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significantly mitigated » significantly mediated (Expand Search), significantly elevated (Expand Search), significantly related (Expand Search)
significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
mitigated decrease » estimated decrease (Expand Search)
significantly mitigated » significantly mediated (Expand Search), significantly elevated (Expand Search), significantly related (Expand Search)
significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
mitigated decrease » estimated decrease (Expand Search)
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1021
Data Sheet 1_Baicalein ameliorates DSS-induced ulcerative colitis in mice by inhibiting ferroptosis and regulating gut microbiota.docx
Published 2025“…After baicalein treatment, the proinflammatory cytokines (TNF-α, IL-1β), and anti-inflammatory cytokine (IL-10) has decreased. Additionally, high-dose of baicalein strongly reversed oxidative stress alterations caused by DSS, as evidenced by Fe<sup>2+</sup>, MDA, ROS significantly depleted, and MPO, SOD, GSH significantly increased. …”
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1022
Data Sheet 1_Antiviral therapy can effectively suppress irAEs in HBV positive hepatocellular carcinoma treated with ICIs: validation based on multi machine learning.zip
Published 2025“…Effective control of viral load through antiviral therapy significantly mitigates the occurrence of irAEs.</p>Conclusion<p>ICIs show therapeutic potential in the treatment of HBV-HCC. …”
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1023
Complete dataset of loon productivity for Fuirst et al.
Published 2025“…While all regions showed long-term mean productivity rates at or above the threshold considered necessary for population stability (0.48 chicks fledged per territorial pair), we found significant declines in productivity (-0.17− -2.8% per year over 19−48 years) in seven regions, non-significant but downward trends in four others, and a non-significant increase in one region (Maine). …”
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1024
Data Sheet 1_The role of lycopene in alleviating soybean meal-induced intestinal injury in an early-weaned piglet model.docx
Published 2025“…</p>Conclusion<p>These findings demonstrated that lycopene supplementation in SBM-based diets significantly enhanced antioxidant capacity, decreased apoptosis in small intestinal cells, improved intestinal barrier function and morphology, and optimized gut microbiota composition. …”
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1025
Data Sheet 1_Assessing the efficacy and safety of pentoxifylline in preventing chemotherapy-induced peripheral neuropathy and mucositis in breast cancer patients.pdf
Published 2025“…</p>Conclusion<p>The co-administration of PTX with AC/T chemotherapy in breast cancer patients significantly decreases the incidence and postpones the onset of grade 2 or higher peripheral neuropathy and the incidence of mucositis without causing additional risks for the patients.…”
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1026
Data Sheet 1_Patient engagement in radiation oncology: a large retrospective study of survey response dynamics.docx
Published 2025“…MVA showed that higher socioeconomic disadvantage significantly decreased survey participation (ADI third tertile vs. first tertile OR=0.708, p<0.001), with each unit increase in ADI reducing the odds of completion by 1% (p<0.001). …”
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1027
Data Sheet 1_Metabolic modulation and multi-species interaction: Lactiplantibacillus plantarum’s impact on Streptococcus mutans-Candida albicans in a mucosal model.pdf
Published 2025“…Notably, L. plantarum significantly altered the metabolic landscape of these pathogens, especially under GOS conditions.…”
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1028
LncRNA MCM3AP-AS1 protects against cerebral ischemia-reperfusion injury via targeting miR-27b-3p
Published 2025“…<p>Cerebral ischemia-reperfusion (CI/R) injury is a significant hurdle in ischemic stroke treatment. Substantial evidence indicates that long non-coding RNAs (lncRNAs) are implicated in CI/R injury. …”
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1029
Data Sheet 1_Integrated physiological, transcriptomic, and metabolomic analyses of Chrysanthemum ‘Boju’ under excessive indole-3-acetic acid stress.pdf
Published 2025“…Exogenous IAA treatment also led to a significant reduction in endogenous hormone levels, including gibberellins (GA<sub>3</sub> and GA<sub>4</sub>), abscisic acid (ABA), and IAA, with decreases of 93%, 45%, 99%, and 99%, respectively.Transcriptomic and metabolomic analyses identified 263 differentially expressed metabolites and 144 differentially expressed genes.…”
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1030
Supplementary file 1_Global burden of HIV, syphilis, and HBV infection among women of childbearing age and children under five: based on the Global Burden of Diseases Study 2021.do...
Published 2025“…</p>Conclusion<p>In 2021, the global disease burden of HIV, syphilis, and HBV infection remained high among WCBA and children under five, with significant regional and demographic disparities. These findings indicate a persistent public health challenge, necessitating continued global efforts to mitigate the burden through addressing socioeconomic inequalities, strengthening health education, and expanding healthcare access.…”
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1031
The efficacy of metformin in counteracting olanzapine-induced hyperprolactinemia: an open-label prospective study
Published 2025“…</p> <p>After eight weeks of metformin intervention, prolactin levels significantly decreased from 39.7 ± 20.0 ng/mL at baseline to 35.7 ± 15.7 ng/mL (<i>p</i> = 0.005) with a moderate effect size (Cohen’s <i>d</i> = 0.545). …”
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1032
DataSheet1_Morphological, physiological, and biochemical responses of three different soybean (Glycine max L.) varieties under salinity stress conditions.docx
Published 2024“…The concentrations of chlorophyll a and b decreased with increasing salinity. In addition, salinity significantly increased leaf electrolyte leakage (EL), lipid peroxidation, proline accumulation, and phenol and flavonoid content. …”
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1033
Image 6_Burden of pulmonary arterial hypertension in children globally, regionally, and nationally (1990–2021): results from the global burden of disease study.tif
Published 2025“…</p>Results<p>The findings indicate a stable prevalence rate globally, with a slight increase in the absolute number of cases. Significantly, reductions were observed in both mortality and disability-adjusted life years (DALYs) associated with pediatric PAH, with mortality decreasing by 57.66% and DALYs by 63.59% over the study period, indicating progress in mitigating the disease burden. …”
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1034
Image 3_Burden of pulmonary arterial hypertension in children globally, regionally, and nationally (1990–2021): results from the global burden of disease study.tif
Published 2025“…</p>Results<p>The findings indicate a stable prevalence rate globally, with a slight increase in the absolute number of cases. Significantly, reductions were observed in both mortality and disability-adjusted life years (DALYs) associated with pediatric PAH, with mortality decreasing by 57.66% and DALYs by 63.59% over the study period, indicating progress in mitigating the disease burden. …”
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1035
Data Sheet 1_Cardiovascular outcomes in adult patients with atrial septal defect: a nationwide population-based study.docx
Published 2025“…Additionally, a beneficial effect on coronary revascularization was observed in the surgery group, whereas the impact on MI was not significantly different between the groups. ASD closure, whether by surgery or using a device, is associated with a decreased incidence of cardiovascular outcomes in adults. …”
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1036
Image 1_Burden of pulmonary arterial hypertension in children globally, regionally, and nationally (1990–2021): results from the global burden of disease study.tif
Published 2025“…</p>Results<p>The findings indicate a stable prevalence rate globally, with a slight increase in the absolute number of cases. Significantly, reductions were observed in both mortality and disability-adjusted life years (DALYs) associated with pediatric PAH, with mortality decreasing by 57.66% and DALYs by 63.59% over the study period, indicating progress in mitigating the disease burden. …”
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1037
Table 2_Burden of pulmonary arterial hypertension in children globally, regionally, and nationally (1990–2021): results from the global burden of disease study.docx
Published 2025“…</p>Results<p>The findings indicate a stable prevalence rate globally, with a slight increase in the absolute number of cases. Significantly, reductions were observed in both mortality and disability-adjusted life years (DALYs) associated with pediatric PAH, with mortality decreasing by 57.66% and DALYs by 63.59% over the study period, indicating progress in mitigating the disease burden. …”
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1038
Table 1_Mowing of Carex brevicuspis (Cyperaceae) improves food quality for herbivorous geese in Dongting Lake: the potential mechanisms.xlsx
Published 2025“…However, mowing treatments also significantly decreased plant height, density, aboveground biomass, and the biomass of belowground bud banks, which potentially impairs the long-term recovery and sustainability of plant. …”
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1039
Table 4_Burden of pulmonary arterial hypertension in children globally, regionally, and nationally (1990–2021): results from the global burden of disease study.docx
Published 2025“…</p>Results<p>The findings indicate a stable prevalence rate globally, with a slight increase in the absolute number of cases. Significantly, reductions were observed in both mortality and disability-adjusted life years (DALYs) associated with pediatric PAH, with mortality decreasing by 57.66% and DALYs by 63.59% over the study period, indicating progress in mitigating the disease burden. …”
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1040
Table 3_Burden of pulmonary arterial hypertension in children globally, regionally, and nationally (1990–2021): results from the global burden of disease study.docx
Published 2025“…</p>Results<p>The findings indicate a stable prevalence rate globally, with a slight increase in the absolute number of cases. Significantly, reductions were observed in both mortality and disability-adjusted life years (DALYs) associated with pediatric PAH, with mortality decreasing by 57.66% and DALYs by 63.59% over the study period, indicating progress in mitigating the disease burden. …”