بدائل البحث:
significantly mitigated » significantly mediated (توسيع البحث), significantly elevated (توسيع البحث), significantly related (توسيع البحث)
significant decrease » significant increase (توسيع البحث), significantly increased (توسيع البحث)
mitigated decrease » estimated decrease (توسيع البحث)
significantly mitigated » significantly mediated (توسيع البحث), significantly elevated (توسيع البحث), significantly related (توسيع البحث)
significant decrease » significant increase (توسيع البحث), significantly increased (توسيع البحث)
mitigated decrease » estimated decrease (توسيع البحث)
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1301
Table 1_Resveratrol targeting MDM2/P53/PUMA axis to inhibit colonocyte apoptosis in DSS-induced ulcerative colitis mice.xlsx
منشور في 2025"…</p>Results<p>Resveratrol treatment effectively repaired colonic damage in the UC mouse model by significantly increasing colon length, reducing inflammatory cell infiltration, and mitigating mucosal injury. …"
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1302
Implementation and clinical impact of an interdisciplinary tool to promote skin integrity after flap surgery in Veterans with spinal cord injury
منشور في 2024"…This paper describes the development and implementation of the Minneapolis Spinal Cord Optimization, Rehabilitation and Empowerment (SCORE), a preoperative interdisciplinary tool for risk assessment and mitigation, and reports its effect on the one-year flap failure rate (significant breakdown).…"
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1303
Table 1_Global burden of pneumoconiosis from 1990 to 2021: a comprehensive analysis of incidence, mortality, and socio-demographic inequalities in 204 countries and territories.doc...
منشور في 2025"…These rates were generally elevated in low-income and lower-middle-income regions, where males exhibited significantly higher ASIR and ASDR compared to females. …"
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1304
Supplementary Material for: DOT1L regulates cellular senescence during the progression from acute kidney injury to chronic kidney disease via the micro-222-5p/WNT9B signaling pathw...
منشور في 2025"…Results: The results demonstrated that in vivo inhibition of DOT1L significantly reduced cellular senescence and improved renal tubular injury and interstitial fibrosis. …"
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1305
Table_1_Clinical pharmacist interventions in nutrition-and drug-related problems in critically ill patients with renal dysfunction: a non-randomized controlled study.DOCX
منشور في 2024"…Their collaboration with healthcare professionals significantly reduced both DRPs and NRPs.</p>…"
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1306
<b>Combination of isobavachalcone and amphotericin B has antifungal effect against </b><b>Cryptococcus neoformans</b><b>and protects host tissue damage by inhibiting ferroptosis</b...
منشور في 2025"…The results demonstrated that IBC (4 μg/mL) significantly reduced the minimum inhibitory concentration (MIC) of AmB from 1 μg/mL to 0.25 μg/mL, indicating a fourfold increase in potency. …"
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1307
Data Sheet 1_PitNET tissue deconvolution: tracing normal tissue residues and immune dynamics.pdf
منشور في 2025"…However, its limited ability to resolve cellular heterogeneity – particularly in samples containing residual non-tumor pituitary cells – remains a significant challenge.</p>Objective<p>We developed and validated a tissue deconvolution framework using a reference dataset derived from single-nucleus RNA sequencing (snRNA-seq) of normal pituitary tissue, aimed at estimating cellular composition in PitNETs from bulk RNA-seq data and characterizing the tumor microenvironment (TME).…"
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1308
Dexmedetomidine improves septic acute kidney injury by inhibiting inflammation and oxidative stress through the activation of the Pink1/Park2 autophagy pathway
منشور في 2025"…Notably, all results were statistically significant. Overall, our findings revealed that dexmedetomidine may mitigate inflammation, oxidative stress, and renal dysfunction in mice with SAKI by upregulating the Pink1/Park2-mediated autophagy pathway. …"
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1309
Data Sheet 1_Cannabinoid receptor 2 selective agonist ameliorates adjuvant-induced arthritis by modulating the balance between Treg and Th17 cells.docx
منشور في 2025"…</p>Conclusion<p>HU-308 demonstrates significant anti-inflammatory effects in AIA by restoring Th17/Treg balance and reducing joint damage. …"
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1310
Data Sheet 2_PitNET tissue deconvolution: tracing normal tissue residues and immune dynamics.pdf
منشور في 2025"…However, its limited ability to resolve cellular heterogeneity – particularly in samples containing residual non-tumor pituitary cells – remains a significant challenge.</p>Objective<p>We developed and validated a tissue deconvolution framework using a reference dataset derived from single-nucleus RNA sequencing (snRNA-seq) of normal pituitary tissue, aimed at estimating cellular composition in PitNETs from bulk RNA-seq data and characterizing the tumor microenvironment (TME).…"
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1311
Table 2_PitNET tissue deconvolution: tracing normal tissue residues and immune dynamics.xlsx
منشور في 2025"…However, its limited ability to resolve cellular heterogeneity – particularly in samples containing residual non-tumor pituitary cells – remains a significant challenge.</p>Objective<p>We developed and validated a tissue deconvolution framework using a reference dataset derived from single-nucleus RNA sequencing (snRNA-seq) of normal pituitary tissue, aimed at estimating cellular composition in PitNETs from bulk RNA-seq data and characterizing the tumor microenvironment (TME).…"
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1312
Table 1_PitNET tissue deconvolution: tracing normal tissue residues and immune dynamics.xlsx
منشور في 2025"…However, its limited ability to resolve cellular heterogeneity – particularly in samples containing residual non-tumor pituitary cells – remains a significant challenge.</p>Objective<p>We developed and validated a tissue deconvolution framework using a reference dataset derived from single-nucleus RNA sequencing (snRNA-seq) of normal pituitary tissue, aimed at estimating cellular composition in PitNETs from bulk RNA-seq data and characterizing the tumor microenvironment (TME).…"
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1313
Table 1_Singing for memory: neural and cognitive effects of a choral intervention in older adults.docx
منشور في 2025"…</p>Results<p>Partial correlation analyses, adjusting for age and cognitive ability, showed significant improvements in episodic memory following both the control period (T1-T2) and the choir intervention (T2-T3), but only the latter scaled with rehearsal attendance. …"
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1314
Table_1_Effect of diet low in omega-6 polyunsaturated fatty acids on the global burden of cardiovascular diseases and future trends: evidence from the Global Burden of Disease 2021...
منشور في 2025"…The most significant effects were seen in individuals aged 75 and older, with a higher disease burden noted in males. …"
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1315
Data Sheet 1_Self-esteem and peer pressure susceptibility mediating the link between maternal behavior and adolescent risk behaviors.pdf
منشور في 2025"…Although parental influence decreases and peer influence increases during this time, parental behavior still plays a significant role. …"
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1316
Table 3_PitNET tissue deconvolution: tracing normal tissue residues and immune dynamics.xlsx
منشور في 2025"…However, its limited ability to resolve cellular heterogeneity – particularly in samples containing residual non-tumor pituitary cells – remains a significant challenge.</p>Objective<p>We developed and validated a tissue deconvolution framework using a reference dataset derived from single-nucleus RNA sequencing (snRNA-seq) of normal pituitary tissue, aimed at estimating cellular composition in PitNETs from bulk RNA-seq data and characterizing the tumor microenvironment (TME).…"
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1317
Data Sheet 1_Quantifying the temporal trends of the combined effect of temperature and relative humidity on hand, foot, and mouth disease in Yunnan, China.pdf
منشور في 2025"…Background<p>Hand, foot, and mouth disease (HFMD) poses a significant risk to children. While most studies focus on the individual effects of temperature or relative humidity, the combined effect of these factors and their temporal variations remain unclear. …"
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1318
Maresin-1 alleviates sepsis-induced acute kidney injury by inhibiting ferroptosis via the Nrf2/HO-1/Gpx4 signaling pathway
منشور في 2025"…Nrf2 knockdown was used to validate its role in MaR-1-mediated effects.</p> <p>MaR-1 significantly improved cell viability and reduced ferroptosis-related markers (ROS, MDA, and iron ion concentration) <i>in vitro</i>. …"
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1319
Image 1_Prevention of chemotherapy drug-mediated human hair follicle damage: combined use of cooling with antioxidant suppresses oxidative stress and prevents matrix keratinocyte c...
منشور في 2025"…Scalp cooling remains the only available method to mitigate CIA, but its effectiveness varies amongst patients. …"
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1320
Table 1_Jing-Yin-Gu-Biao formula protects mice from postinfluenza Staphylococcus aureus infection by ameliorating acute lung injury and improving hypercoagulable state via inhibiti...
منشور في 2025"…</p>Results<p>The administration of JYGBF significantly ameliorated acute lung injury (ALI) and inhibited overactivated inflammatory response (MIP-2, IL-6, etc.) in mice with postinfluenza S. aureus infection. …"