Table 4_Unveiling the immunological landscape of disseminated tuberculosis: a single-cell transcriptome perspective.xlsx by Zhen Gong (292434)

“…</p>Results<p>Our analysis revealed a significantly higher proportion of inflammatory immune cells (e.g., monocytes and macrophages) in DTB patients, along with a notably lower abundance of various lymphocytes (including T cells, B cells, and plasma cells), suggesting that lymphopenia is a prominent feature of the disease. …”

Data Sheet 1_The association between the gut microbiome and antituberculosis drug-induced liver injury.docx by Shengfei Pei (20852069)

“…</p>Results<p>Following anti-TB treatment, we observed a decrease in microbial diversity and significant structural changes in the gut microbiota of TB patients (P < 0.05). …”

Pediatric CPP with Praat and ADSV (Joshi et al., 2025) by Ashwini Joshi (21594817)

“…Age and <i>F</i>0 are significant predictors of CPP; however, the observed increase in CPP with increasing age in males is primarily due to the substantial decrease in <i>F</i>0 postpuberty. …”

Data Sheet 1_Analysis of serum amino acids and tryptophan metabolites to predict hepatic encephalopathy in portal hypertension patients receiving a transjugular intrahepatic portal... by Li Bao (323211)

“…</p>Results<p>We quantitatively determined 20 serum amino acids, and found that 4 amino acid levels were increased significantly in patients who complicated HE after TIPS. …”

Supplemental information to: Female mice with HSD17B1 inactivation show mild hyperandrogenism without notable impact on reproductive function or bone by Arttu Junnila (22503041)

“…Our results demonstrate that the blockade of HSD17B1-dependent E2 synthesis is successfully compensated for in mouse<i> in vivo</i>, resulting in only a mild ovarian estrogen and androgen imbalance, but no significant adverse effects on reproductive or bone health.…”

Table 1_Linking the Planetary Health Diet Index to sarcopenia: the mediating effect of the non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio (N... by Huan Chen (6545)

“…Analysis of the dose–response curve suggested a linear relationship between PHDI and sarcopenia. Furthermore, a significant positive association was identified between NHHR and sarcopenia [OR = 1.09, 95% CI: 1.03, 1.16], with NHHR found to decrease as PHDI increased [beta coefficient (β) = −0.09, 95% CI: −0.11, −0.06]. …”

Supplementary file 1_Analysis of gender- and age-stratified asthma burden: forecasting prevalence trends in 2030.docx by Zhenzhen Pan (2637463)

“…In China, smoking emerged as a significant risk factor for men, while the risk associated with high body mass index (BMI) has increased notably in recent years. …”

Data Sheet 1_Effects of continuous cropping on soil metabolomics and rhizosphere bacterial communities in Panax quinquefolius L..docx by Jian Song (4232)

“…Microbial community composition was assessed using Illumina high-throughput sequencing, and metabolite profiles were analyzed using non-targeted metabolomics (UPLC-MS/MS).</p>Results<p>Significant decreases were observed in soil pH (12.2–28.0%), cation exchange capacity (42.6–65.5%), organic matter (8.7–27.3%), total nitrogen (7.6–27.8%), and ammonium (NH₄⁺) content (16.9–56.6%) with an increasing number of continuous cropping years. …”

Data Sheet 2_Effects of continuous cropping on soil metabolomics and rhizosphere bacterial communities in Panax quinquefolius L..docx by Jian Song (4232)

“…Microbial community composition was assessed using Illumina high-throughput sequencing, and metabolite profiles were analyzed using non-targeted metabolomics (UPLC-MS/MS).</p>Results<p>Significant decreases were observed in soil pH (12.2–28.0%), cation exchange capacity (42.6–65.5%), organic matter (8.7–27.3%), total nitrogen (7.6–27.8%), and ammonium (NH₄⁺) content (16.9–56.6%) with an increasing number of continuous cropping years. …”

Table 1_Quantifying the effect of air pollution and temperature on hospitalization costs for chronic lower respiratory diseases.docx by Huanhuan Jia (2546878)

“…</p>Conclusion<p>A significant association was observed between increased air pollutant concentrations and the hospitalization costs of patients with CLRDs, with heterogeneity among different populations. …”

Data Sheet 1_The walking surface influences vertical ground reaction force and centre of pressure data obtained with pressure-sensing insoles.pdf by Elke Warmerdam (13895493)

“…VGRF and COP data were significantly influenced by the type of surface. The rmANOVA revealed significant within-subject differences between the walking surfaces in all calculated parameters. …”

Image 4_Safety and efficacy of PD-1 inhibitors plus tyrosine kinase inhibitors combination therapy in patients with advanced hepatocellular carcinoma combined with hyperbilirubinem... by Shida Pan (12696593)

“…Multifactorial analysis showed that MELD score >18 and increased total bilirubin (TBIL) levels within one week were significant risk factors for OS. Patients with a decrease in TBIL levels within one week had significantly prolonged median OS (not reached vs 3.3months, P =0.013) and median PFS (7.03 months vs 2.77 months, P =0.010).…”

Data from: The efficacy of inactivated vaccine against H5 clade 2.3.4.4b highly pathogenic avian influenza virus in turkeys by Erica Spackman (17362552)

“…There was 100% survival in all groups except the sham exposure group which had 100% mortality. A significant decrease in viral shedding was observed in all exposed groups compared to the shams, although the 9wk group shed significantly higher quantities by the cloacal route at seven days post challenge (DPC) compared to the 3wk group. …”

Image 2_Safety and efficacy of PD-1 inhibitors plus tyrosine kinase inhibitors combination therapy in patients with advanced hepatocellular carcinoma combined with hyperbilirubinem... by Shida Pan (12696593)

“…Multifactorial analysis showed that MELD score >18 and increased total bilirubin (TBIL) levels within one week were significant risk factors for OS. Patients with a decrease in TBIL levels within one week had significantly prolonged median OS (not reached vs 3.3months, P =0.013) and median PFS (7.03 months vs 2.77 months, P =0.010).…”

Data_Sheet_1_Global burden of drug use disorders by region and country, 1990–2021.docx by Shuyan Zhang (426593)

“…Nationally, the United States of America reported the largest increase in age-standardized DALY rates and EAPC for ASIR (EAPC of 4.88, 1.05, respectively), while South Africa had the most significant decrease in EAPC (EAPC of −3.62, −1.52, respectively). …”

Table 1_Safety and efficacy of PD-1 inhibitors plus tyrosine kinase inhibitors combination therapy in patients with advanced hepatocellular carcinoma combined with hyperbilirubinem... by Shida Pan (12696593)

“…Multifactorial analysis showed that MELD score >18 and increased total bilirubin (TBIL) levels within one week were significant risk factors for OS. Patients with a decrease in TBIL levels within one week had significantly prolonged median OS (not reached vs 3.3months, P =0.013) and median PFS (7.03 months vs 2.77 months, P =0.010).…”

DataSheet1_Enhancing human islet xenotransplant survival and function in diabetic immunocompetent mice through LRH-1/NR5A2 pharmacological activation.pdf by N. Cobo-Vuilleumier (14625173)

“…Accordingly, in mice treated with BL001 for 8 weeks, the beta cell mass was preserved, while a significant decrease in alpha cells was observed compared to mice treated with BL001 for only 4 weeks. …”

Supplementary Material for: Effects of a Sugar-Sweetened Beverages Tax on Caries in Italy: a Modelling Study. by figshare admin karger (2628495)

“…Significant benefits were observed in Southern Italy, an area with higher caries rates and lower dental care utilization, where the impact was pronounced in both scenarios. …”

Supplementary Material for: Phase angle as an indicator of depression in maintenance hemodialysis patients by Li X. (3218241)

“…Median PhA level (interquartile range, IQR) of depressed patients was 4.4° (3.9-4.9°) for males and 3.9° (3.2-4.7°) for females. There was a significant decrease in the prevalence of depression with increasing quartiles of PhA levels. …”

Table_2_Global burden of drug use disorders by region and country, 1990–2021.docx by Shuyan Zhang (426593)

“…Nationally, the United States of America reported the largest increase in age-standardized DALY rates and EAPC for ASIR (EAPC of 4.88, 1.05, respectively), while South Africa had the most significant decrease in EAPC (EAPC of −3.62, −1.52, respectively). …”