يعرض 4,421 - 4,440 نتائج من 4,762 نتيجة بحث عن '(( significant decrease decrease ) OR ( significantly observed decrease ))~', وقت الاستعلام: 0.39s تنقيح النتائج
  1. 4421

    Table 4_Fatty acid synthase inhibition improves hypertension-induced erectile dysfunction by suppressing oxidative stress and NLRP3 inflammasome-dependent pyroptosis through activa... حسب Jiaochen Luan (9704384)

    منشور في 2025
    "…Additionally, increased expression of the NLRP3 inflammasome, Caspase-1, GSDMD, and the pro-inflammatory cytokines IL-1β and IL-18 was observed. Multi-omics analysis revealed significant enrichment in lipid metabolic pathways, with Fasn identified as a hub gene. …"
  2. 4422

    Image 1_Association between controlling nutritional status score and mortality in older patients with dysphagia in Japan: a retrospective cohort study.tif حسب Yan Wang (15435)

    منشور في 2025
    "…Median survival durations decreased progressively: 716 days (mild), 362 days (moderate), and 106 days (severe). …"
  3. 4423

    Image 3_Fatty acid synthase inhibition improves hypertension-induced erectile dysfunction by suppressing oxidative stress and NLRP3 inflammasome-dependent pyroptosis through activa... حسب Jiaochen Luan (9704384)

    منشور في 2025
    "…Additionally, increased expression of the NLRP3 inflammasome, Caspase-1, GSDMD, and the pro-inflammatory cytokines IL-1β and IL-18 was observed. Multi-omics analysis revealed significant enrichment in lipid metabolic pathways, with Fasn identified as a hub gene. …"
  4. 4424

    Data Sheet 1_An analysis of the global burden of childhood and adolescent asthma attributable to high BMI: 1990–2021.pdf حسب Xinhui Zhang (1624039)

    منشور في 2025
    "…Statistical analysis showed a significant correlation between SDI and asthma burden (P < 0.001), with the overall disease burden increasing as SDI rose. …"
  5. 4425

    Figure 2 from Loss of Sorting Nexin 10 Accelerates KRAS-Induced Pancreatic Tumorigenesis حسب Kohinoor Khan (22206206)

    منشور في 2025
    "…<p>OE of SNX10 decreased cell proliferation in AsPC1 and HPAF-II PDAC cell lines. …"
  6. 4426

    Image 5_Fatty acid synthase inhibition improves hypertension-induced erectile dysfunction by suppressing oxidative stress and NLRP3 inflammasome-dependent pyroptosis through activa... حسب Jiaochen Luan (9704384)

    منشور في 2025
    "…Additionally, increased expression of the NLRP3 inflammasome, Caspase-1, GSDMD, and the pro-inflammatory cytokines IL-1β and IL-18 was observed. Multi-omics analysis revealed significant enrichment in lipid metabolic pathways, with Fasn identified as a hub gene. …"
  7. 4427

    Data Sheet 1_Fatty acid synthase inhibition improves hypertension-induced erectile dysfunction by suppressing oxidative stress and NLRP3 inflammasome-dependent pyroptosis through a... حسب Jiaochen Luan (9704384)

    منشور في 2025
    "…Additionally, increased expression of the NLRP3 inflammasome, Caspase-1, GSDMD, and the pro-inflammatory cytokines IL-1β and IL-18 was observed. Multi-omics analysis revealed significant enrichment in lipid metabolic pathways, with Fasn identified as a hub gene. …"
  8. 4428

    Data corresponding to the publication by Di Miceli, Rossitto, Martinat, Marchaland, Kharbouche, Graland, Younes, Séré, Aubert, Rabbaa Khabbaz, Madore, Delpech, Martín & Layé. حسب Mathieu Di Miceli (6318911)

    منشور في 2024
    "…However, at PND21, abnormal social interaction was witnessed in male and female animals born by CSD, with significantly decreased time spent interacting during the social interaction test. …"
  9. 4429

    Video 1_Safety and effectiveness of a new minimally invasive glaucoma surgery namely trabeculotome tunneling trabeculoplasty in primary open-angle glaucoma.mp4 حسب Suzhen Wang (163752)

    منشور في 2025
    "…Postoperative IOP significantly decreased at all follow-up points except at 1 week (p < 0.05). …"
  10. 4430

    Data Sheet 2_Assessing the evolution of infectious disease preparedness among a province with poor economy in China in the wake of COVID-19.docx حسب Huaying Liu (8312517)

    منشور في 2025
    "…The participation rate in emergency treatment of infectious diseases rose to 63.51% after COVID-19, from 58.33% of physicians lacking infectious disease training before the pandemic, which decreased to 35.60% post-pandemic. Currently, “community family medical observation” is the most sought-after training content among Guangxis grassroots physicians (31.25%).…"
  11. 4431

    Supplementary Material for: The role of reactive oxygen species in the pathogenesis of alopecia areata: a systematic review and meta-analysis. حسب Perlmutter J. (11590717)

    منشور في 2025
    "…Background: Alopecia areata (AA) is a T-cell-mediated autoimmune disease that significantly impacts patient quality of life. The breakdown of hair follicle immune privilege underlies AA pathogenesis. …"
  12. 4432

    Data Sheet 1_Assessing the evolution of infectious disease preparedness among a province with poor economy in China in the wake of COVID-19.docx حسب Huaying Liu (8312517)

    منشور في 2025
    "…The participation rate in emergency treatment of infectious diseases rose to 63.51% after COVID-19, from 58.33% of physicians lacking infectious disease training before the pandemic, which decreased to 35.60% post-pandemic. Currently, “community family medical observation” is the most sought-after training content among Guangxis grassroots physicians (31.25%).…"
  13. 4433

    Genetic interaction between <i>Zrf1</i> and RISC components regulates ISC proliferation during midgut damage. حسب Joshua Shing Shun Li (22505522)

    منشور في 2025
    "…Females carrying <i><i>Zrf1</i></i><sup><i>242</i></sup><i>/ +</i> combined with heterozygous mutant alleles for RISC components (<i><i>Fmr1</i></i><sup><i>d113M</i></sup><i><i>, vig</i></i><sup><i>d65-72</i></sup><i><i>, vig</i></i><sup><i>d63-73</i></sup><i><i>, vig2</i></i><sup><i>Gd59-75</i></sup>, and <i>AGO2</i><sup><i>454</i></sup>) are compared to individual heterozygotes. Significant reductions in ISC proliferation are observed in certain double heterozygotes, suggesting a synergistic interaction between <i><i>Zrf1</i></i> and these RISC components. …"
  14. 4434

    PbCBP-O is required for efficient midgut traversal. حسب Dominika Kwecka (22170493)

    منشور في 2025
    "…In all relevant panels, statistical significance is indicated as: ns = not significant, ** = p < 0.01, *** = p < 0.001 and **** = p < 0.0001.…"
  15. 4435

    Image 6_Interleukin-6/soluble IL-6 receptor-induced secretion of cathepsin B and L from human gingival fibroblasts is regulated by caveolin-1 and ERK1/2 pathways.tiff حسب Ayaka Goto (20858771)

    منشور في 2025
    "…</p>Results<p>Cathepsins B and L were secreted in their precursor forms from HGFs, with significantly elevated protein levels observed at 24, 48, and 72 h post-IL-6/sIL-6R stimulation. …"
  16. 4436

    Image 1_Interleukin-6/soluble IL-6 receptor-induced secretion of cathepsin B and L from human gingival fibroblasts is regulated by caveolin-1 and ERK1/2 pathways.tiff حسب Ayaka Goto (20858771)

    منشور في 2025
    "…</p>Results<p>Cathepsins B and L were secreted in their precursor forms from HGFs, with significantly elevated protein levels observed at 24, 48, and 72 h post-IL-6/sIL-6R stimulation. …"
  17. 4437

    Table 1_Combined inhibition of dopamine D1/D2 receptors induces cognitive and emotional dysfunction through oxidative stress and dopaminergic neuron damage.xls حسب Xue Li (285380)

    منشور في 2025
    "…</p>Results<p>Low-dose co-DR1/2I significantly increased MAO-B and ROS levels (p < 0.01) and decreased SOD activity (p < 0.01) in the substantia nigra, striatum, and hippocampus. …"
  18. 4438

    Image 3_Interleukin-6/soluble IL-6 receptor-induced secretion of cathepsin B and L from human gingival fibroblasts is regulated by caveolin-1 and ERK1/2 pathways.tiff حسب Ayaka Goto (20858771)

    منشور في 2025
    "…</p>Results<p>Cathepsins B and L were secreted in their precursor forms from HGFs, with significantly elevated protein levels observed at 24, 48, and 72 h post-IL-6/sIL-6R stimulation. …"
  19. 4439

    Data Sheet 4_Combined inhibition of dopamine D1/D2 receptors induces cognitive and emotional dysfunction through oxidative stress and dopaminergic neuron damage.zip حسب Xue Li (285380)

    منشور في 2025
    "…</p>Results<p>Low-dose co-DR1/2I significantly increased MAO-B and ROS levels (p < 0.01) and decreased SOD activity (p < 0.01) in the substantia nigra, striatum, and hippocampus. …"
  20. 4440

    Supplementary file 1_Burden of hypertensive heart disease attributed to metabolic factors from 1990 to 2021 at global, regional, and national levels: an analysis of the global burd... حسب Bo Peng (273834)

    منشور في 2025
    "…</p>Results<p>In 2021, deaths and DALYs due to HSBP and high BMI significantly increased compared to 1990. However, the ASMR for HSBP-related HHD [EAPC: −0.68; 95% confidence interval (CI): −0.77 to −0.58] and ASDR (EAPC: −0.90; 95% CI: −0.99 to −0.80) showed a decreasing trend, while the ASMR for BMI-related HHD (EAPC: 0.33; 95% CI: 0.27–0.39) and ASDR (EAPC: 0.15; 95% CI: 0.10–0.21) exhibited an increasing trend. …"