Image 3_Safety and efficacy of PD-1 inhibitors plus tyrosine kinase inhibitors combination therapy in patients with advanced hepatocellular carcinoma combined with hyperbilirubinem... by Shida Pan (12696593)

“…Multifactorial analysis showed that MELD score >18 and increased total bilirubin (TBIL) levels within one week were significant risk factors for OS. Patients with a decrease in TBIL levels within one week had significantly prolonged median OS (not reached vs 3.3months, P =0.013) and median PFS (7.03 months vs 2.77 months, P =0.010).…”

Image 1_Safety and efficacy of PD-1 inhibitors plus tyrosine kinase inhibitors combination therapy in patients with advanced hepatocellular carcinoma combined with hyperbilirubinem... by Shida Pan (12696593)

“…Multifactorial analysis showed that MELD score >18 and increased total bilirubin (TBIL) levels within one week were significant risk factors for OS. Patients with a decrease in TBIL levels within one week had significantly prolonged median OS (not reached vs 3.3months, P =0.013) and median PFS (7.03 months vs 2.77 months, P =0.010).…”

Supplementary Material for: Patients with Opioid Use Disorder Choosing Treatment with Extended-Release Naltrexone: A 6-Months Naturalistic Study by Brenna I.H. (19773549)

“…The majority of the MITT population (84; 60.9%) completed 24 weeks of treatment in the study. There was a significant decrease in the overall use of opioids (p<0.001) and the use of alcohol and other illicit substances was low. …”

Table_1_Global burden of drug use disorders by region and country, 1990–2021.docx by Shuyan Zhang (426593)

“…Nationally, the United States of America reported the largest increase in age-standardized DALY rates and EAPC for ASIR (EAPC of 4.88, 1.05, respectively), while South Africa had the most significant decrease in EAPC (EAPC of −3.62, −1.52, respectively). …”

Data Sheet 2_Phase 2 trial (NCI-COTC030) of adjuvant inhaled recombinant human IL-15 combined with amputation and adjuvant chemotherapy in dogs with appendicular osteosarcoma.pdf by Robert B. Rebhun (8479020)

“…Cytotoxicity assays of PBMCs showed significant decreases after both surgery and chemotherapy with an overall decrease from the start to end of therapy (-18.2 ± 16.1%, P<0.001). …”

Data Sheet 1_Phase 2 trial (NCI-COTC030) of adjuvant inhaled recombinant human IL-15 combined with amputation and adjuvant chemotherapy in dogs with appendicular osteosarcoma.pdf by Robert B. Rebhun (8479020)

“…Cytotoxicity assays of PBMCs showed significant decreases after both surgery and chemotherapy with an overall decrease from the start to end of therapy (-18.2 ± 16.1%, P<0.001). …”

Data Sheet 1_Abundance, occurrence, and degradation of airborne antibiotic resistance genes in coastal and marine atmospheres.docx by Shijie Jia (5749301)

“…<p>Antibiotic resistance genes (ARGs) may have significant impacts on human health and ecosystems. …”

Data Sheet 1_Inhibitior of Bcl6 by FX1 protects DSS induced colitis mice through anti-inflammatory effects.pdf by Ruixian Liu (5743817)

“…</p>Results<p>In the treat group, colitis symptoms in mice were significantly improved, and there was a decrease in proportion of macrophages and protection of intestinal mucosal integrity-indicating anti-inflammatory effects of FX1. …”

Table 1_Inhibitior of Bcl6 by FX1 protects DSS induced colitis mice through anti-inflammatory effects.docx by Ruixian Liu (5743817)

“…</p>Results<p>In the treat group, colitis symptoms in mice were significantly improved, and there was a decrease in proportion of macrophages and protection of intestinal mucosal integrity-indicating anti-inflammatory effects of FX1. …”

Image 3_Inhibitior of Bcl6 by FX1 protects DSS induced colitis mice through anti-inflammatory effects.pdf by Ruixian Liu (5743817)

“…</p>Results<p>In the treat group, colitis symptoms in mice were significantly improved, and there was a decrease in proportion of macrophages and protection of intestinal mucosal integrity-indicating anti-inflammatory effects of FX1. …”

Table 1_The activity of cell-free supernatant of Lactobacillus crispatus M247: a promising treatment against vaginal infections.docx by Giulia Santarelli (14246638)

“…In a series of in vitro infection models, we infected Henrietta Lacks’ cervical eukaryotic cancer cells (HeLa) with E. coli, S. agalactiae and C. albicans at specific multiplicities of infection (MOIs) before the administration of LcM247, CFS, gentamicin or fluconazole alone or in combination with LcM247/CFS. We observed a slight decrease in the microbial burden following LcM247 administration, while treatment with CFS significantly reduced microbial growth compared to control and antimicrobial compounds. …”

Image 3_The activity of cell-free supernatant of Lactobacillus crispatus M247: a promising treatment against vaginal infections.png by Giulia Santarelli (14246638)

“…In a series of in vitro infection models, we infected Henrietta Lacks’ cervical eukaryotic cancer cells (HeLa) with E. coli, S. agalactiae and C. albicans at specific multiplicities of infection (MOIs) before the administration of LcM247, CFS, gentamicin or fluconazole alone or in combination with LcM247/CFS. We observed a slight decrease in the microbial burden following LcM247 administration, while treatment with CFS significantly reduced microbial growth compared to control and antimicrobial compounds. …”

Table 4_The activity of cell-free supernatant of Lactobacillus crispatus M247: a promising treatment against vaginal infections.xlsx by Giulia Santarelli (14246638)

“…In a series of in vitro infection models, we infected Henrietta Lacks’ cervical eukaryotic cancer cells (HeLa) with E. coli, S. agalactiae and C. albicans at specific multiplicities of infection (MOIs) before the administration of LcM247, CFS, gentamicin or fluconazole alone or in combination with LcM247/CFS. We observed a slight decrease in the microbial burden following LcM247 administration, while treatment with CFS significantly reduced microbial growth compared to control and antimicrobial compounds. …”

Image 5_Inhibitior of Bcl6 by FX1 protects DSS induced colitis mice through anti-inflammatory effects.pdf by Ruixian Liu (5743817)

“…</p>Results<p>In the treat group, colitis symptoms in mice were significantly improved, and there was a decrease in proportion of macrophages and protection of intestinal mucosal integrity-indicating anti-inflammatory effects of FX1. …”

Data Sheet 1_Host identity, more than elevation, shapes bee microbiomes along a tropical elevation gradient.pdf by Andrea Pinos (22268176)

“…Within tribes, the turnover of microbial compositions was mainly explained by environmental changes with elevation in bumble and stingless bees. The observed variations in gut microbial diversity and composition at different elevations and different host taxa suggest that both factors significantly impact the gut microbiomes. …”

Table 3_The activity of cell-free supernatant of Lactobacillus crispatus M247: a promising treatment against vaginal infections.xlsx by Giulia Santarelli (14246638)

“…In a series of in vitro infection models, we infected Henrietta Lacks’ cervical eukaryotic cancer cells (HeLa) with E. coli, S. agalactiae and C. albicans at specific multiplicities of infection (MOIs) before the administration of LcM247, CFS, gentamicin or fluconazole alone or in combination with LcM247/CFS. We observed a slight decrease in the microbial burden following LcM247 administration, while treatment with CFS significantly reduced microbial growth compared to control and antimicrobial compounds. …”

Data Sheet 1_Unveiling the effects of land use and intra-seasonal variation on bee and plant diversity and their ecological interactions in vegetation surrounding coffee plantation... by Quebin Bosbely Casiá-Ajché (14234267)

“…<p>Land use, local management, and seasonal variation significantly impact the ecological dynamics of bee–plant communities and their ecological interactions. …”

Image 1_Inhibitior of Bcl6 by FX1 protects DSS induced colitis mice through anti-inflammatory effects.pdf by Ruixian Liu (5743817)

“…</p>Results<p>In the treat group, colitis symptoms in mice were significantly improved, and there was a decrease in proportion of macrophages and protection of intestinal mucosal integrity-indicating anti-inflammatory effects of FX1. …”

Image 2_The activity of cell-free supernatant of Lactobacillus crispatus M247: a promising treatment against vaginal infections.png by Giulia Santarelli (14246638)

“…In a series of in vitro infection models, we infected Henrietta Lacks’ cervical eukaryotic cancer cells (HeLa) with E. coli, S. agalactiae and C. albicans at specific multiplicities of infection (MOIs) before the administration of LcM247, CFS, gentamicin or fluconazole alone or in combination with LcM247/CFS. We observed a slight decrease in the microbial burden following LcM247 administration, while treatment with CFS significantly reduced microbial growth compared to control and antimicrobial compounds. …”

Table 2_Inhibitior of Bcl6 by FX1 protects DSS induced colitis mice through anti-inflammatory effects.docx by Ruixian Liu (5743817)

“…</p>Results<p>In the treat group, colitis symptoms in mice were significantly improved, and there was a decrease in proportion of macrophages and protection of intestinal mucosal integrity-indicating anti-inflammatory effects of FX1. …”