compared with session 2 (both at 20 and 30 headings; p < 0.001). …”

Image 4_Assessment of the brain impact of soccer heading using pupillary light reflex.tif by Junzo Nakao (21429026)

“…In session 2, only CH significantly decreased compared with the baseline. CH significantly decreases from the 20th heading onwards in session 1 compared with session 2 (both at 20 and 30 headings; p < 0.001). …”

Modulation of cardiovascular function by rooibos in adults at risk for cardiovascular disease by Maria Diana Hartnick (7007012)

“…The LA / AO ratio did not change significantly in all the intervention groups. Interventricular septum diameter (IVSd) in the placebo group decreased significantly (p=0.002) from 1.33 cm ± 0.030 cm to 1.25 cm ± 0.03 cm with no positive change in the fermented rooibos group, while the green rooibos group demonstrated a significantly (p=0.002) decreased diameter from 1.28 cm ± 0.04 cm to 1.19 cm ± 0.03 cm. …”

SEAwise report on the impact of socio-economic effects of fisheries management by Isabella Bitetto (20145735)

“…Depending on the specific fleet and country, the results indicated that management measures positioned between the extremes of status quo and FMSY with a strict enforcement of the landing obligation can potentially mitigate some of the negative socioeconomic impacts of climate change on the fishery and decrease CO₂ emissions per kg of fish landed. …”

Data Sheet 2_Co-administration of vitamin D and N-acetylcysteine to modulate immunosenescence in older adults with vitamin D deficiency: a randomized clinical trial.pdf by Samira Rastgoo (15252703)

“…</p>Results<p>After the intervention, supplementation with D5N and D5 significantly downregulated p16, interleukin-6 (IL-6), and tumor necrosis factor-α (TNF-α) expression and decreased SA-β-gal activity compared to the D1 group. …”

Data Sheet 1_Co-administration of vitamin D and N-acetylcysteine to modulate immunosenescence in older adults with vitamin D deficiency: a randomized clinical trial.pdf by Samira Rastgoo (15252703)

“…</p>Results<p>After the intervention, supplementation with D5N and D5 significantly downregulated p16, interleukin-6 (IL-6), and tumor necrosis factor-α (TNF-α) expression and decreased SA-β-gal activity compared to the D1 group. …”

Data Sheet 1_Irrigation, variety, and year exert a greater influence on organic potato production than microbial inoculation: case study results of a 2-year on-farm experiment.docx by Orsolya Papp (18206269)

“…Concerning the effects of microbial inoculations, significant differences were observed only in plant stomatal conductance among all measured parameters: inoculation with T. asperelloides significantly decreased stomatal conductance in potato plants. …”

Supporting data for “Androgen receptor modulates chemotherapy response in breast cancer” by Chanping You (9067448)

“…Chromatin immunoprecipitation (ChIP) sequencing identified 1,209 AR-regulated genes, with gene ontology (GO) analysis highlighting significant enrichment of ubiquitin-related genes. qPCR validation pinpointed TRIM37, an AR-regulated E3 ligase, as a mediator of RB1 degradation. …”

Table 2_Downsizing chronic disease management programs for type 2 diabetes patients during the COVID-19 pandemic: changes in healthcare utilization patterns.docx by Corinne Rijpkema (12587274)

“…In Q1 of 2020, type 2 diabetes patient visits to out-of-hours GP services rose notably, but decreased in Q1 of 2021, compared to 2019. Hospital care for diabetes showed a significant increase in Q2 of 2021 (+11.3%), compared to Q2 2019 and regular GP care increased from Q1 2021 (up to +11.1% in Q3 2021). …”

Table 1_Downsizing chronic disease management programs for type 2 diabetes patients during the COVID-19 pandemic: changes in healthcare utilization patterns.docx by Corinne Rijpkema (12587274)

“…In Q1 of 2020, type 2 diabetes patient visits to out-of-hours GP services rose notably, but decreased in Q1 of 2021, compared to 2019. Hospital care for diabetes showed a significant increase in Q2 of 2021 (+11.3%), compared to Q2 2019 and regular GP care increased from Q1 2021 (up to +11.1% in Q3 2021). …”

Data Sheet 1_Exogenous putrescine modulates variety-specific cadmium tolerance in wheat seedlings: synergistic roles of antioxidant defense and physiological homeostasis.pdf by Dandan Zhong (388523)

“…Introduction<p>Cadmium (Cd) contamination in farmland is a significant environmental issues affecting crop yields. …”

Data Sheet 1_Alternate wetting and drying irrigation at tillering stage enhances the heat tolerance of rice by increasing sucrose and cytokinin content in panicles.docx by Ti Gao (21442307)

“…Here, to investigate the alleviating effect of AWD on heat damage to rice (Oryza sativa L.), we selected four rice varieties with different high-temperature resistance (Liangyoupeijiu, IR64, Huanghuazhan, Shanyou 63), two irrigation treatments at the tillering stage including AWD and continuous flooding (CF) and two temperature treatments at the PI stage (high daytime temperature, HDT; and control temperature, CK) were applied. HDT significantly reduced the yield of all four varieties except for Shanyou 63, primarily by decreasing the spikelet fertility and spikelet number, while AWD significantly improved the two traits under HDT. …”

Data (F. Ghasemian).sav by Mona Rahnavardi (21220424)

“…The re-</p><p dir="ltr">sults of the multiple linear regression analysis also showed that with an increase in the total score of</p><p dir="ltr">maternal lifestyles, the antenatal anxiety score decreases significantly after controlling the Demo-</p><p dir="ltr">graphic and obstetrics variable. …”

Efficacy of lifting devices for wheelchair transfers: a systematic review and meta-analysis by Nur Shuhaidatul Sarmiza Abdul Halim (12487875)

“…Motorised lifting devices significantly decreased biomechanical stress among nurses [SMD −0.68; 95% CI −1.02 to −0.34], whereas non-motorised counterparts showed no significant change [SMD − 0.23; 95% CI −0.59 to 0.13]. …”