Image 1_SarZ inhibits the hemolytic activity through regulation of phenol soluble modulins in Staphylococcus epidermidis.jpeg by Xiao Chen (260187)

“…The sarZ psmβ double mutant was further generated and displayed a significantly decreased hemolytic activity compared with the sarZ mutant. …”

Image 4_SarZ inhibits the hemolytic activity through regulation of phenol soluble modulins in Staphylococcus epidermidis.jpeg by Xiao Chen (260187)

“…The sarZ psmβ double mutant was further generated and displayed a significantly decreased hemolytic activity compared with the sarZ mutant. …”

Supplementary file 1_Forced intensity-controlled endurance training on a small-animal treadmill machine inducing murine cardiac hypertrophy: insights and comparison to voluntary ru... by Maximillian Fischer (14758063)

“…In addition, transcriptomic analysis of 8-week training hearts was evaluated using RNA sequencing. Endurance training promotes significant body weight loss in training mice as early as 2 weeks. …”

Data Sheet 1_Methylglyoxal induces oxidative stress and ferroptosis of renal tubular epithelial cells in acute and chronic kidney injury mice.docx by Yongzheng Zhang (1479694)

“…In HK-2 cells, MG treatment induced cytotoxicity, increased intracellular reactive oxygen species (ROS) levels, triggered ferroptosis by increasing LPO, and decreased glutathione (GSH) levels. These findings suggest a potential association between MG accumulation and kidney injury and indicate that MG promotes ferroptosis specifically in renal TECs. …”

The regulation of AsfR on tmRNA expression mediates bacterial motility and virulence by Huimin Chang (21142907)

“…Consistently, the transcription level of tmRNA was significantly decreased in Δ<i>asfR</i> compared with WT of <i>A. veronii </i>by quantitative real-time PCR (RT-qPCR) analyses. …”

Table 1_A study of the adjunctive therapeutic effects of a 3-week bamboo forest therapy on chronic diseases in the elderly.docx by Jing He (58446)

“…Diabetic participants showed significant decreases in fasting and pre-bedtime blood glucose levels (p < 0.001), along with reduced blood glucose fluctuations post-meal. …”

CARE-checklist JOSPT[1].docx by Sanjivani Bangde (19749151)

“…DASH score was decreased.</p><p dir="ltr"><b>Conclusion</b>: This case highlights the importance of early targeted rehabilitation to promote recovery and restore joint function after ligament repair. …”

Table 1_Bacteroides ovatus-derived N-methylserotonin inhibit colorectal cancer via the HTR1D-mediated cAMP-PKA-NF-κB signaling axis.docx by Jikai He (11888466)

“…</p>Results<p>(1) CRC patients showed significantly increased metabolic pathways including glycolysis, methane metabolism, beneficial amino acid degradation, and linoleic acid degradation, along with significantly decreased B.o abundance and NMS levels, which were positively correlated; (2) NMS significantly inhibited CRC cell proliferation, migration, and invasion, while promoting apoptosis; (3) Combined treatment with B.o and orange fiber or NMS alone reduced tumorigenesis and improved intestinal barrier function; (4) Mechanistic studies revealed that these effects could be mediated through downregulation of 5-hydroxytryptamine receptor 1D (HTR1D) expression and inhibition of the cAMP/PKA/IκBα/NF-κB pathway; (5) The treatments optimized gut microbiota structure and metabolite composition.…”

Table 2_Bacteroides ovatus-derived N-methylserotonin inhibit colorectal cancer via the HTR1D-mediated cAMP-PKA-NF-κB signaling axis.xlsx by Jikai He (11888466)

“…</p>Results<p>(1) CRC patients showed significantly increased metabolic pathways including glycolysis, methane metabolism, beneficial amino acid degradation, and linoleic acid degradation, along with significantly decreased B.o abundance and NMS levels, which were positively correlated; (2) NMS significantly inhibited CRC cell proliferation, migration, and invasion, while promoting apoptosis; (3) Combined treatment with B.o and orange fiber or NMS alone reduced tumorigenesis and improved intestinal barrier function; (4) Mechanistic studies revealed that these effects could be mediated through downregulation of 5-hydroxytryptamine receptor 1D (HTR1D) expression and inhibition of the cAMP/PKA/IκBα/NF-κB pathway; (5) The treatments optimized gut microbiota structure and metabolite composition.…”

Table 6_Comparative proteomic analysis of the telogen-to-anagen transition in cashmere goat secondary hair follicles.xls by Xiaoyu Han (550622)

“…Their expression levels were significantly enhanced during anagen. ADAM17 is suggested to promote the growth of SHFs by regulating ORS cells proliferation and mediating signal transduction in DPCs, while SFRP1, as a modulator of the Wnt signaling pathway, likely supports SHFs growth and regeneration by modulating the activity of Secondary hair follicle stem cells (SHFSCs) and promoting the differentiation of HMCs. …”

Table 2_Comparative proteomic analysis of the telogen-to-anagen transition in cashmere goat secondary hair follicles.pdf by Xiaoyu Han (550622)

“…Their expression levels were significantly enhanced during anagen. ADAM17 is suggested to promote the growth of SHFs by regulating ORS cells proliferation and mediating signal transduction in DPCs, while SFRP1, as a modulator of the Wnt signaling pathway, likely supports SHFs growth and regeneration by modulating the activity of Secondary hair follicle stem cells (SHFSCs) and promoting the differentiation of HMCs. …”

Table 5_Comparative proteomic analysis of the telogen-to-anagen transition in cashmere goat secondary hair follicles.csv by Xiaoyu Han (550622)

“…Their expression levels were significantly enhanced during anagen. ADAM17 is suggested to promote the growth of SHFs by regulating ORS cells proliferation and mediating signal transduction in DPCs, while SFRP1, as a modulator of the Wnt signaling pathway, likely supports SHFs growth and regeneration by modulating the activity of Secondary hair follicle stem cells (SHFSCs) and promoting the differentiation of HMCs. …”

Table 3_Comparative proteomic analysis of the telogen-to-anagen transition in cashmere goat secondary hair follicles.pdf by Xiaoyu Han (550622)

“…Their expression levels were significantly enhanced during anagen. ADAM17 is suggested to promote the growth of SHFs by regulating ORS cells proliferation and mediating signal transduction in DPCs, while SFRP1, as a modulator of the Wnt signaling pathway, likely supports SHFs growth and regeneration by modulating the activity of Secondary hair follicle stem cells (SHFSCs) and promoting the differentiation of HMCs. …”

Table 4_Comparative proteomic analysis of the telogen-to-anagen transition in cashmere goat secondary hair follicles.csv by Xiaoyu Han (550622)

“…Their expression levels were significantly enhanced during anagen. ADAM17 is suggested to promote the growth of SHFs by regulating ORS cells proliferation and mediating signal transduction in DPCs, while SFRP1, as a modulator of the Wnt signaling pathway, likely supports SHFs growth and regeneration by modulating the activity of Secondary hair follicle stem cells (SHFSCs) and promoting the differentiation of HMCs. …”

Table 1_Comparative proteomic analysis of the telogen-to-anagen transition in cashmere goat secondary hair follicles.pdf by Xiaoyu Han (550622)

“…Their expression levels were significantly enhanced during anagen. ADAM17 is suggested to promote the growth of SHFs by regulating ORS cells proliferation and mediating signal transduction in DPCs, while SFRP1, as a modulator of the Wnt signaling pathway, likely supports SHFs growth and regeneration by modulating the activity of Secondary hair follicle stem cells (SHFSCs) and promoting the differentiation of HMCs. …”

Figure 5 from Integrated Molecular Characterization of Patient-Derived Models Reveals Therapeutic Strategies for Treating CIC-DUX4 Sarcoma by Marianna Carrabotta (8193039)

“…Trabectedin can impair HMGA2 activity by preventing its binding to promoters, thus inhibiting the transcription of its targets <i>IGF2BP2</i> and <i>IGF2BP3</i> and decreasing IGF2/IGF1R signaling. …”

Effect of overexpressing <i>CEBPB</i> and <i>GFI-1</i> on <i>SOST</i> expression. by Avneesh Chopra (20927514)

“…</b> <i>GFI-1</i> CRISPRa did not increase <i>SOST</i> expression in Hela cells. <i>GFI-1</i> was significantly upregulated 48 h after transfection of CRISPRa plasmids with sgRNAs that targeted the GFI promoter (43-fold, P <  0.0001; <b>left panel</b>). …”

Table 1_Mechanism of action of decitabine in treating acute lymphoblastic leukemia.docx by Xiaohui Gao (308514)

“…Animal experimental results indicated that both DAC and doxorubicin substantially decreased tumor length, width, volume, and mass; however, DAC demonstrated significantly superior efficacy in inhibiting tumor growth compared to doxorubicin.…”

Table 1_Dynamic evolution and influencing factors of green total factor productivity in the Yangtze River Economic Belt: a study based on the three-stage SBM-ML index model.xlsx by Fei Chen (13690)

“…Although urbanization was initially insignificant, it significantly boosted real GTFP post-COVID-19. Finally, policy recommendations to promote green development in river basins are proposed.…”

Data Sheet 1_The response regulator CrsR positively regulates ansamitocin P-3 biosynthesis in Actinosynnema pretiosum.docx by Peipei Zhang (1360440)

“…Deletion of the response regulator gene crsR drastically decreased AP-3 production. RNA-seq revealed CrsR’s global regulatory role, significantly altering transcription of primary metabolic genes, especially those in purine metabolism. …”